Narendra Chirmule

Overview

Best Publications

• Fatal systemic inflammatory response syndrome in a ornithine transcarbamylase deficient patient following adenoviral gene transfer

  Steven E Raper;Narendra Chirmule;Frank S Lee;Nelson A Wivel

  1817
  Citations

• Immune responses to adenovirus and adeno-associated virus in humans.

  N Chirmule;K J Propert;S A Magosin;Y Qian

  893
  Citations

• Gene therapy vectors based on adeno-associated virus type 1

  Weidong Xiao;Narendra Chirmule;Scott C. Berta;Beth McCullough

  712
  Citations

• Acute cytokine response to systemic adenoviral vectors in mice is mediated by dendritic cells and macrophages.

  Yi Zhang;Narendra Chirmule;Guang Ping Gao;Ruth Qian

  472
  Citations

• A pilot study of in vivo liver-directed gene transfer with an adenoviral vector in partial ornithine transcarbamylase deficiency.

  Steven E. Raper;Marc Yudkoff;Narendra Chirmule;Guang-Ping Gao

  464
  Citations

• Immunity to adenovirus and adeno-associated viral vectors: implications for gene therapy.

  K Jooss;N Chirmule

  371
  Citations

• Simultaneous Quantitation of Antibodies to Neutralizing Epitopes on Virus-Like Particles for Human Papillomavirus Types 6, 11, 16, and 18 by a Multiplexed Luminex Assay

  David Opalka;Charles E. Lachman;Stefani A. MacMullen;Kathrin U. Jansen

  340
  Citations

• Immunogenicity to Therapeutic Proteins: Impact on PK/PD and Efficacy

  Narendra Chirmule;Vibha Jawa;Bernd Meibohm

  325
  Citations

• Stable transgene expression in rod photoreceptors after recombinant adeno-associated virus-mediated gene transfer to monkey retina

  Jean Bennett;Albert M. Maguire;Artur V. Cideciyan;Michael Schnell

  302
  Citations

• “Stealth” Adenoviruses Blunt Cell-Mediated and Humoral Immune Responses against the Virus and Allow for Significant Gene Expression upon Readministration in the Lung

  Maria A. Croyle;Narendra Chirmule;Yi Zhang;James M. Wilson

  300
  Citations

• Optimization and validation of a multiplexed luminex assay to quantify antibodies to neutralizing epitopes on human papillomaviruses 6, 11, 16, and 18

  Dennis Dias;Jeff Van Doren;Sonela Schlottmann;Sheri Kelly

  284
  Citations

• Memory T cells and vaccines.

  Mark T. Esser;Rocio D. Marchese;Lisa S. Kierstead;Lynda G. Tussey

  281
  Citations

• Hybrid Vectors Based on Adeno-Associated Virus Serotypes 2 and 5 for Muscle-Directed Gene Transfer

  Markus Hildinger;Alberto Auricchio;Guangping Gao;Lili Wang

  268
  Citations

• Accelerated apoptosis in peripheral blood mononuclear cells (PBMCs) from human immunodeficiency virus type-1 infected patients and in CD4 cross-linked PBMCs from normal individuals

  Naoki Oyaizu;Thomas W. McCloskey;Maria Coronesi;Narendra Chirmule

  260
  Citations

• Immune hyperactivation of HIV-1-infected T cells mediated by Tat and the CD28 pathway.

  Melanie Ott;Stephane Emiliani;Carine Van Lint;Georges Herbein

  255
  Citations

• Humoral Immunity to Adeno-Associated Virus Type 2 Vectors following Administration to Murine and Nonhuman Primate Muscle

  Narendra Chirmule;Weidong Xiao;Alemseged Truneh;Michael A. Schnell

  239
  Citations

• Immunogenicity of Biotherapeutics: Causes and Association with Posttranslational Modifications.

  Anshu Kuriakose;Narendra Chirmule;Pradip Nair

  227
  Citations

• Purification of recombinant adeno-associated virus vectors by column chromatography and its performance in vivo.

  Guangping Gao;Guang Qu;Michael S. Burnham;James Huang

  220
  Citations

• A phase I study of adenovirus-mediated transfer of the human cystic fibrosis transmembrane conductance regulator gene to a lung segment of individuals with cystic fibrosis.

  Jonathan B. Zuckerman;Cynthia B. Robinson;Karen S. McCoy;Richard Shell

  211
  Citations

• Muscle-Specific Promoters May Be Necessary for Adeno-Associated Virus-Mediated Gene Transfer in the Treatment of Muscular Dystrophies

  Laurence Cordier;Guang-Ping Gao;Andrew A. Hack;Elizabeth M. McNally

  203
  Citations