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Mitsuyoshi Nakao

Mitsuyoshi Nakao

D-Index & Metrics

Molecular Biology

D-Index
70
Citations
15726
World Ranking
1435
National Ranking
122

Overview

Mitsuyoshi Nakao is a researcher affiliated with Kumamoto University in Japan. Their body of work spans primarily the fields of Biochemistry, Genetics, and Molecular Biology, with additional contributions in Medicine. Within these areas, Nakao has focused on several subfields including Molecular Biology, Physiology, Oncology, Genetics, and Cell Biology.

Their research topics encompass a range of issues related to epigenetics, RNA, and cancer, covering:

  • Epigenetics and DNA Methylation
  • RNA modifications and cancer
  • Genomics and Chromatin Dynamics
  • Cancer-related gene regulation
  • Genomics, phytochemicals, and oxidative stress
  • RNA Research and Splicing
  • RNA regulation and disease

Several recent papers illustrate Nakao's contributions to these areas:

  • "Splicing- and demethylase-independent functions of LSD1 in zebrafish primitive hematopoiesis" (2020), published in Scientific Reports
  • "Phosphorylation of phase-separated p62 bodies by ULK1 activates a redox-independent stress response" (2023), published in The EMBO Journal
  • "A web-based integrative transcriptome analysis, RNAseqChef, uncovers the cell/tissue type-dependent action of sulforaphane" (2023), published in Journal of Biological Chemistry
  • "Murine neonatal ketogenesis preserves mitochondrial energetics by preventing protein hyperacetylation" (2021), published in Nature Metabolism
  • "Successful generation of epigenetic disease model mice by targeted demethylation of the epigenome" (2020), published in Genome Biology

Nakao has published frequently in journals such as bioRxiv (Cold Spring Harbor Laboratory), Scientific Reports, The EMBO Journal, Cell Reports, and Cancer Science.

Frequent collaborators in Nakao's research include:

  • Shinjiro Hino
  • Yuko Hino
  • Tomoaki Koga
  • Kan Etoh
  • Noriko Saitoh

Best Publications

  • Cohesin mediates transcriptional insulation by CCCTC-binding factor

    Kerstin S. Wendt;Keisuke Yoshida;Takehiko Itoh;Masashige Bando

  • DNA methylation is a critical cell-intrinsic determinant of astrocyte differentiation in the fetal brain.

    Takumi Takizawa;Kinichi Nakashima;Masakazu Namihira;Wataru Ochiai

  • Deletions of a differentially methylated CpG island at the SNRPN gene define a putative imprinting control region

    James S. Sutcliffe;Mitsuyoshi Nakao;Susan Christian;Karen H. Örstavik

  • CTCF-Dependent Chromatin Insulator Is Linked to Epigenetic Remodeling

    Ko Ishihara;Mitsuo Oshimura;Mitsuyoshi Nakao

  • Methyl-CpG binding domain 1 (MBD1) interacts with the Suv39h1-HP1 heterochromatic complex for DNA methylation-based transcriptional repression

    Naoyuki Fujita;Sugiko Watanabe;Takaya Ichimura;Shu Tsuruzoe

  • CD44 cleavage induced by a membrane-associated metalloprotease plays a critical role in tumor cell migration.

    Isamu Okamoto;Yoshiaki Kawano;Hiromasa Tsuiki;Ji Ichiro Sasaki

  • Epigenetics: interaction of DNA methylation and chromatin

    Mitsuyoshi Nakao

  • FAD-dependent lysine-specific demethylase-1 regulates cellular energy expenditure

    Shinjiro Hino;Akihisa Sakamoto;Katsuya Nagaoka;Kotaro Anan

  • Nedd4 Regulates Egress of Ebola Virus-Like Particles from Host Cells

    Jiro Yasuda;Mitsuyoshi Nakao;Yoshihiro Kawaoka;Hisatoshi Shida

  • HMGA2 maintains oncogenic RAS-induced epithelial-mesenchymal transition in human pancreatic cancer cells.

    Sugiko Watanabe;Yasuaki Ueda;Shin Ichi Akaboshi;Yuko Hino

  • METHYLATION-MEDIATED TRANSCRIPTIONAL SILENCING IN EUCHROMATIN BY METHYL-CPG BINDING PROTEIN MBD1 ISOFORMS

    Naoyuki Fujita;Naoyuki Fujita;Shin Ichiro Takebayashi;Katsuzumi Okumura;Shinichi Kudo

  • Structures of human genes coding for cytokine LD78 and their expression.

    Mitsuyoshi Nakao;Hisayuki Nomiyama;Kazunori Shimada

  • Architectural roles of multiple chromatin insulators at the human apolipoprotein gene cluster

    Tsuyoshi Mishiro;Tsuyoshi Mishiro;Ko Ishihara;Shinjiro Hino;Shuichi Tsutsumi

  • H3K4/H3K9me3 Bivalent Chromatin Domains Targeted by Lineage-Specific DNA Methylation Pauses Adipocyte Differentiation

    Yoshihiro Matsumura;Ryo Nakaki;Takeshi Inagaki;Ayano Yoshida

  • Human T-cell leukemia virus type 1 bZIP factor selectively suppresses the classical pathway of NF-κB

    Tiejun Zhao;Jun Ichirou Yasunaga;Yorifumi Satou;Mitsuyoshi Nakao

  • Activation of Cdh1-dependent APC is required for G1 cell cycle arrest and DNA damage-induced G2 checkpoint in vertebrate cells

    Tamotsu Sudo;Yosuke Ota;Shuji Kotani;Mitsuyoshi Nakao

  • Transcriptional blockade induces p53-dependent apoptosis associated with translocation of p53 to mitochondria.

    Yoshimi Arima;Masayuki Nitta;Shinji Kuninaka;Dongwei Zhang

  • Mechanism of Transcriptional Regulation by Methyl-CpG Binding Protein MBD1

    Naoyuki Fujita;Nobuya Shimotake;Izuru Ohki;Tsutomu Chiba

  • A novel maternally expressed gene, ATP10C, encodes a putative aminophospholipid translocase associated with Angelman syndrome.

    Makiko Meguro;Akiko Kashiwagi;Kohzoh Mitsuya;Mitsuyoshi Nakao

  • Calcium influx triggers the sequential proteolysis of extracellular and cytoplasmic domains of E-cadherin, leading to loss of β-catenin from cell-cell contacts

    Kiyoharu Ito;Isamu Okamoto;Norie Araki;Yoshiaki Kawano

Frequent Co-Authors

Hideyuki Saya
Hideyuki Saya Fujita Health University
Hideo Baba
Hideo Baba Kumamoto University
James S. Sutcliffe
James S. Sutcliffe Vanderbilt University
Tsutomu Chiba
Tsutomu Chiba Kyoto University
Yasuyuki Ohkawa
Yasuyuki Ohkawa Kyushu University
Masahiro Shirakawa
Masahiro Shirakawa Kyoto University
Hiroyuki Aburatani
Hiroyuki Aburatani University of Tokyo
Masao Matsuoka
Masao Matsuoka Kumamoto University
Arthur L. Beaudet
Arthur L. Beaudet Baylor College of Medicine
David H. Ledbetter
David H. Ledbetter University of Florida

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