Endocrinology, Internal medicine, Cell biology, Biochemistry and Endocytosis are his primary areas of study. As part of his studies on Endocrinology, Michael Gekle often connects relevant subjects like Receptor. His Internal medicine research includes elements of Extracellular, Intracellular pH, Organic anion transporter 1 and Downregulation and upregulation.
Michael Gekle is interested in Kinase, which is a field of Cell biology. His study in Biochemistry is interdisciplinary in nature, drawing from both Cell culture, Kidney metabolism, In vivo and Pharmacology. His Endocytosis research includes themes of Reabsorption, Protein kinase C and Endosome.
The scientist’s investigation covers issues in Internal medicine, Endocrinology, Cell biology, Biochemistry and Kidney. He regularly ties together related areas like Signal transduction in his Internal medicine studies. As a part of the same scientific study, Michael Gekle usually deals with the Endocrinology, concentrating on Receptor and frequently concerns with Transactivation.
His Cell biology research focuses on Endocytosis and how it relates to Albumin and Endosome. His Biochemistry study combines topics in areas such as Molecular biology and Cell culture. The various areas that Michael Gekle examines in his Kidney study include Organic anion transporter 1, Ochratoxin A and Ion transporter.
Michael Gekle mostly deals with Endocrinology, Internal medicine, Cell biology, Vascular smooth muscle and Mineralocorticoid receptor. His study in Lipopolysaccharide and Nifedipine are all subfields of Internal medicine. His biological study spans a wide range of topics, including Cell culture, Transcriptome, microRNA, Proinflammatory cytokine and Programmed cell death.
His work deals with themes such as Extracellular, Extracellular matrix and Kidney, which intersect with Cell culture. His Mineralocorticoid receptor research is multidisciplinary, incorporating perspectives in Cirrhosis and Hypoxia. Michael Gekle combines subjects such as Aldosterone, Renal damage, Tissue homeostasis and Heart rate with his study of Epidermal growth factor receptor.
His scientific interests lie mostly in Cell culture, Molecular biology, Cell biology, Internal medicine and Endocrinology. His study in Cell culture is interdisciplinary in nature, drawing from both Cancer research, Tumor microenvironment, RNA, Cell adhesion and Motility. His work deals with themes such as HEK 293 cells and Proteome, which intersect with Molecular biology.
His Cell biology study combines topics in areas such as Transcriptome, Downregulation and upregulation, Post-transcriptional regulation, Caspase and microRNA. Internal medicine is often connected to Tissue homeostasis in his work. His Renal function research integrates issues from Acute kidney injury, Nitric oxide, Ischemia and Renal ischemia.
This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.
Renal tubule albumin transport.
Annual Review of Physiology (2005)
Characterization of two MDCK-cell subtypes as a model system to study principal cell and intercalated cell properties.
Michael Gekle;Stefan Wünsch;Hans Oberleithner;Stefan Silbernagl.
Pflügers Archiv: European Journal of Physiology (1994)
Cubilin- and megalin-mediated uptake of albumin in cultured proximal tubule cells of opossum kidney
Xiao Yue Zhai;Rikke Nielsen;Rikke Nielsen;Rikke Nielsen;Henrik Birn;Henrik Birn;Henrik Birn;Karina Drumm;Karina Drumm;Karina Drumm.
Kidney International (2000)
Human mineralocorticoid receptor expression renders cells responsive for nongenotropic aldosterone actions.
Claudia Grossmann;Andreas Benesic;Alexander W. Krug;Ruth Freudinger.
Molecular Endocrinology (2005)
Angiotensin Converting Enzyme Inhibition and Angiotensin II AT1-Receptor Blockade Reduce the Levels of Asymmetrical NG, NG-Dimethylarginine in Human Essential Hypertension*
Christian Delles;Markus P Schneider;Stefan John;Michael Gekle.
American Journal of Hypertension (2002)
Rapid activation of Na+/H+ exchange by aldosterone in renal epithelial cells requires Ca2+ and stimulation of a plasma membrane proton conductance.
Michael Gekle;Nikola Golenhofen;Hans Oberleithner;Stefan Silbernagl.
Proceedings of the National Academy of Sciences of the United States of America (1996)
Nephrotoxicity of platinum complexes is related to basolateral organic cation transport
Thomas Ludwig;Christoph Riethmüller;Christoph Riethmüller;Michael Gekle;Michael Gekle;Gerald Schwerdt;Gerald Schwerdt.
Kidney International (2004)
Impact of extracellular acidity on the activity of P-glycoprotein and the cytotoxicity of chemotherapeutic drugs.
Oliver Thews;Birgit Gassner;Debra K Kelleher;Gerald Schwerdt.
Ochratoxin A induces JNK activation and apoptosis in MDCK-C7 cells at nanomolar concentrations.
Michael Gekle;Gerald Schwerdt;Ruth Freudinger;Sigrid Mildenberger.
Journal of Pharmacology and Experimental Therapeutics (2000)
New aspects of rapid aldosterone signaling
C. Grossmann;M. Gekle.
Molecular and Cellular Endocrinology (2009)
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