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D-Index & Metrics

Biology and Biochemistry

D-Index
58
Citations
14926
World Ranking
13016
National Ranking
1016

Overview

Vera Knäuper is affiliated with Cardiff University in the United Kingdom. Their research focuses primarily on Medicine, with significant contributions across various subfields including Cell Biology, Hematology, Rehabilitation, Radiology, Nuclear Medicine and Imaging, and Oncology.

Their work addresses multiple main topics, notably:

  • Wound Healing and Treatments
  • Axon Guidance and Neuronal Signaling
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Alzheimer's disease research and treatments
  • Caveolin-1 and cellular processes
  • Single-cell and spatial transcriptomics
  • Cancer-related molecular mechanisms research

Vera Knäuper has contributed to several recent publications, including:

  • "Alzheimer's disease-associated P460L variant of EphA1 dysregulates receptor activity and blood-brain barrier function" (2024), published in Alzheimer s & Dementia
  • "Multi-Omics Analysis of Glioblastoma and Glioblastoma Cell Line: Molecular Insights Into the Functional Role of GPR56 and TG2 in Mesenchymal Transition" (2022), published in Frontiers in Oncology
  • "Cleavage by MMP-13 renders VWF unable to bind to collagen but increases its platelet reactivity" (2020), published in Journal of Thrombosis and Haemostasis
  • "Epoxytiglianes induce keratinocyte wound healing responses via classical protein kinase C activation to promote skin re-epithelialization" (2024), published in Biochemical Pharmacology
  • "Neutrophil collagenase (MMP-8) cleaves at the aggrecanase site E 373 -A 374 in the interglobular domain of cartilage aggrecan" (2020), published by UNC Libraries

The venues where Vera Knäuper frequently publishes include:

  • Alzheimer s & Dementia
  • Frontiers in Oncology
  • Journal of Thrombosis and Haemostasis
  • Biochemical Pharmacology
  • International Journal of Molecular Sciences

Vera Knäuper collaborates regularly with several researchers, including:

  • Owen Moon
  • Ann Ager
  • Lea Bauer
  • Daniel Aeschlimann
  • Paul Reddell

Best Publications

  • Biochemical Characterization of Human Collagenase-3

    Vera Knäuper;Carlos López-Otin;Bryan Smith;Graham Knight

  • Cellular Mechanisms for Human Procollagenase-3 (MMP-13) Activation EVIDENCE THAT MT1-MMP (MMP-14) AND GELATINASE A (MMP-2) ARE ABLE TO GENERATE ACTIVE ENZYME

    Vera Knäuper;Horst Will;Carlos López-Otin;Bryan Smith

  • TNF-α converting enzyme (TACE) is inhibited by TIMP-3

    Augustin Amour;Patrick M Slocombe;Ailsa Webster;Michael Butler

  • Mechanisms for pro matrix metalloproteinase activation.

    Gillian Murphy;Heather Stanton;Susan Cowell;Georgina Butler

  • The in vitro activity of ADAM-10 is inhibited by TIMP-1 and TIMP-3.

    Augustin Amour;C.Graham Knight;Ailsa Webster;Patrick M. Slocombe

  • Degradation of cartilage aggrecan by collagenase-3 (MMP-13)

    Amanda J. Fosang;Vera Knäuper;Gillian Murphy

  • The role of the C-terminal domain of human collagenase-3 (MMP-13) in the activation of procollagenase-3, substrate specificity, and tissue inhibitor of metalloproteinase interaction.

    Vera Knäuper;Susan Cowell;Bryan Smith;Carlos López-Otin

  • Matrix metalloproteinases in arthritic disease.

    Gillian Murphy;Vera Knäuper;Susan Atkinson;George Butler

  • Relating matrix metalloproteinase structure to function: why the "hemopexin" domain?

    Gillian Murphy;Vera Knäuper

  • Identification and Characterization of Human MT5-MMP, a New Membrane-bound Activator of Progelatinase A Overexpressed in Brain Tumors

    Elena Llano;Alberto M. Pendás;José P. Freije;Atsuhisa Nakano

  • Cloning and Characterization of Human MMP-23, a New Matrix Metalloproteinase Predominantly Expressed in Reproductive Tissues and Lacking Conserved Domains in Other Family Members

    Gloria Velasco;Alberto M. Pendás;Antonio Fueyo;Vera Knäuper

  • Endothelial tubulogenesis within fibrin gels specifically requires the activity of membrane-type-matrix metalloproteinases (MT-MMPs)

    Marc A. Lafleur;Madeleine M. Handsley;Vera Louise Frieda Knauper;Gillian Murphy

  • Identification and Structural and Functional Characterization of Human Enamelysin (MMP-20)†,‡

    Elena Llano;Alberto M. Pendás;Vera Knäuper;Timo Sorsa

  • ADAMTS1 cleaves aggrecan at multiple sites and is differentially inhibited by metalloproteinase inhibitors.

    Juan Carlos Rodriguez-Manzaneque;Jennifer Westling;Shelley N. M. Thai;Alfonso Luque

  • Identification and Characterization of a Novel Human Matrix Metalloproteinase with Unique Structural Characteristics, Chromosomal Location, and Tissue Distribution

    Alberto M. Pendás;Vera Knäuper;Xose S. Puente;Elena Llano

  • Membrane Type 4 Matrix Metalloproteinase (MMP17) Has Tumor Necrosis Factor-α Convertase Activity but Does Not Activate Pro-MMP2 *

    William R. English;Xose S. Puente;José M.P. Freije;Vera Knäuper

  • Identification and Enzymatic Characterization of Two Diverging Murine Counterparts of Human Interstitial Collagenase (MMP-1) Expressed at Sites of Embryo Implantation

    Milagros Balbı́n;Antonio Fueyo;Vera Knäuper;José M. López

  • Specific collagenolysis by gelatinase A, MMP-2, is determined by the hemopexin domain and not the fibronectin-like domain

    Margaret L Patterson;Susan J Atkinson;Vera Knäuper;Gillian Murphy

  • Activation of Progelatinase B (proMMP‐9) by Active Collagenase‐3 (MMP‐13)

    Vera Knäuper;Bryan Smith;Carlos López-Otin;Gillian Murphy

  • Induction of matrix metalloproteinase activation cascades based on membrane-type 1 matrix metalloproteinase: associated activation of gelatinase A, gelatinase B and collagenase 3

    Susan Cowell;Vera Knäuper;Margaret L. Stewart;Marie-Pia D'ortho

Frequent Co-Authors

Gillian Murphy
Gillian Murphy University of Cambridge
Carlos López-Otín
Carlos López-Otín University of Oviedo
Harald Tschesche
Harald Tschesche Bielefeld University
Alberto M. Pendás
Alberto M. Pendás University of Salamanca
Dylan R. Edwards
Dylan R. Edwards University of East Anglia
Andrew J. P. Docherty
Andrew J. P. Docherty UCB Pharma (Belgium)
Klaus Maskos
Klaus Maskos Proteros biostructures GmbH
Richard W. Farndale
Richard W. Farndale University of Cambridge
Rosalind M. Hembry
Rosalind M. Hembry University of East Anglia
José M. P. Freije
José M. P. Freije University of Oviedo

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