Marco M. Gottardis

Overview

Best Publications

• Phosphorylated Insulin-Like Growth Factor-I/Insulin Receptor Is Present in All Breast Cancer Subtypes and Is Related to Poor Survival

  Jennifer H. Law;Golareh Habibi;Kaiji Hu;Hamid Masoudi

  475
  Citations

• Effect of cadmium on estrogen receptor levels and estrogen-induced responses in human breast cancer cells.

  P. Garcia-Morales;M. Saceda;N. Kenney;N. Kim

  386
  Citations

• BMS-754807, a small molecule inhibitor of insulin-like growth factor-1R/IR

  Joan M. Carboni;Mark Wittman;Zheng Yang;Francis Lee

  375
  Citations

• Insulin-mediated acceleration of breast cancer development and progression in a nonobese model of type 2 diabetes.

  Ruslan Novosyadlyy;Danielle E. Lann;Archana Vijayakumar;Anne Rowzee;Anne Rowzee

  325
  Citations

• Decreased Egr‐1 expression in human, mouse and rat mammary cells and tissues correlates with tumor formation

  Ruo-Pan Huang;Yan Fan;Ian De Belle;Christina Niemeyer

  324
  Citations

• Constitutively Active Type I Insulin-Like Growth Factor Receptor Causes Transformation and Xenograft Growth of Immortalized Mammary Epithelial Cells and Is Accompanied by an Epithelial-to-Mesenchymal Transition Mediated by NF-κB and Snail

  Hyun Jung Kim;Beate C. Litzenburger;Xiaojiang Cui;David A. Delgado

  318
  Citations

• Chemoprevention of Mammary Carcinoma by LGD1069 (Targretin): An RXR-selective Ligand

  Marco M. Gottardis;Eric D. Bischoff;Michael A. Shirley;Murriel A. Wagoner

  296
  Citations

• In vitro and in vivo antitumor effects of the dual insulin-like growth factor-I/insulin receptor inhibitor, BMS-554417.

  Paul Haluska;Joan M. Carboni;David A. Loegering;Francis Y. Lee

  277
  Citations

• Castration-resistant prostate cancer: locking up the molecular escape routes.

  Ricardo M. Attar;Chris H. Takimoto;Marco M. Gottardis

  270
  Citations

• Tumor development by transgenic expression of a constitutively active insulin-like growth factor I receptor

  Joan M. Carboni;Adrian V. Lee;Darryl L. Hadsell;Bruce R. Rowley

  250
  Citations

• Estradiol-stimulated growth of MCF-7 tumors implanted in athymic mice: a model to study the tumoristatic action of tamoxifen.

  Marco M. Gottardis;Simon P. Robinson;V.Craig Jordan

  239
  Citations

• The mechanisms of differential sensitivity to an insulin-like growth factor-1 receptor inhibitor (BMS-536924) and rationale for combining with EGFR/HER2 inhibitors.

  Fei Huang;Ann Greer;Warren Hurlburt;Xia Han

  230
  Citations

• Beyond tamoxifen: the retinoid X receptor-selective ligand LGD1069 (TARGRETIN) causes complete regression of mammary carcinoma.

  Eric D. Bischoff;Marco M. Gottardis;Thomas E. Moon;Richard A. Heyman

  227
  Citations

• Synergistic methods and compositions for treating cancer

  Joan M. Carboni;Warren W. Hurlburt;Marco M. Gottardis

  223
  Citations

• Circumventing Tamoxifen Resistance in Breast Cancers Using Antiestrogens That Induce Unique Conformational Changes in the Estrogen Receptor

  Caroline E. Connor;John D. Norris;Gloria Broadwater;Timothy M. Willson

  199
  Citations

• High-level IGF1R expression is required for leukemia-initiating cell activity in T-ALL and is supported by Notch signaling

  Hind Medyouf;Samuel Gusscott;Hongfang Wang;Jen Chieh Tseng

  192
  Citations

• Discovery of a (1H-benzoimidazol-2-yl)-1H-pyridin-2-one (BMS-536924) inhibitor of insulin-like growth factor I receptor kinase with in vivo antitumor activity.

  Mark Wittman;Joan Carboni;Ricardo Attar;Balu Balasubramanian

  169
  Citations

• The androgen receptor can signal through Wnt/β-Catenin in prostate cancer cells as an adaptation mechanism to castration levels of androgens

  Liang Schweizer;Cheryl A Rizzo;Thomas E Spires;J Suso Platero

  166
  Citations

• Drug safety is a barrier to the discovery and development of new androgen receptor antagonists

  William R. Foster;Bruce D. Car;Hong Shi;Paul C. Levesque

  161
  Citations

• Estrogen stimulation and tamoxifen inhibition of leiomyoma cell growth in vitro and in vivo

  S R Howe;M M Gottardis;J I Everitt;C Walker

  153
  Citations