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Biology and Biochemistry

D-Index
55
Citations
11313
World Ranking
15023
National Ranking
6285

Overview

Karl E. Klose is affiliated with The University of Texas Health Science Center at San Antonio in the United States. Their research primarily spans the field of Biochemistry, Genetics, and Molecular Biology, with additional focus on subfields including Endocrinology, Molecular Biology, Immunology, Genetics, and Ecology.

The main topics addressed in their work cover Vibrio bacteria research studies, aquaculture disease management and microbiota, bacterial genetics and biotechnology, lipid membrane structure and behavior, bacterial biofilms and quorum sensing, Escherichia coli research studies, and bacteriophages and microbial interactions.

Recent publications illustrate the scope of the research, including:

  • "A peptide-binding domain shared with an Antarctic bacterium facilitates Vibrio cholerae human cell binding and intestinal colonization," 2023, Proceedings of the National Academy of Sciences
  • "Sugar-binding and split domain combinations in repeats-in-toxin adhesins from Vibrio cholerae and Aeromonas veronii mediate cell-surface recognition and hemolytic activities," 2024, mBio
  • "New Cloning Vectors to Facilitate Quick Allelic Exchange in Gram-Negative Bacteria," 2021, BioTechniques
  • "Natural Transformation in a Classical-Biotype Vibrio cholerae Strain," 2021, Applied and Environmental Microbiology
  • "The Vibrio Polar Flagellum: Structure and Regulation," 2023, Advances in Experimental Medicine and Biology

Karl E. Klose frequently collaborates with several coauthors, notably Cameron J. Lloyd, Shuaiqi Guo, Adrian Mejia-Santana, Venus Stanton, and Brett Kinrade. These collaborations have contributed to multiple joint publications.

Publication venues where Klose's work appears most often include mBio, Applied and Environmental Microbiology, Proceedings of the National Academy of Sciences, BioTechniques, and Advances in Experimental Medicine and Biology.

Best Publications

  • Vibrio cholerae and cholera: Out of the water and into the host

    Joachim Reidl;Karl E. Klose

  • A Francisella tularensis pathogenicity island required for intramacrophage growth

    Francis E. Nano;Na Zhang;Siobhán C. Cowley;Karl E. Klose

  • The absence of a flagellum leads to altered colony morphology, biofilm development and virulence in Vibrio cholerae O139.

    Paula I. Watnick;Crystal M. Lauriano;Karl E. Klose;Laura Croal

  • The phosphorylated form of the enhancer-binding protein NTRC has an ATPase activity that is essential for activation of transcription

    David S. Weiss;Jacques Batut;Karl E. Klose;John Keener

  • MglA regulates transcription of virulence factors necessary for Francisella tularensis intraamoebae and intramacrophage survival

    Crystal M. Lauriano;Jeffrey R. Barker;Sang Sun Yoon;Francis E. Nano

  • The novel sigma54- and sigma28-dependent flagellar gene transcription hierarchy of Vibrio cholerae.

    Michael G. Prouty;Nidia E. Correa;Karl E. Klose

  • Role of Vibrio polysaccharide (vps) genes in VPS production, biofilm formation and Vibrio cholerae pathogenesis.

    Jiunn C. N. Fong;Khalid A. Syed;Karl E. Klose;Fitnat H. Yildiz

  • Characterization of Vibrio cholerae O1 El Tor galU and galE Mutants: Influence on Lipopolysaccharide Structure, Colonization, and Biofilm Formation

    Jutta Nesper;Crystal M. Lauriano;Karl E. Klose;Dagmar Kapfhammer

  • The Francisella tularensis pathogenicity island encodes a secretion system that is required for phagosome escape and virulence

    Jeffrey R. Barker;Audrey Chong;Tara D. Wehrly;Jieh Juen Yu

  • The Virulence Regulatory Protein ToxR Mediates Enhanced Bile Resistance in Vibrio cholerae and Other Pathogenic Vibrio Species

    Daniele Provenzano;Darren A. Schuhmacher;Justin L. Barker;Karl E. Klose

  • Environmental Signals Modulate ToxT-Dependent Virulence Factor Expression in Vibrio cholerae

    Darren A. Schuhmacher;Karl E. Klose

  • The Vibrio cholerae Flagellar Regulatory Hierarchy Controls Expression of Virulence Factors

    Khalid Ali Syed;Sinem Beyhan;Nidia Correa;Jessica Queen

  • Distinct roles of an alternative sigma factor during both free-swimming and colonizing phases of the Vibrio cholerae pathogenic cycle.

    Karl E. Klose;John J. Mekalanos

  • DNA adenine methylase is essential for viability and plays a role in the pathogenesis of Yersinia pseudotuberculosis and Vibrio cholerae.

    Steven M. Julio;Douglas M. Heithoff;Daniele Provenzano;Karl E. Klose

  • Incidence, Virulence Factors, and Clonality among Clinical Strains of Non-O1, Non-O139 Vibrio cholerae Isolates from Hospitalized Diarrheal Patients in Kolkata, India

    S. Chatterjee;K. Ghosh;A. Raychoudhuri;G. Chowdhury

  • Prokaryotic enhancer-binding proteins reflect eukaryote-like modularity: the puzzle of nitrogen regulatory protein C.

    Anne K. North;Karl E. Klose;Kenneth M. Stedman;Sydney Kustu

  • Differential regulation of multiple flagellins in Vibrio cholerae

    Karl E. Klose;John J. Mekalanos

  • Zebrafish-Mycobacterium marinum model for mycobacterial pathogenesis.

    Michael G. Prouty;Nidia E. Correa;Lucia P. Barker;Pudur Jagadeeswaran

  • The Sodium-Driven Flagellar Motor Controls Exopolysaccharide Expression in Vibrio cholerae

    Crystal M. Lauriano;Chandradipa Ghosh;Nidia E. Correa;Karl E. Klose

  • Elucidation of a novel Vibrio cholerae lipid A secondary hydroxy-acyltransferase and its role in innate immune recognition

    Jessica V. Hankins;James A. Madsen;David K. Giles;Brandon M. Childers

Frequent Co-Authors

John J. Mekalanos
John J. Mekalanos Harvard Medical School
Bernard P. Arulanandam
Bernard P. Arulanandam The University of Texas at San Antonio
Edward T. Ryan
Edward T. Ryan Harvard University
Roberto Kolter
Roberto Kolter Harvard University
Stephen B. Calderwood
Stephen B. Calderwood Massachusetts General Hospital
David A. Low
David A. Low University of California, Santa Barbara

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