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Jennifer Southgate

Jennifer Southgate

D-Index & Metrics

Biology and Biochemistry

D-Index
63
Citations
13057
World Ranking
10297
National Ranking
783

Overview

Jennifer Southgate is affiliated with the University of York in the United Kingdom. Their research primarily spans the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with a focus on Surgery, Oncology, Molecular Biology, Urology, and Epidemiology as subfields of study.

Their work addresses a range of topics within biomedical research, notably:

  • Bladder and Urothelial Cancer Treatments
  • Tissue Engineering and Regenerative Medicine
  • Urological Disorders and Treatments
  • Cancer Genomics and Diagnostics
  • Epigenetics and DNA Methylation
  • Electrospun Nanofibers in Biomedical Applications
  • Polyomavirus and related diseases

Southgate has authored multiple papers including:

  • Induction of APOBEC3-mediated genomic damage in urothelium implicates BK polyomavirus (BKPyV) as a hit-and-run driver for bladder cancer, 2022, published in Oncogene
  • The Urothelial Transcriptomic Response to Interferon Gamma: Implications for Bladder Cancer Prognosis and Immunotherapy, 2022, published in Cancers
  • Procarcinogen Activation and Mutational Signatures Model the Initiation of Carcinogenesis in Human Urothelial Tissues In Vitro, 2020, published in European Urology
  • Augmentation of the insufficient tissue bed for surgical repair of hypospadias using acellular matrix grafts: A proof of concept study, 2021, published in Journal of Tissue Engineering
  • Does a Novel Mutagenic Process Target KMT2D Mutation in the Most Common First Event on the Path to Bladder Cancer?, 2020, published in European Urology

Their frequent coauthors include:

  • Simon C. Baker
  • Andrew S. Mason
  • Raphael G. Slip
  • Debora Morgante
  • Pontus Eriksson

Southgate's research has been published in several venues, with frequent contributions to:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • European Urology
  • American Journal Of Pathology
  • Oncogene
  • Cancers

Best Publications

  • Detection of melanoma cells in peripheral blood by means of reverse transcriptase and polymerase chain reaction.

    B. Smith;P. Selby;J. Southgate;K. Pittman

  • Detection of epithelial cancer cells in peripheral blood by reverse transcriptase-polymerase chain reaction.

    SA Burchill;MF Bradbury;K Pittman;J Southgate

  • Multistage carcinogenesis induced by ras and myc oncogenes in a reconstituted organ

    Timothy C. Thompson;Jennifer Southgate;Hartmut Land

  • Analysis of apoptosis in the preimplantation bovine embryo using TUNEL.

    A. T. Byrne;J. Southgate;D. R. Brison;H. J. Leese

  • EGFR as a potential therapeutic target for a subset of muscle-invasive bladder cancers presenting a basal-like phenotype

    Sandra Rebouissou;Isabelle Bernard-Pierrot;Aurélien de Reyniès;May-Linda Lepage

  • Characterisation of electrospun polystyrene scaffolds for three-dimensional in vitro biological studies.

    Simon C. Baker;Neil Atkin;Paul A. Gunning;Nick Granville

  • Development and characterisation of a full-thickness acellular porcine bladder matrix for tissue engineering.

    Fiona Bolland;Sotiris Korossis;Stacy-Paul Wilshaw;Eileen Ingham

  • Regional copy number–independent deregulation of transcription in cancer

    Nicolas Stransky;Céline Vallot;Fabien Reyal;Isabelle Bernard-Pierrot

  • The relationship between the mechanical properties and cell behaviour on PLGA and PCL scaffolds for bladder tissue engineering.

    Simon C. Baker;Géraldine Rohman;Jennifer Southgate;Neil R. Cameron

  • The epitheliome: agent-based modelling of the social behaviour of cells.

    D.C. Walker;J. Southgate;G. Hill;M. Holcombe

  • Cytokeratin expression patterns in normal and malignant urothelium: a review of the biological and diagnostic implications.

    J Southgate;P Harnden;L K Trejdosiewicz

  • Independent Component Analysis Uncovers the Landscape of the Bladder Tumor Transcriptome and Reveals Insights into Luminal and Basal Subtypes

    Anne Biton;Isabelle Bernard-Pierrot;Yinjun Lou;Clémentine Krucker

  • Agent-based computational modeling of wounded epithelial cell monolayers

    D.C. Walker;G. Hill;S.M. Wood;R.H. Smallwood

  • Role of PPAR γ and EGFR signalling in the urothelial terminal differentiation programme

    Claire L. Varley;Jens Stahlschmidt;Wen-Chun Lee;Julie Holder

  • Expression of cytokeratin 20 redefines urothelial papillomas of the bladder

    P Harnden;N Mahmood;J Southgate

  • Reconstitution of Human Urothelium From Monolayer Cultures

    S.D. Scriven;C. Booth;D.F.M. Thomas;L.K. Trejdosiewicz

  • Uroplakin gene expression by normal and neoplastic human urothelium.

    E. Dawn Lobban;Barbara A. Smith;Geoffrey D. Hall;Patricia Harnden

  • A biomimetic tissue from cultured normal human urothelial cells: analysis of physiological function

    W. R. Cross;I. Eardley;H. J. Leese;J. Southgate

  • Uroplakin gene expression in normal human tissues and locally advanced bladder cancer

    Jonathon Olsburgh;Patricia Harnden;Robert Weeks;Barbara Smith

  • p68 RNA helicase: identification of a nucleolar form and cloning of related genes containing a conserved intron in yeasts.

    RD Iggo;DJ Jamieson;Stuart Andrew MacNeill;J Southgate

Frequent Co-Authors

Peter Selby
Peter Selby University of Leeds
Eileen Ingham
Eileen Ingham University of Leeds
Henry J. Leese
Henry J. Leese Hull York Medical School
Adrian S. Woolf
Adrian S. Woolf University of Manchester
Rosamonde E. Banks
Rosamonde E. Banks University of Leeds
Jean Paul Thiery
Jean Paul Thiery National University of Singapore
David E. Barton
David E. Barton University College Dublin
Geoffrey Hall
Geoffrey Hall University of York
Neil R. Cameron
Neil R. Cameron Monash University

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