World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
71
Citations
20199
World Ranking
6577
National Ranking
3061

Overview

Brooke L. Fridley is affiliated with the University of Kansas in the United States and has contributed extensively to the fields of biochemistry, genetics, molecular biology, and medicine. Their research encompasses a broad range of subfields including molecular biology, oncology, cancer research, pulmonary and respiratory medicine, and immunology.

The scientist's work covers multiple topics within cancer biology and genomics. Key areas of focus include single-cell and spatial transcriptomics, cancer immunotherapy and biomarkers, cancer genomics and diagnostics, ovarian cancer diagnosis and treatment, gene expression and cancer classification, sarcoma diagnosis and treatment, and cancer-related molecular mechanisms research.

Fridley has collaborated frequently with several researchers in their field, including:

  • Alex C. Soupir
  • Oscar E. Ospina
  • Shelley S. Tworoger
  • Jonathan V. Nguyen
  • Carlos Moran Segura

The scientist's publication record shows a presence in a number of venues known for cancer and molecular biology research. Frequent publication venues comprise Cancer Research, bioRxiv (Cold Spring Harbor Laboratory), UNC Libraries, Cancer Epidemiology Biomarkers & Prevention, and Methods in Molecular Biology.

Among recent papers, notable publications include:

  • The harsh microenvironment in early breast cancer selects for a Warburg phenotype (2021), published in Proceedings of the National Academy of Sciences
  • Mendelian randomization analyses suggest a role for cholesterol in the development of endometrial cancer (2020), published in International Journal of Cancer
  • An evolutionary framework for treating pediatric sarcomas (2020), published in Cancer
  • Statistical and Bioinformatics Analysis of Data from Bulk and Single-Cell RNA Sequencing Experiments (2020), published in Methods in Molecular Biology
  • Challenges and Opportunities in the Statistical Analysis of Multiplex Immunofluorescence Data (2021), published in Cancers

Fridley has contributed to academic literature beyond articles, including the publication of the book Statistical Genomics in 2023 through Springer Science+Business Media.

Best Publications

  • Association between endometriosis and risk of histological subtypes of ovarian cancer: a pooled analysis of case-control studies.

    Celeste Leigh Pearce;Claire Templeman;Mary Anne Rossing;Alice Lee

  • Common Genetic Variation In Cellular Transport Genes and Epithelial Ovarian Cancer (EOC) Risk

    Ganna Chornokur;Hui-Yi Lin;Jonathan P. Tyrer;Kate Lawrenson

  • FKBP51 affects cancer cell response to chemotherapy by negatively regulating Akt.

    Huadong Pei;Liang Li;Brooke L. Fridley;Gregory D. Jenkins

  • Association Between BRCA1 and BRCA2 Mutations and Survival in Women with Invasive Epithelial Ovarian Cancer

    Kelly L. Bolton;Kelly L. Bolton;Georgia Chenevix-Trench;Cindy Goh;Siegal Sadetzki

  • Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer

    Stig E. Bojesen;Stig E. Bojesen;Karen A. Pooley;Sharon E. Johnatty;Jonathan Beesley

  • Hormone-receptor expression and ovarian cancer survival: an Ovarian Tumor Tissue Analysis consortium study

    Weiva Sieh;Martin Köbel;Teri A Longacre;David D Bowtell;David D Bowtell

  • Germline Mutations in the BRIP1, BARD1, PALB2, and NBN Genes in Women With Ovarian Cancer

    Susan J. Ramus;Honglin Song;Ed Dicks;Jonathan P. Tyrer

  • Identification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancer

    Catherine M Phelan;Karoline B Kuchenbaecker;Karoline B Kuchenbaecker;Jonathan P Tyrer;Siddhartha P Kar

  • GWAS meta-analysis and replication identifies three new susceptibility loci for ovarian cancer

    Paul D.P. Pharoah;Ya Yu Tsai;Susan J. Ramus;Catherine M. Phelan

  • A genome-wide association study identifies susceptibility loci for ovarian cancer at 2q31 and 8q24

    Ellen L Goode;Georgia Chenevix-Trench;Honglin Song;Susan J Ramus

  • Contribution of Germline Mutations in the RAD51B, RAD51C, and RAD51D Genes to Ovarian Cancer in the Population

    Honglin Song;Ed Dicks;Susan J. Ramus;Jonathan P. Tyrer

  • A genome-wide association study identifies a new ovarian cancer susceptibility locus on 9p22.2.

    Honglin Song;Susan J. Ramus;Jonathan Tyrer;Kelly L. Bolton;Kelly L. Bolton

  • Dose-Response Association of CD8(+) Tumor-Infiltrating Lymphocytes and Survival Time in High-Grade Serous Ovarian Cancer

    Ellen L. Goode;Matthew S. Block;Kimberly R. Kalli;Robert A. Vierkant

  • Common variants at 19p13 are associated with susceptibility to ovarian cancer.

    Kelly L Bolton;Kelly L Bolton;Jonathan Tyrer;Honglin Song;Susan J Ramus

  • Genome-wide association study of glioma and meta-analysis.

    Preetha Rajaraman;Beatrice S. Melin;Zhaoming Wang;Zhaoming Wang;Roberta McKean-Cowdin

  • Practical Guidelines for Assessing the Clinical Significance of Health-Related Quality of Life Changes within Clinical Trials

    Jeff A. Sloan;Tara Symonds;Delfino Vargas-Chanes;Brooke Fridley

  • Obesity and risk of ovarian cancer subtypes: evidence from the Ovarian Cancer Association Consortium

    Catherine M Olsen;Christina M Nagle;David C Whiteman;Roberta Ness

  • Identification of nine new susceptibility loci for endometrial cancer

    Tracy A. O'Mara;Dylan M. Glubb;Frédéric Amant;Daniela Annibali

  • Host genetic variation contributes to phenotypic diversity in myeloproliferative disorders.

    Animesh Dev Pardanani;Brooke L. Fridley;Terra L. Lasho;D. Gary Gilliland;D. Gary Gilliland

  • ABCA Transporter Gene Expression and Poor Outcome in Epithelial Ovarian Cancer

    Ellen L. Hedditch;Bo Gao;Amanda J. Russell;Yi Lu

Frequent Co-Authors

Ellen L. Goode
Ellen L. Goode Mayo Clinic
Joellen M. Schildkraut
Joellen M. Schildkraut University of Virginia
Peter A. Fasching
Peter A. Fasching University of Erlangen-Nuremberg
Graham G. Giles
Graham G. Giles University of Melbourne
Susan J. Ramus
Susan J. Ramus University of New South Wales
Jenny Chang-Claude
Jenny Chang-Claude German Cancer Research Center
Paul D.P. Pharoah
Paul D.P. Pharoah University of Cambridge
Catherine M. Phelan
Catherine M. Phelan University of South Florida

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