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D-Index & Metrics

Genetics

D-Index
54
Citations
16606
World Ranking
3620
National Ranking
1569

Research.com Recognitions

  • 2020 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Hiten D. Madhani is affiliated with the University of California, San Francisco in the United States. They have an extensive body of work primarily situated within the fields of Biochemistry, Genetics and Molecular Biology, and Medicine, with a focus on several interconnected subfields.

Their research spans molecular biology, epidemiology, plant science, infectious diseases, and immunology. These subfields underpin their investigation into notable scientific topics including fungal infections and studies, RNA and protein synthesis mechanisms, antifungal resistance and susceptibility, RNA modifications and cancer, plant-microbe interactions and immunity, RNA research and splicing, and legume nitrogen-fixing symbiosis.

Their recent published papers illustrate this focus and include:

  • Evolutionary Persistence of DNA Methylation for Millions of Years after Ancient Loss of a De Novo Methyltransferase, 2020, Cell
  • Secreted fungal virulence effector triggers allergic inflammation via TLR4, 2022, Nature
  • Short homology-directed repair using optimized Cas9 in the pathogen Cryptococcus neoformans enables rapid gene deletion and tagging, 2021, Genetics
  • Quantitative global studies reveal differential translational control by start codon context across the fungal kingdom, 2020, Nucleic Acids Research
  • Coupling of spliceosome complexity to intron diversity, 2021, Current Biology

Hiten D. Madhani has collaborated frequently with several researchers, indicating recurring partnerships in their research endeavors. These include Manning Y. Huang, Michael J. Boucher, Beiduo Rao, John R. Yates, and Susan Lei.

Their work appears regularly in several scientific venues, particularly bioRxiv (Cold Spring Harbor Laboratory), Cell, Molecular Cell, Journal of Medicinal Chemistry, and G3 Genes Genomes Genetics.

Among accolades, they were recognized as a Fellow of the American Association for the Advancement of Science (AAAS) in 2020.

Best Publications

  • Conserved Histone Variant H2A.Z Protects Euchromatin from the Ectopic Spread of Silent Heterochromatin

    Marc D. Meneghini;Michelle Wu;Hiten D. Madhani

  • Histone variant H2A.Z marks the 5' ends of both active and inactive genes in euchromatin.

    Ryan M. Raisner;Paul D. Hartley;Marc D. Meneghini;Marie Z. Bao

  • Signals for ribosomal frameshifting in the Rous sarcoma virus gag-pol region.

    Tyler Jacks;Hiten D. Madhani;Frank R. Masiarz;Harold E. Varmus

  • A Protein Complex Containing the Conserved Swi2/Snf2-Related ATPase Swr1p Deposits Histone Variant H2A.Z into Euchromatin

    Michael. S Kobor;Shivkumar Venkatasubrahmanyam;Marc D Meneghini;Jennifer W Gin

  • Unconventional Rac-GEF activity is mediated through the Dock180–ELMO complex

    Enrico Brugnera;Lisa Haney;Cynthia Grimsley;Mingjian Lu

  • Ten principles of heterochromatin formation and function.

    Robin C. Allshire;Hiten D. Madhani

  • A comprehensive strategy enabling high-resolution functional analysis of the yeast genome

    David K Breslow;Dale M Cameron;Sean R Collins;Maya Schuldiner

  • MAP Kinases with Distinct Inhibitory Functions Impart Signaling Specificity during Yeast Differentiation

    Hiten D. Madhani;Cora A. Styles;Gerald R. Fink

  • A novel base-pairing interaction between U2 and U6 snRNAs suggests a mechanism for the catalytic activation of the spliceosome.

    Hiten D. Madhani;Christine Guthrie

  • Combinatorial control required for the specificity of yeast MAPK signaling.

    Hiten D. Madhani;Gerald R. Fink

  • A Conserved RING Finger Protein Required for Histone H2B Monoubiquitination and Cell Size Control.

    William W. Hwang;Shivkumar Venkatasubrahmanyam;Alexandra G. Ianculescu;Amy Tong

  • MAP kinase and cAMP filamentation signaling pathways converge on the unusually large promoter of the yeast FLO11 gene

    Steffen Rupp;Eric Summers;Hsiu‐Jung Lo;Hiten Madhani

  • Dynamic RNA-RNA Interactions in the Spliceosome

    Hiten D. Madhani;Christine Guthrie

  • Systematic genetic analysis of virulence in the human fungal pathogen Cryptococcus neoformans

    Oliver W. Liu;Cheryl D. Chun;Eric D. Chow;Changbin Chen

  • Mechanisms that specify promoter nucleosome location and identity

    Paul D. Hartley;Hiten D. Madhani

  • The riddle of MAP kinase signaling specificity

    Hiten D Madhani;Gerald R Fink

  • The control of filamentous differentiation and virulence in fungi

    Hiten D Madhani;Gerald R Fink

  • Chromodomain-mediated oligomerization of HP1 suggests a nucleosome-bridging mechanism for heterochromatin assembly

    Daniele Canzio;Evelyn Y. Chang;Smita Shankar;Kristopher M. Kuchenbecker

  • Principles of MAP Kinase Signaling Specificity in Saccharomyces cerevisiae

    Monica A. Schwartz;Hiten D. Madhani

  • A Link between Virulence and Homeostatic Responses to Hypoxia during Infection by the Human Fungal Pathogen Cryptococcus neoformans

    Cheryl D Chun;Oliver W Liu;Hiten D Madhani

Frequent Co-Authors

John R. Yates
John R. Yates Scripps Research Institute
Geeta J. Narlikar
Geeta J. Narlikar University of California, San Francisco
Christina A. Cuomo
Christina A. Cuomo Broad Institute
Kevan M. Shokat
Kevan M. Shokat University of California, San Francisco
Charles S. Craik
Charles S. Craik University of California, San Francisco
Martin Kampmann
Martin Kampmann University of California, San Francisco
Jonathan K. Pritchard
Jonathan K. Pritchard Stanford University
Joseph L. DeRisi
Joseph L. DeRisi University of California, San Francisco
Nevan J. Krogan
Nevan J. Krogan University of California, San Francisco

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