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D-Index & Metrics

Microbiology

D-Index
68
Citations
17399
World Ranking
2150
National Ranking
9

Overview

Helmut Wachter was affiliated with the University of Innsbruck in Austria. Their work contributed to multiple interdisciplinary fields intersecting medicine, biochemistry, genetics, and molecular biology, with an emphasis on public health, environmental and occupational health, molecular biology, biochemistry, clinical psychology, and general health professions.

Their research primarily addressed topics such as:

  • Palliative Care and End-of-Life Issues
  • Lipid metabolism and biosynthesis
  • Metabolomics and Mass Spectrometry Studies
  • Peroxisome Proliferator-Activated Receptors
  • Organ Donation and Transplantation
  • Patient Dignity and Privacy
  • Ethics in medical practice

Wachter published extensively in various scientific venues. Frequent publication venues included:

  • Medicine
  • Geburtshilfe und Frauenheilkunde
  • DOAJ (DOAJ: Directory of Open Access Journals)
  • Proceedings of the National Academy of Sciences
  • Trends in biotechnology

Their recent notable papers spanned a range of biomedical topics and appeared in respected journals. These included:

  • The TMEM189 gene encodes plasmanylethanolamine desaturase which introduces the characteristic vinyl ether double bond into plasmalogens (2020), Proceedings of the National Academy of Sciences
  • Geneva Statement on Heritable Human Genome Editing: The Need for Course Correction (2020), Trends in biotechnology
  • When the genome bluffs: a tandem duplication event during generation of a novel Agmo knockout mouse model fools routine genotyping (2021), Cell & Bioscience
  • Psychosocial and bioethical challenges and developments for the future of vascularized composite allotransplantation: A scoping review and viewpoint of recent developments and clinical experiences in the field of vascularized composite allotransplantation (2022), Frontiers in Psychology
  • Alterations in ether lipid metabolism and the consequences for the mouse lipidome (2023), Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids

Throughout their career, Wachter collaborated frequently with the following coauthors:

  • Ernst R. Werner
  • S. Sailer
  • Katharina Lackner
  • Georg Golderer
  • Katrin Watschinger

The breadth of Wachter's work reflected multiple core fields including medicine and biochemistry, genetics, and molecular biology. Their publication record showed a significant focus on health-related public and occupational concerns, molecular mechanisms in biology, and ethical aspects of medical practice.

Best Publications

  • Immune response-associated production of neopterin. Release from macrophages primarily under control of interferon-gamma.

    C Huber;J R Batchelor;D Fuchs;A Hausen

  • Neopterin as a marker for activated cell-mediated immunity: Application in HIV infection

    Dietmar Fuchs;Arno Hausen;Gilbert Reibnegger;Ernst R. Werner

  • Brain nitric oxide synthase is a biopterin- and flavin-containing multi-functional oxido-reductase

    Bernd Mayer;Mathias John;Burghard Heinzel;Ernst R. Werner

  • Neopterin as marker for activation of cellular immunity: immunologic basis and clinical application.

    Helmut Wachter;Dietmar Fuchs;Arno Hausen;Gilbert Reibnegger

  • Soluble receptors for tumour necrosis factor in clinical laboratory diagnosis

    Antonio Diez‐Ruiz;Gernot P. Tilz;Robert Zangerle;Gabriele Baier‐Bitterlich

  • The role of neopterin as a monitor of cellular immune activation in transplantation, inflammatory, infectious, and malignant diseases.

    Dietmar Fuchs;Günter Weiss;Gilbert Reibnegger;Helmut Wachter

  • Tetrahydrobiopterin biosynthetic activities in human macrophages, fibroblasts, THP-1, and T 24 cells. GTP-cyclohydrolase I is stimulated by interferon-gamma, and 6-pyruvoyl tetrahydropterin synthase and sepiapterin reductase are constitutively present.

    E R Werner;G Werner-Felmayer;D Fuchs;A Hausen

  • Protein kinase C-theta isoenzyme selective stimulation of the transcription factor complex AP-1 in T lymphocytes.

    G Baier-Bitterlich;F Uberall;B Bauer;F Fresser

  • Neopterin, biochemistry and clinical use as a marker for cellular immune reactions.

    Dietmar Fuchs;Günter Weiss;Helmut Wachter

  • HUMAN MACROPHAGES DEGRADE TRYPTOPHAN UPON INDUCTION BY INTERFERON GAMMA

    Ernst R. Werner;Gabriele Bitterlich;Dietmar Fuchs;Arno Hausen

  • Linkage of cell-mediated immunity to iron metabolism

    Günter Weiss;Helmut Wachter;Dietmar Fuchs

  • Parallel induction of tetrahydrobiopterin biosynthesis and indoleamine 2,3-dioxygenase activity in human cells and cell lines by interferon-gamma.

    E R Werner;G Werner-Felmayer;D Fuchs;A Hausen

  • Characteristics of interferon induced tryptophan metabolism in human cells in vitro.

    Gabriele Werner-Felmayer;Ernst Robert Werner;Dietmar Fuchs;Arno Hausen

  • Neopterin modulates toxicity mediated by reactive oxygen and chloride species

    Günter Weiss;Dietmar Fuchs;Arno Hausen;Gilbert Reibnegger

  • Neopterin as a new biochemical marker for diagnosis of allograft rejection. Experience based upon evaluation of 100 consecutive cases.

    R. Margreiter;D. Fuchs;A. Hausen;C. Huber

  • Immune activation and the anaemia associated with chronic inflammatory disorders

    Dietmar Fuchs;Arno Hausen;Gilbert Reibnegger;Ernst R. Werner

  • Increased concentrations of neopterin in carotid atherosclerosis

    Günter Weiss;Johann Willeit;Stefan Kiechl;Dietmar Fuchs

  • Increased endogenous interferon-gamma and neopterin correlate with increased degradation of tryptophan in human immunodeficiency virus type 1 infection.

    Dietmar Fuchs;Arnulf A. Möller;Gilbert Reibnegger;Ernst R. Werner

  • Urinary neopterin reflects clinical activity in patients with rheumatoid arthritis.

    Gilbert Reibnegger;Dietmar Egg;Dietmar Fuchs;Robert Günther

  • Neopterin concentrations in cerebrospinal fluid and serum of individuals infected with HIV-1.

    Dietmar Fuchs;Francesca Chiodi;Jan Albert;Birgitta Asjö

  • Tumour necrosis factor-alpha and lipopolysaccharide enhance interferon-induced tryptophan degradation and pteridine synthesis in human cells.

    Gabriele Werner-Felmayer;Ernst Robert Werner;Dietmar Fuchs;Arno Hausen

  • Immune activation and decreased tryptophan in patients with HIV-1 infection.

    D. Fuchs;A. Forsman;L. Hagberg;M. Larsson

  • Endogenous release of interferon-gamma and diminished response of peripheral blood mononuclear cells to antigenic stimulation

    Dietmar Fuchs;Miroslav Malkovsky;Gilbert Reibnegger;Ernst R. Werner

  • Neopterin formation and tryptophan degradation by a human myelomonocytic cell line (THP-1) upon cytokine treatment.

    Gabriele Werner-Felmayer;Ernst Robert Werner;Dietmar Fuchs;Arno Hausen

  • Tetrahydrobiopterin and cytokines.

    Ernst R. Werner;Gabriele Werner-Felmayer;Helmut Wachter

  • Induction of inducible nitric oxide synthase expression by neopterin in vascular smooth muscle cells

    Wolfgang Schobersberger;Georg Hoffmann;Jfirgen Grote;Helmut Wachter

  • Tryptophan degradation in patients infected by human immunodeficiency virus.

    Ernst R. Werner;Dietmar Fuchs;Arno Hausen;Hans Jaeger

  • Approach to define "normal aging" in man. Immune function, serum lipids, lipoproteins and neopterin levels.

    Gilbert Reibnegger;Lukas A. Huber;Günther Jürgens;Diether Schönitzer

  • HIV and HIV-infected cells differentially activate the human complement system independent of antibody.

    B.M. Sölder;T.F. Schulz;P. Hengster;J. Löwer

  • Serum soluble markers of immune activation and disease activity in systemic lupus erythematosus

    Mikhail Y Samsonov;Gernot P Tilz;Olga Egorova;Gilbert Reibnegger

Frequent Co-Authors

Dietmar Fuchs
Dietmar Fuchs Innsbruck Medical University
Gilbert Reibnegger
Gilbert Reibnegger Medical University of Graz
Ernst R. Werner
Ernst R. Werner Innsbruck Medical University
Gabriele Werner-Felmayer
Gabriele Werner-Felmayer Innsbruck Medical University
Günter Weiss
Günter Weiss Innsbruck Medical University
Manfred P. Dierich
Manfred P. Dierich Innsbruck Medical University
Wolfgang Pfleiderer
Wolfgang Pfleiderer University of Konstanz
Thomas F. Schulz
Thomas F. Schulz Hannover Medical School
Josef Pfeilschifter
Josef Pfeilschifter Goethe University Frankfurt
Lars Hagberg
Lars Hagberg Sahlgrenska University Hospital

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