World's Best Scientists 2026 revealed!
Gabriele Werner-Felmayer

Gabriele Werner-Felmayer

D-Index & Metrics

Biology and Biochemistry

D-Index
54
Citations
11355
World Ranking
15559
National Ranking
142

Overview

What is she best known for?

The fields of study she is best known for:

  • Enzyme
  • Gene
  • Internal medicine

Her scientific interests lie mostly in Biochemistry, Tetrahydrobiopterin, Neopterin, Interferon gamma and Cell culture. Biochemistry is represented through her Cofactor, ATP synthase, Sepiapterin reductase and Biopterin research. Her Tetrahydrobiopterin study results in a more complete grasp of Nitric oxide.

Her biological study spans a wide range of topics, including Tumor necrosis factor alpha, Toxicity, Hydrogen peroxide and Cytotoxicity. Gabriele Werner-Felmayer has researched Interferon gamma in several fields, including Stage and Cell mediated immunity. Her Cell culture research incorporates themes from Receptor, Cell adhesion molecule, Guanosine, Regulation of gene expression and Effector.

Her most cited work include:

  • Nitric oxide synthase is induced in sporulation of Physarum polycephalum (366 citations)
  • Tetrahydrobiopterin biosynthetic activities in human macrophages, fibroblasts, THP-1, and T 24 cells. GTP-cyclohydrolase I is stimulated by interferon-gamma, and 6-pyruvoyl tetrahydropterin synthase and sepiapterin reductase are constitutively present. (219 citations)
  • Parallel induction of tetrahydrobiopterin biosynthesis and indoleamine 2,3-dioxygenase activity in human cells and cell lines by interferon-gamma. (181 citations)

What are the main themes of her work throughout her whole career to date?

Gabriele Werner-Felmayer mainly investigates Biochemistry, Tetrahydrobiopterin, Neopterin, Nitric oxide synthase and Immunology. Her research related to Enzyme, Alkylglycerol monooxygenase, ATP synthase, Sepiapterin reductase and Intracellular might be considered part of Biochemistry. Her research on Tetrahydrobiopterin often connects related areas such as Molecular biology.

Her research integrates issues of Cell culture, In vitro, Interferon gamma and Stimulation in her study of Neopterin. Her research investigates the link between Cell culture and topics such as Microbiology that cross with problems in Lipopolysaccharide. While the research belongs to areas of Nitric oxide synthase, Gabriele Werner-Felmayer spends her time largely on the problem of Pharmacology, intersecting her research to questions surrounding Reperfusion injury.

She most often published in these fields:

  • Biochemistry (33.76%)
  • Tetrahydrobiopterin (32.48%)
  • Neopterin (21.66%)

What were the highlights of her more recent work (between 2010-2021)?

  • Biochemistry (33.76%)
  • Tetrahydrobiopterin (32.48%)
  • Alkylglycerol monooxygenase (4.46%)

In recent papers she was focusing on the following fields of study:

Her primary areas of study are Biochemistry, Tetrahydrobiopterin, Alkylglycerol monooxygenase, Enzyme and Genetics. Her Fatty aldehyde, Dehydrogenase and Biosynthesis study in the realm of Biochemistry interacts with subjects such as Sjögren–Larsson syndrome and Plasmanylethanolamine desaturase. Nitric oxide synthase and Cofactor are the two main areas of interest in her Tetrahydrobiopterin studies.

Nitric oxide synthase is the subject of her research, which falls under Nitric oxide. The study incorporates disciplines such as Biopterin, Phenylalanine hydroxylase, Escherichia coli, Peptide sequence and Lipid metabolism in addition to Alkylglycerol monooxygenase. Her work deals with themes such as High-performance liquid chromatography, Chromatography and Acetic acid, which intersect with Enzyme.

Between 2010 and 2021, her most popular works were:

  • The Physarum polycephalum Genome Reveals Extensive Use of Prokaryotic Two-Component and Metazoan-Type Tyrosine Kinase Signaling. (55 citations)
  • Tetrahydrobiopterin and alkylglycerol monooxygenase substantially alter the murine macrophage lipidome (34 citations)
  • Cuticle Integrity and Biogenic Amine Synthesis in Caenorhabditis elegans Require the Cofactor Tetrahydrobiopterin (BH4) (18 citations)

In her most recent research, the most cited papers focused on:

  • Enzyme
  • Gene
  • Internal medicine

Gabriele Werner-Felmayer mostly deals with Biochemistry, Tetrahydrobiopterin, Alkylglycerol monooxygenase, Gene and Lipid metabolism. Gabriele Werner-Felmayer frequently studies issues relating to Toxicity and Biochemistry. Her Tetrahydrobiopterin study improves the overall literature in Enzyme.

Her Enzyme research includes themes of Peptide sequence, Alanine and Phenylalanine hydroxylase. Her study in the field of Biosynthesis also crosses realms of Plasmanylethanolamine desaturase and Plasmanylethanolamine desaturase activity. Her study in Lipid metabolism is interdisciplinary in nature, drawing from both Nitric oxide synthase, Biopterin, Caenorhabditis elegans and Lipidomics.

Best Publications

  • Prognostic value of indoleamine 2,3-dioxygenase expression in colorectal cancer: effect on tumor-infiltrating T cells.

    Gerald Brandacher;Alexander Perathoner;Ruth Ladurner;Ruth Ladurner;Stefan Schneeberger

  • Iron regulates nitric oxide synthase activity by controlling nuclear transcription.

    Gtinter Weiss;Gabriele Werner-Felmayer;Ernst R. Werner;Kurt Grünewald

  • L-ascorbic acid potentiates endothelial nitric oxide synthesis via a chemical stabilization of tetrahydrobiopterin.

    Regine Heller;Anett Unbehaun;Berit Schellenberg;Bernd Mayer

  • Translational regulation via iron-responsive elements by the nitric oxide/NO-synthase pathway

    G Weiss;B Goossen;W Doppler;D Fuchs

  • Tetrahydrobiopterin alters superoxide and nitric oxide release in prehypertensive rats.

    F Cosentino;S Patton;L V d'Uscio;E R Werner

  • Unipolar membrane association of Dishevelled mediates Frizzled planar cell polarity signaling

    Jeffrey D. Axelrod

  • Tetrahydrobiopterin-dependent formation of nitrite and nitrate in murine fibroblasts.

    G Werner-Felmayer;E R Werner;D Fuchs;A Hausen

  • Tetrahydrobiopterin biosynthetic activities in human macrophages, fibroblasts, THP-1, and T 24 cells. GTP-cyclohydrolase I is stimulated by interferon-gamma, and 6-pyruvoyl tetrahydropterin synthase and sepiapterin reductase are constitutively present.

    E R Werner;G Werner-Felmayer;D Fuchs;A Hausen

  • Pteridine biosynthesis in human endothelial cells. Impact on nitric oxide-mediated formation of cyclic GMP

    G Werner-Felmayer;E R Werner;D Fuchs;A Hausen

  • Parallel induction of tetrahydrobiopterin biosynthesis and indoleamine 2,3-dioxygenase activity in human cells and cell lines by interferon-gamma.

    E R Werner;G Werner-Felmayer;D Fuchs;A Hausen

  • Characteristics of interferon induced tryptophan metabolism in human cells in vitro.

    Gabriele Werner-Felmayer;Ernst Robert Werner;Dietmar Fuchs;Arno Hausen

  • International validation of novel pyrogen tests based on human monocytoid cells.

    Sebastian Hoffmann;Anja Peterbauer;Stefanie Schindler;Stefan Fennrich

  • Neopterin modulates toxicity mediated by reactive oxygen and chloride species

    Günter Weiss;Dietmar Fuchs;Arno Hausen;Gilbert Reibnegger

  • Tetrahydrobiopterin biosynthesis, utilization and pharmacological effects.

    G. Werner-Felmayer;G. Golderer;E. R. Werner

  • Interferon-gamma concentrations are increased in sera from individuals infected with human immunodeficiency virus type 1.

    Fuchs D;Hausen A;Reibnegger G;Werner Er

  • Iron modulates interferon-gamma effects in the human myelomonocytic cell line THP-1.

    Weiss G;Fuchs D;Hausen A;Reibnegger G

  • Immune activation and the anaemia associated with chronic inflammatory disorders

    Dietmar Fuchs;Arno Hausen;Gilbert Reibnegger;Ernst R. Werner

  • Tetrahydrobiopterin and nitric oxide: mechanistic and pharmacological aspects.

    Ernst R. Werner;Antonius C.F. Gorren;Regine Heller;Gabriele Werner-Felmayer

  • Increased endogenous interferon-gamma and neopterin correlate with increased degradation of tryptophan in human immunodeficiency virus type 1 infection.

    Dietmar Fuchs;Arnulf A. Möller;Gilbert Reibnegger;Ernst R. Werner

  • Tumour necrosis factor-alpha and lipopolysaccharide enhance interferon-induced tryptophan degradation and pteridine synthesis in human cells.

    Gabriele Werner-Felmayer;Ernst Robert Werner;Dietmar Fuchs;Arno Hausen

Frequent Co-Authors

Ernst R. Werner
Ernst R. Werner Innsbruck Medical University
Dietmar Fuchs
Dietmar Fuchs Innsbruck Medical University
Gilbert Reibnegger
Gilbert Reibnegger Medical University of Graz
Helmut Wachter
Helmut Wachter University of Innsbruck
Günter Weiss
Günter Weiss Innsbruck Medical University
Bernd Mayer
Bernd Mayer University of Graz
Albin Hermetter
Albin Hermetter Graz University of Technology
Raimund Margreiter
Raimund Margreiter Innsbruck Medical University
Kurt Schmidt
Kurt Schmidt University of Graz
Christian Bogdan
Christian Bogdan University of Erlangen-Nuremberg

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Exploring a career in Biology or Biochemistry opens doors to several related fields, many of which now offer flexible online learning options. For those interested in a science-focused curriculum, an online biology degree provides a strong foundation in life sciences, equipping students for roles in laboratories, research, or teaching.

Healthcare is a popular pathway, and an online associate rn programs can help you become a registered nurse, combining biology coursework with hands-on clinical experience. If you're interested in helping others achieve better health through food and nutrition, consider pursuing a nutritionist degree online. This path focuses on biochemistry and its impact on diet and wellness.

For professionals aiming for leadership roles in healthcare, earning a degree from cahme accredited mha programs prepares you for hospital administration and healthcare management careers. These diverse online degree options provide flexibility and open multiple career avenues for biology and biochemistry students.

Best Scientists Citing Gabriele Werner-Felmayer

Trending Scientists

Recently Published Articles