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Biology and Biochemistry

D-Index
74
Citations
18765
World Ranking
5619
National Ranking
2669

Overview

Harry Ostrer is affiliated with the Albert Einstein College of Medicine in the United States. Their research primarily spans the fields of Biochemistry, Genetics and Molecular Biology, as well as Medicine. Within these fields, the scientist has a notable focus on subfields including Genetics, Molecular Biology, Oncology, Cancer Research, and Surgery.

The core topics of Harry Ostrer's work include studies on BRCA gene mutations in cancer, PARP inhibition in cancer therapy, cancer genomics and diagnostics, inflammatory bowel disease, forensic and genetic research, genetic diversity and population structure, and investigations into race, genetics, and society.

Ostrer's recent scholarly contributions encompass several research papers published in prominent venues. Notable papers include:

  • Large-scale sequencing identifies multiple genes and rare variants associated with Crohn's disease susceptibility, 2022, Nature Genetics
  • Genome-wide data from medieval German Jews show that the Ashkenazi founder event pre-dated the 14th century, 2022, Cell
  • Novel ultra-rare exonic variants identified in a founder population implicate cadherins in schizophrenia, 2021, Neuron
  • Identifying high-impact variants and genes in exomes of Ashkenazi Jewish inflammatory bowel disease patients, 2023, Nature Communications
  • Sequencing of over 100,000 individuals identifies multiple genes and rare variants associated with Crohns disease susceptibility, 2021, bioRxiv (Cold Spring Harbor Laboratory)

Harry Ostrer frequently collaborates with other researchers, with co-authors appearing regularly across multiple publications. These frequent collaborators include Gil Atzmon, Nir Barzilai, Inga Peter, Neelima Vidula, and Senthil Damodaran.

The researcher's work is often published in venues such as bioRxiv (Cold Spring Harbor Laboratory), Cancer Research, Journal of Clinical Oncology, Nature Genetics, and Cell. Among these, bioRxiv hosts the highest number of their articles, followed by Cancer Research.

Best Publications

  • Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci

    Fredrick R. Schumacher;Ali Amin Al Olama;Sonja I. Berndt;Sara Benlloch

  • Familial colorectal cancer in Ashkenazim due to a hypermutable tract in APC

    Steven J. Laken;Gloria M. Petersen;Stephen B. Gruber;Carole Oddoux

  • Mutations in the Connexin 26 Gene (GJB2) among Ashkenazi Jews with Nonsyndromic Recessive Deafness

    Morell Rj;Kim Hj;Hood Lj;Goforth L

  • Dating the Origin of the CCR5-Δ32 AIDS-Resistance Allele by the Coalescence of Haplotypes

    J. Claiborne Stephens;David E. Reich;David B. Goldstein;Hyoung Doo Shin

  • Shortened telomeres in clonally expanded CD28-CD8+ T cells imply a replicative history that is distinct from their CD28+CD8+ counterparts.

    Joanita Monteiro;Franak Batliwalla;Harry Ostrer;Peter K. Gregersen

  • The carrier frequency of the BRCA2 6174delT mutation among Ashkenazi Jewish individuals is approximately 1

    C. Oddoux;J. P. Struewing;C. M. Clayton;S. Neuhausen

  • Dominant and recessive deafness caused by mutations of a novel gene, TMC1 , required for cochlear hair-cell function

    Kiyoto Kurima;Linda M. Peters;Yandan Yang;Saima Riazuddin

  • Genome-wide patterns of population structure and admixture among Hispanic/Latino populations

    Katarzyna Bryc;Christopher Velez;Tatiana Karafet;Andres Moreno-Estrada;Andres Moreno-Estrada

  • Abnormal RNA processing due to the exon mutation of beta E-globin gene.

    Stuart H. Orkin;Haig H. Kazazian;Stylianos E. Antonarakis;Harry Ostrer

  • Jewish and Middle Eastern non-Jewish populations share a common pool of Y-chromosome biallelic haplotypes

    M. F. Hammer;A. J. Redd;E. T. Wood;M. R. Bonner

  • Mutation and haplotype studies of familial Mediterranean fever reveal new ancestral relationships and evidence for a high carrier frequency with reduced penetrance in the Ashkenazi Jewish population.

    Ivona Aksentijevich;Yelizaveta Torosyan;Jonathan Samuels;Michael Centola

  • Trans-ancestry genome-wide association meta-analysis of prostate cancer identifies new susceptibility loci and informs genetic risk prediction

    David V. Conti;Burcu F. Darst;Lilit C. Moss;Edward J. Saunders

  • SRY, SOX9, and DAX1 expression patterns during human sex determination and gonadal development

    N.A Hanley;D.M Hagan;M Clement-Jones;S.G Ball

  • Functional variants in the LRRK2 gene confer shared effects on risk for Crohn's disease and Parkinson's disease.

    Ken Y. Hui;Heriberto Fernandez-Hernandez;Jianzhong Hu;Adam Schaffner

  • Abraham's Children in the Genome Era: Major Jewish Diaspora Populations Comprise Distinct Genetic Clusters with Shared Middle Eastern Ancestry

    Gil Atzmon;Li Hao;Itsik Pe'er;Christopher Velez

  • The history of African gene flow into Southern Europeans, Levantines, and Jews.

    Priya Moorjani;Nick Patterson;Joel N. Hirschhorn;Joel N. Hirschhorn;Joel N. Hirschhorn;Alon Keinan

  • DREAM4: Combining Genetic and Dynamic Information to Identify Biological Networks and Dynamical Models

    Alex Greenfield;Aviv Madar;Harry Ostrer;Richard Bonneau;Richard Bonneau

  • A genetic profile of contemporary Jewish populations.

    Harry Ostrer

  • Expression of steroidogenic factor 1 and Wilms' tumour 1 during early human gonadal development and sex determination.

    N.A. Hanley;N.A. Hanley;S.G. Ball;M. Clement-Jones;D.M. Hagan

  • A Genome-Wide Scan of Ashkenazi Jewish Crohn's Disease Suggests Novel Susceptibility Loci

    Eimear E. Kenny;Itsik Pe'er;Amir Karban;Laurie Ozelius

Frequent Co-Authors

Gil Atzmon
Gil Atzmon Albert Einstein College of Medicine
Richard G. Stock
Richard G. Stock Icahn School of Medicine at Mount Sinai
Alison M. Dunning
Alison M. Dunning University of Cambridge
David E. Neal
David E. Neal University of Cambridge
Catharine M L West
Catharine M L West University of Manchester
Kenneth Offit
Kenneth Offit Memorial Sloan Kettering Cancer Center
Judy H. Cho
Judy H. Cho Icahn School of Medicine at Mount Sinai
Itsik Pe'er
Itsik Pe'er Columbia University
Todd Lencz
Todd Lencz Feinstein Institute for Medical Research
Graham G. Giles
Graham G. Giles University of Melbourne

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