Hai-Hui "Howard" Xue

Best Publications

• Defining CD8 + T cells that provide the proliferative burst after PD-1 therapy

  Se Jin Im;Masao Hashimoto;Michael Y Gerner;Michael Y Gerner;Junghwa Lee

  2060
  Citations

• Differentiation and persistence of memory CD8+ T cells depend on T cell factor 1

  Xinyuan Zhou;Shuyang Yu;Dong-Mei Zhao;John T. Harty

  749
  Citations

• LEF-1 and TCF-1 orchestrate T(FH) differentiation by regulating differentiation circuits upstream of the transcriptional repressor Bcl6.

  Youn Soo Choi;Jodi A. Gullicksrud;Shaojun Xing;Zhouhao Zeng

  350
  Citations

• Repetitive Antigen Stimulation Induces Stepwise Transcriptome Diversification but Preserves a Core Signature of Memory CD8+ T Cell Differentiation

  Thomas C. Wirth;Hai-Hui Xue;Deepa Rai;Jaime T. Sabel

  313
  Citations

• TCF-1 upregulation identifies early innate lymphoid progenitors in the bone marrow

  Qi Yang;Fengyin Li;Christelle Harly;Shaojun Xing

  298
  Citations

• IL-2 negatively regulates IL-7 receptor α chain expression in activated T lymphocytes

  Hai-Hui Xue;Panu E. Kovanen;Cynthia A. Pise-Masison;Maria Berg

  244
  Citations

• Tcf1 and Lef1 transcription factors establish CD8+ T cell identity through intrinsic HDAC activity

  Unknown

  235
  Citations

• TCF1 in T cell immunity: a broadened frontier

  Unknown

  221
  Citations

• The TCF-1 and LEF-1 Transcription Factors Have Cooperative and Opposing Roles in T Cell Development and Malignancy

  Shuyang Yu;Xinyuan Zhou;Farrah C. Steinke;Chengyu Liu

  215
  Citations

• Constitutive Activation of Wnt Signaling Favors Generation of Memory CD8 T Cells

  Dong-Mei Zhao;Shuyang Yu;Xinyuan Zhou;Jodie S. Haring

  203
  Citations

• IL-12 and type I interferon prolong the division of activated CD8 T cells by maintaining high-affinity IL-2 signaling in vivo

  Gabriel R. Starbeck-Miller;Hai-Hui Xue;John T. Harty

  203
  Citations

• TCF-1 and LEF-1 act upstream of Th-POK to promote the CD4 + T cell fate and interact with Runx3 to silence Cd4 in CD8 + T cells

  Farrah C. Steinke;Shuyang Yu;Xinyuan Zhou;Bing He

  199
  Citations

• The transcription factor c-Myb regulates CD8+ T cell stemness and antitumor immunity.

  Sanjivan Gautam;Jessica Fioravanti;Wei Zhu;John B Le Gall

  182
  Citations

• GA binding protein regulates interleukin 7 receptor alpha-chain gene expression in T cells.

  Hai-Hui Xue;Julie Bollenbacher;Valentina Rovella;Radhika Tripuraneni;Radhika Tripuraneni

  169
  Citations

• The transcription factor Runx3 guards cytotoxic CD8+ effector T cells against deviation towards follicular helper T cell lineage.

  Qiang Shan;Zhouhao Zeng;Shaojun Xing;Fengyin Li

  159
  Citations

• CD8+ T Lymphocyte Self-Renewal during Effector Cell Determination

  Wen-Hsuan W. Lin;Simone A. Nish;Bonnie Yen;Yen-Hua Chen

  152
  Citations

• CD4+ T cell effector commitment coupled to self-renewal by asymmetric cell divisions.

  Simone A. Nish;Kyra D. Zens;Radomir Kratchmarov;Wen-Hsuan W. Lin

  124
  Citations

• Cutting Edge: Generation of Memory Precursors and Functional Memory CD8+ T Cells Depends on T Cell Factor-1 and Lymphoid Enhancer-Binding Factor-1

  Unknown

  121
  Citations

• TCF1 and LEF1 Control Treg Competitive Survival and Tfr Development to Prevent Autoimmune Diseases

  Bi-Huei Yang;Ke Wang;Shuo Wan;Yan Liang

  121
  Citations

• The transcription factor TCF-1 enforces commitment to the innate lymphoid cell lineage.

  Christelle Harly;Devin Kenney;Gang Ren;Binbin Lai

  119
  Citations