What is he best known for?
The fields of study he is best known for:
- Gene
- Immune system
- Antibody
H R MacDonald focuses on Molecular biology, T lymphocyte, Antigen, Immunology and T cell.
His Molecular biology research is multidisciplinary, relying on both Endocrinology, Cytotoxic T cell, Interleukin 21, Lymphokine and Internal medicine.
H R MacDonald has researched Cytotoxic T cell in several fields, including Cellular differentiation, Stimulation and Immune system.
His Antigen research is multidisciplinary, relying on both T-Cell Receptor Beta Chain, Spleen, Serology and Pathology.
His Immunology study combines topics from a wide range of disciplines, such as Transplantation, Cytolysis and Glycoprotein.
His work carried out in the field of T cell brings together such families of science as Abnormal distribution, Nylon wool, Lymph, Cell biology and Distribution.
His most cited work include:
- Distinction of virgin and memory T lymphocytes. Stable acquisition of the Pgp-1 glycoprotein concomitant with antigenic stimulation. (436 citations)
- Activated B cells express receptors for, and proliferate in response to, pure interleukin 2. (317 citations)
- Developmentally regulated expression of T cell receptor beta chain variable domains in immature thymocytes. (204 citations)
What are the main themes of his work throughout his whole career to date?
H R MacDonald mainly investigates Molecular biology, T lymphocyte, Antigen, Cytolysis and T cell.
His Molecular biology study incorporates themes from Cellular differentiation, Lymphokine, Interleukin 2, Cytotoxic T cell and Monoclonal antibody.
His T lymphocyte study deals with the bigger picture of Immunology.
His studies in Antigen integrate themes in fields like Antibody and T-cell receptor.
His biological study spans a wide range of topics, including Precursor cell, CTL*, Lymphocyte subsets and Function.
H R MacDonald focuses mostly in the field of T cell, narrowing it down to matters related to Receptor and, in some cases, Endocrinology.
He most often published in these fields:
- Molecular biology (77.59%)
- T lymphocyte (53.45%)
- Antigen (41.38%)
What were the highlights of his more recent work (between 1987-1999)?
- Molecular biology (77.59%)
- CD8 (10.34%)
- Cytotoxic T cell (22.41%)
In recent papers he was focusing on the following fields of study:
H R MacDonald spends much of his time researching Molecular biology, CD8, Cytotoxic T cell, T cell and Epitope.
His Molecular biology research integrates issues from Beta, Immune tolerance, Antigen and T-cell receptor.
The study incorporates disciplines such as Congenic, Gene rearrangement and Transfection in addition to Antigen.
He has included themes like Ex vivo, CTL*, Lymphocyte and Virology in his T-cell receptor study.
His T cell study is associated with Immunology.
His Flow cytometry research incorporates elements of Spleen, T lymphocyte and Lymph.
Between 1987 and 1999, his most popular works were:
- Differential Requirement for CD4 Help in the Development of an Antigen-Specific CD8+ T Cell Response Depending on the Route of Immunization (30 citations)
- CD3-associated alpha/beta and gamma/delta heterodimeric receptors are expressed by distinct populations of CD4- CD8- thymocytes. (27 citations)
- FLOW-MICROFLUOROMETRIC MONITORING OF OLIGOCLONAL CD8+ T CELL RESPONSES TO AN IMMUNODOMINANT MOLONEY LEUKEMIA VIRUS-ENCODED EPITOPE IN VIVO (18 citations)
In his most recent research, the most cited papers focused on:
The scientist’s investigation covers issues in Molecular biology, CD8, Cytotoxic T cell, Epitope and T cell.
His Molecular biology research includes elements of CTL*, CD3, Immunization and T-cell receptor.
His CTL* study combines topics in areas such as Ex vivo, Lymphocyte and Virology.
The various areas that H R MacDonald examines in his CD3 study include Double negative, Receptor, Beta and Alpha.
His Immunization research is under the purview of Antigen.
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