D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 45 Citations 7,485 132 World Ranking 15750 National Ranking 6564

Research.com Recognitions

Awards & Achievements

1966 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

What is she best known for?

The fields of study she is best known for:

  • Enzyme
  • Biochemistry
  • Immune system

Her primary scientific interests are in Biochemistry, Depolarization, Chronic granulomatous disease, Superoxide and Membrane potential. Her Biochemistry study combines topics from a wide range of disciplines, such as Biophysics, Pathogen and Cryptococcus neoformans. Elizabeth R. Simons combines subjects such as Platelet, Thrombin and Phospholipase C with her study of Biophysics.

Her Depolarization research includes elements of Oxidase test, Granulocyte and Cytosol. In her research, Percoll, Centrifugation, Cell fractionation and Specific granule is intimately related to Cell biology, which falls under the overarching field of Superoxide. While the research belongs to areas of Membrane potential, she spends her time largely on the problem of Stimulation, intersecting her research to questions surrounding Cell membrane.

Her most cited work include:

  • Subcellular localization of the b-cytochrome component of the human neutrophil microbicidal oxidase: translocation during activation. (825 citations)
  • Chronic granulomatous disease: a syndrome of phagocyte oxidase deficiencies. (220 citations)
  • Cryptococcus neoformans Resides in an Acidic Phagolysosome of Human Macrophages (202 citations)

What are the main themes of her work throughout her whole career to date?

Elizabeth R. Simons mainly investigates Biochemistry, Platelet, Biophysics, Respiratory burst and Depolarization. Elizabeth R. Simons interconnects Stimulation and Calcium in the investigation of issues within Biochemistry. Elizabeth R. Simons has included themes like Secretion and Endocrinology in her Platelet study.

Her studies in Biophysics integrate themes in fields like Penicillamine and Intracellular pH. As a part of the same scientific family, Elizabeth R. Simons mostly works in the field of Respiratory burst, focusing on Degranulation and, on occasion, Cell biology. In Depolarization, Elizabeth R. Simons works on issues like Membrane potential, which are connected to Transmembrane protein.

She most often published in these fields:

  • Biochemistry (55.03%)
  • Platelet (40.27%)
  • Biophysics (30.20%)

What were the highlights of her more recent work (between 1995-2015)?

  • Biochemistry (55.03%)
  • Platelet activation (14.09%)
  • Platelet (40.27%)

In recent papers she was focusing on the following fields of study:

Elizabeth R. Simons mostly deals with Biochemistry, Platelet activation, Platelet, Respiratory burst and Amyloid precursor protein. Her research in Biochemistry intersects with topics in Azurophilic granule and Cryptococcus neoformans. The Platelet study combines topics in areas such as Endocrinology and Disease.

Her research on Respiratory burst also deals with topics like

  • Degranulation which is related to area like Secretion, Cytochalasin B, HEPES and Membrane potential,
  • Phagocytosis, which have a strong connection to Biophysics,
  • Chemotaxis and related Elastase and Stimulation,
  • Monocyte which is related to area like Mannose receptor. Her work deals with themes such as Amyloid beta, Thrombin, Metalloproteinase and Amyloid, which intersect with Amyloid precursor protein. Her biological study spans a wide range of topics, including Flow cytometry and Cell biology.

Between 1995 and 2015, her most popular works were:

  • Cryptococcus neoformans Resides in an Acidic Phagolysosome of Human Macrophages (202 citations)
  • Changes in neutrophil functions in astronauts. (117 citations)
  • Changes in monocyte functions of astronauts. (117 citations)

In her most recent research, the most cited papers focused on:

  • Enzyme
  • Biochemistry
  • Immune system

Elizabeth R. Simons focuses on Immunology, Respiratory burst, Biochemistry, Cell biology and Immune system. Many of her studies on Respiratory burst apply to Granule as well. Her Biochemistry research is multidisciplinary, relying on both Progenitor cell, Stem cell and Cryptococcus neoformans.

Elizabeth R. Simons has researched Cell biology in several fields, including Secretion, In vitro and Platelet. The Innate immune system and CD14 research Elizabeth R. Simons does as part of her general Immune system study is frequently linked to other disciplines of science, such as Spaceflight and Weightlessness, therefore creating a link between diverse domains of science. Her Signal transduction research integrates issues from Endocrinology, Alzheimer's disease, Amyloid precursor protein, Internal medicine and Platelet activation.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Subcellular localization of the b-cytochrome component of the human neutrophil microbicidal oxidase: translocation during activation.

N. Borregaard;J. M. Heiple;E. R. Simons;R. A. Clark.
Journal of Cell Biology (1983)

1059 Citations

Chronic granulomatous disease: a syndrome of phagocyte oxidase deficiencies.

Alfred I. Tauber;Niels Borregaard;Elizabeth Simons;Jonathan Wright.
Medicine (1983)

344 Citations

Non-age Related Differences in Thrombin Responses by Platelets from Male Patients with Advanced Alzheimer′s Disease

T.A. Davies;R.E. Fine;R.J. Johnson;C.A. Levesque.
Biochemical and Biophysical Research Communications (1993)

301 Citations

Activation of phospholipases A and C in human platelets exposed to epinephrine: role of glycoproteins IIb/IIIa and dual role of epinephrine.

Harjit Singh Banga;Elizabeth R. Simons;Lawrence F. Brass;Susan E. Rittenhouse.
Proceedings of the National Academy of Sciences of the United States of America (1986)

292 Citations

Cryptococcus neoformans Resides in an Acidic Phagolysosome of Human Macrophages

Stuart M. Levitz;Shu Hua Nong;Kurt F. Seetoo;Thomas S. Harrison.
Infection and Immunity (1999)

272 Citations

Correlation between membrane potential changes and superoxide production in human granulocytes stimulated by phorbol myristate acetate. Evidence for defective activation in chronic granulomatous disease.

J C Whitin;C E Chapman;E R Simons;M E Chovaniec.
Journal of Biological Chemistry (1980)

265 Citations

Changes in Cytoplasmic pH and in Membrane Potential in Thrombin-Stimulated Human Platelets

William C. Horne;Nancy E. Norman;David B. Schwartz;Elizabeth R. Simons.
FEBS Journal (1981)

202 Citations

Diminished calcium influx in lectin-stimulated T cells from old mice

Richard A. Miller;Bruce Jacobson;Gary Weil;Elizabeth R. Simons.
Journal of Cellular Physiology (1987)

187 Citations

Changes in neutrophil functions in astronauts.

Indreshpal Kaur;Elizabeth R Simons;Victoria A Castro;C Mark Ott.
Brain Behavior and Immunity (2004)

187 Citations

Changes in monocyte functions of astronauts.

Indreshpal Kaur;Elizabeth R. Simons;Victoria A. Castro;C. Mark Ott.
Brain Behavior and Immunity (2005)

185 Citations

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