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David P.D. Woldbye

David P.D. Woldbye

D-Index & Metrics

Neuroscience

D-Index
43
Citations
5910
World Ranking
7474
National Ranking
47

Overview

David P.D. Woldbye is affiliated with the University of Copenhagen in Denmark. Their research spans several interconnected fields, primarily focusing on biochemistry, genetics, molecular biology, and neuroscience, with significant overlaps in medicine. The core of their scientific contributions lies within cellular and molecular neuroscience, molecular biology, and genetics, with additional work touching on neurology and physiology.

The main topics covered in their research include neuroscience and neuropharmacology, genetics and neurodevelopmental disorders, virus-based gene therapy, RNA interference and gene delivery, epilepsy research and treatment, receptor mechanisms and signaling, and the influence of neurotransmitter receptors on behavior.

Among their recent scholarly publications are:

  • "Current and Future Prospects for Gene Therapy for Rare Genetic Diseases Affecting the Brain and Spinal Cord," 2021, Frontiers in Molecular Neuroscience
  • "Modeling the early stages of Alzheimer's disease by administering intracerebroventricular injections of human native Aβ oligomers to rats," 2022, Acta Neuropathologica Communications
  • "Gene Therapy Vector Encoding Neuropeptide Y and Its Receptor Y2 for Future Treatment of Epilepsy: Preclinical Data in Rats," 2020, Frontiers in Molecular Neuroscience
  • "Hypothalamic hormone-sensitive lipase regulates appetite and energy homeostasis," 2021, Molecular Metabolism
  • "Genome-wide association study of major anxiety disorders in 122,341 European-ancestry cases identifies 58 loci and highlights GABAergic signaling," 2024, bioRxiv (Cold Spring Harbor Laboratory)

Their work has appeared predominantly in the journals Frontiers in Molecular Neuroscience and bioRxiv, with multiple publications in each. Other venues for their research include Acta Neuropathologica Communications, the Journal of Biological Chemistry, and Molecular Metabolism.

Frequent collaborators in their research include Casper R. Gøtzsche, Mérab Kokaia, Søren H. Christiansen, Matthew D. Lycas, and Stanislava Pankratova, each contributing to multiple joint publications.

Best Publications

  • Powerful inhibition of kainic acid seizures by neuropeptide Y via Y5-like receptors.

    David P.D. Woldbye;Philip J. Larsen;Jens D. Mikkelsen;Kristian Klemp

  • A Subpopulation of Neuronal M4 Muscarinic Acetylcholine Receptors Plays a Critical Role in Modulating Dopamine-Dependent Behaviors

    Jongrye Jeon;Ditte Dencker;Gitta Wörtwein;David P.D. Woldbye

  • The role of NPY in learning and memory.

    C.R. Gøtzsche;D.P.D. Woldbye

  • Gene Therapy for Parkinson's Disease, An Update.

    Tobias M. Axelsen;David P.D. Woldbye

  • Role for M5 muscarinic acetylcholine receptors in cocaine addiction.

    Anders Fink-Jensen;Irina Fedorova;Gitta Wörtwein;David P. D. Woldbye

  • Neuropeptide Y inhibits hippocampal seizures and wet dog shakes

    David P.D. Woldbye;Torsten M. Madsen;Philip J. Larsen;Jens D. Mikkelsen;Jens D. Mikkelsen

  • In Vivo Characterization of High Basal Signaling from the Ghrelin Receptor

    Pia Steen Petersen;David P. D. Woldbye;Andreas Nygaard Madsen;Kristoffer L. Egerod

  • Differential roles for neuropeptide Y Y1 and Y5 receptors in anxiety and sedation.

    Gunnar Sørensen;Camilla Lindberg;Gitta Wörtwein;Tom G. Bolwig

  • Anxiolytic-Like Effects of Increased Ghrelin Receptor Signaling in the Amygdala

    Morten Jensen;Cecilia Ratner;Olga Rudenko;Søren H. Christiansen

  • Reduced Cocaine Self-Administration in Muscarinic M5 Acetylcholine Receptor-Deficient Mice

    Morgane Thomsen;David P. D. Woldbye;Gitta Wörtwein;Anders Fink-Jensen

  • Genome-wide association study of panic disorder reveals genetic overlap with neuroticism and depression.

    Andreas J. Forstner;Swapnil Awasthi;Christiane Wolf;Eduard Maron;Eduard Maron

  • Fluoxetine reverts chronic restraint stress-induced depression-like behaviour and increases neuropeptide Y and galanin expression in mice

    S.H. Christiansen;M.V. Olesen;G. Wörtwein;D.P.D. Woldbye

  • Neuropeptide Y promotes neurogenesis in murine subventricular zone.

    Fabienne Agasse;Liliana Bernardino;Heidi Kristiansen;Søren H. Christiansen

  • Electroconvulsive shocks increase the expression of neuropeptide Y (NPY) mRNA in the piriform cortex and the dentate gyrus.

    Jens D. Mikkelsen;David Woldbye;Jørn Kragh;Philip J. Larsen

  • Adeno-associated viral vector-induced overexpression of neuropeptide Y Y2 receptors in the hippocampus suppresses seizures.

    David P. D. Woldbye;Mikael Ängehagen;Casper R. Gøtzsche;Heidi Elbrønd-Bek

  • Prolonged induction of c-fos in neuropeptide Y- and somatostatin-immunoreactive neurons of the rat dentate gyrus after electroconvulsive stimulation

    David P.D. Woldbye;Mia H. Greisen;Tom G. Bolwig;Philip J. Larsen

  • Replication and meta-analysis of TMEM132D gene variants in panic disorder

    Angelika Erhardt;N Akula;J Schumacher;Darina Czamara

  • PICK1 Deficiency Impairs Secretory Vesicle Biogenesis and Leads to Growth Retardation and Decreased Glucose Tolerance

    Birgitte Holst;Kenneth L. Madsen;Anna M. Jansen;Chunyu Jin

  • Optogenetic control of human neurons in organotypic brain cultures

    My Andersson;Natalia Avaliani;Andreas Svensson;Jenny Wickham

  • Neuropeptide Y and its Involvement in Chronic Pain.

    Marta Diaz-delCastillo;David P.D. Woldbye;Anne Marie Heegaard

  • Differential suppression of seizures via Y2 and Y5 neuropeptide Y receptors

    David P D Woldbye;Avtandil Nanobashvili;Andreas Toft Sörensen;Henriette Husum

  • Increased cocaine self-administration in M4 muscarinic acetylcholine receptor knockout mice.

    Lene S. Schmidt;Morgane Thomsen;Pia Weikop;Ditte Dencker

Frequent Co-Authors

Gitta Wörtwein
Gitta Wörtwein University of Copenhagen
Merab Kokaia
Merab Kokaia Lund University
Anders D. Børglum
Anders D. Børglum Aarhus University
Lars H. Pinborg
Lars H. Pinborg Copenhagen University Hospital
Thomas Hansen
Thomas Hansen Copenhagen University Hospital
Merete Nordentoft
Merete Nordentoft University of Copenhagen
Gregers Wegener
Gregers Wegener Aarhus University
Elisabeth B. Binder
Elisabeth B. Binder Max Planck Society
Johannes Schumacher
Johannes Schumacher Philipp University of Marburg
Stephan Ripke
Stephan Ripke Massachusetts General Hospital

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