David M. Rothstein

Best Publications

• CD45 is a JAK phosphatase and negatively regulates cytokine receptor signalling

  Junko Irie-Sasaki;Junko Irie-Sasaki;Takehiko Sasaki;Takehiko Sasaki;Wataru Matsumoto;Anne Opavsky

  759
  Citations

• Regulatory B cells are identified by expression of TIM-1 and can be induced through TIM-1 ligation to promote tolerance in mice

  Qing Ding;Melissa Yeung;Geoffrey Camirand;Qiang Zeng

  522
  Citations

• T-cell costimulatory pathways in allograft rejection and tolerance.

  David M. Rothstein;Mohamed H. Sayegh

  307
  Citations

• Cyclic regulation of CD45 isoform expression in a long term human CD4+CD45RA+ T cell line.

  D M Rothstein;A Yamada;S F Schlossman;C Morimoto

  265
  Citations

• PDL1 Is Required for Peripheral Transplantation Tolerance and Protection from Chronic Allograft Rejection

  Katsunori Tanaka;Monica J. Albin;Xueli Yuan;Kazuhiro Yamaura

  228
  Citations

• Costimulatory pathways in transplantation: challenges and new developments.

  Xian Chang Li;David M. Rothstein;Mohamed H. Sayegh

  226
  Citations

• Non-self recognition by monocytes initiates allograft rejection

  Martin H. Oberbarnscheidt;Qiang Zeng;Qi Li;Hehua Dai

  221
  Citations

• The same epitope on CD22 of B lymphocytes mediates the adhesion of erythrocytes, T and B lymphocytes, neutrophils, and monocytes.

  P. Engel;Y. Nojima;D. Rothstein;Liang-Jl Zhou

  217
  Citations

• Ligation of VLA-4 on T cells stimulates tyrosine phosphorylation of a 105-kD protein.

  Y Nojima;D M Rothstein;K Sugita;S F Schlossman

  208
  Citations

• B-cell-specific checkpoint molecules that regulate anti-tumour immunity

  Unknown

  168
  Citations

• Immunologic Human Renal Allograft Injury Associates with an Altered IL-10/TNF-α Expression Ratio in Regulatory B Cells

  Aravind Cherukuri;David M. Rothstein;Brendan Clark;Clive R. Carter

  165
  Citations

• CTLA-4 up-regulation plays a role in tolerance mediated by CD45

  Scott Fecteau;Giacomo P. Basadonna;Alexander Freitas;Charlotte Ariyan

  158
  Citations

• Photoactive Porphyrin Derivative with Broad-Spectrum Activity against Oral Pathogens In Vitro

  Unknown

  153
  Citations

• Human antigen-specific memory T cells express the homing receptor (LAM-1) necessary for lymphocyte recirculation.

  Thomas F. Tedder;Takami Matsuyama;David Rothstein;Stuart F. Schlossman

  148
  Citations

• The emerging role of T cell Ig mucin 1 in alloimmune responses in an experimental mouse transplant model

  Takuya Ueno;Antje Habicht;Michael R. Clarkson;Monica J. Albin

  145
  Citations

• CTLA4 Expression Is an Indicator and Regulator of Steady-State CD4+FoxP3+ T Cell Homeostasis

  Anita L. Tang;John R. Teijaro;Modesta N. Njau;Smita S. Chandran

  144
  Citations

• Targeting Signal 1 Through CD45RB Synergizes with CD40 Ligand Blockade and Promotes Long Term Engraftment and Tolerance in Stringent Transplant Models

  David M. Rothstein;Mauren F. A. Livak;Koji Kishimoto;Charlotte Ariyan

  139
  Citations

• Differential regulation of activation-induced tyrosine phosphorylation and recruitment of SLP-76 to Vav by distinct isoforms of the CD45 protein-tyrosine phosphatase.

  Hideo Onodera;David G. Motto;Gary A. Koretzky;David M. Rothstein

  138
  Citations

• An Innate Response to Allogeneic Nonself Mediated by Monocytes

  Daniel Zecher;Nico van Rooijen;David M. Rothstein;Warren D. Shlomchik

  128
  Citations

• Small-Molecule Inhibition of PD-1 Transcription Is an Effective Alternative to Antibody Blockade in Cancer Therapy.

  Alison Taylor;Alison Taylor;David Rothstein;Christopher E Rudd

  128
  Citations