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Genetics

D-Index
61
Citations
12041
World Ranking
3075
National Ranking
1342

Overview

Colm O'hUigin is affiliated with Leidos in the United States and has contributed extensively to research in biochemistry, genetics, molecular biology, immunology, microbiology, and medicine. Their work spans significant subfields including molecular biology, immunology, epidemiology, virology, and genetics.

The scientist's research topics cover a range of areas such as gut microbiota and health, HIV research and treatment, immune response and inflammation, Mycobacterium research and diagnosis, vaccines and immunoinformatics approaches, antimicrobial peptides and activities, and cytomegalovirus and herpesvirus research.

Colm O'hUigin has published in various scientific venues. Frequent publication venues include:

  • The Journal of Immunology (3 publications)
  • Gut Pathogens (2 publications)
  • Immunogenetics (2 publications)
  • Proceedings of the National Academy of Sciences (1 publication)
  • Nature Communications (1 publication)

Recent papers authored or co-authored by O'hUigin include:

  • HLA tapasin independence: broader peptide repertoire and HIV control, 2020, Proceedings of the National Academy of Sciences
  • FAM3D is essential for colon homeostasis and host defense against inflammation associated carcinogenesis, 2020, Nature Communications
  • Population-specific diversity of the immunoglobulin constant heavy G chain (IGHG) genes, 2021, Genes and Immunity
  • Genome-wide Association Study Identifies HLA-DPB1 as a Significant Risk Factor for Severe Aplastic Anemia, 2020, The American Journal of Human Genetics
  • Distinct contributions of cathelin-related antimicrobial peptide (CRAMP) derived from epithelial cells and macrophages to colon mucosal homeostasis, 2020, The Journal of Pathology

Frequent co-authors collaborating with O'hUigin include:

  • Mary Carrington (5 publications)
  • Giorgio Trinchieri (5 publications)
  • Arman Bashirova (4 publications)
  • Keqiang Chen (4 publications)
  • Wanghua Gong (4 publications)

Best Publications

  • Genetic variation in IL28B and spontaneous clearance of hepatitis C virus

    David L. Thomas;Chloe L Thio;Maureen P. Martin;Ying Qi

  • MyD88-mediated signaling prevents development of adenocarcinomas of the colon: role of interleukin 18

    Rosalba Salcedo;Andrea Worschech;Marco Cardone;Yava Jones

  • The Molecular Descent of the Major Histocompatibility Complex

    Jan Klein;Yoko Satta;Colm O'Huigin;Naoyuki Takahata

  • MOLECULAR TRANS-SPECIES POLYMORPHISM

    Jan Klein;Akie Sato;Sandra Nagl;Colm O'hUigín

  • High HLA-DP Expression and Graft-versus-Host Disease.

    Effie W. Petersdorf;Mari Malkki;Colm O’hUigin;Mary Carrington

  • HLA-C cell surface expression and control of HIV/AIDS correlate with a variant upstream of HLA-C

    Rasmi Thomas;Richard Apps;Ying Qi;Xiaojiang Gao

  • The B30.2(SPRY) Domain of the Retroviral Restriction Factor TRIM5α Exhibits Lineage-Specific Length and Sequence Variation in Primates

    Byeongwoon Song;Bert Gold;Colm O'hUigin;Hassan Javanbakht

  • Phylogeny of Darwin's finches as revealed by mtDNA sequences.

    Akie Sato;Colm O’hUigin;Felipe Figueroa;Peter R. Grant

  • On the Origin of Darwin's Finches

    Akie Sato;Herbert Tichy;Colm O'hUigin;Peter R. Grant

  • Extensive MHC variability in cichlid fishes of Lake Malawi.

    Dagmar Klein;Hideki Ono;Hideki Ono;Colm O'hUigin;Vladimir Vincek

  • Identification and characterization of amelogenin genes in monotremes, reptiles, and amphibians.

    Satoru Toyosawa;Colm O’hUigin;Felipe Figueroa;Herbert Tichy

  • Intensity of natural selection at the major histocompatibility complex loci.

    Yoko Satta;Colm O'Huigin;Naoyuki Takahata;Jan Klein

  • Characterization of two novel Ly-6 genes. Protein sequence and potential structural similarity to alpha-bungarotoxin and other neurotoxins.

    T J Fleming;C O'hUigin;T R Malek

  • Effects of human TRIM5α polymorphisms on antiretroviral function and susceptibility to human immunodeficiency virus infection

    Hassan Javanbakht;Ping An;Bert Gold;Desiree C. Petersen

  • Major histocompatibility complex class II genes of zebrafish.

    Hideki Ono;Dagmar Klein;Vladimir Vincek;Felipe Figueroa

  • HLA-C expression levels define permissible mismatches in hematopoietic cell transplantation

    Effie W. Petersdorf;Effie W. Petersdorf;Theodore A. Gooley;Mari Malkki;Andrea P. Bacigalupo

  • Zebrafish Mhc class II alpha chain-encoding genes: polymorphism, expression, and function.

    Holger Sültmann;Werner E. Mayer;Felipe Figueroa;Colm O'hUigin

  • Organization of Mhc class II B genes in the zebrafish (Brachydanio rerio).

    Holger Sültmann;Werner E. Mayer;Figueroa Figueroa;Colm O’Huigin

  • How large was the founding population of Darwin's finches?

    Vladimir Vincek;Colm O'Huigin;Yoko Satta;Naoyuki Takahata

  • Convergent evolution of major histocompatibility complex molecules in humans and New World monkeys.

    Karin Kriener;Colm O'hUigin;Herbert Tichy;Jan Klein

Frequent Co-Authors

Jan Klein
Jan Klein Pennsylvania State University
Felipe Figueroa
Felipe Figueroa Max Planck Society
Mary Carrington
Mary Carrington Ragon Institute of MGH, MIT and Harvard
Yoko Satta
Yoko Satta The Graduate University for Advanced Studies, SOKENDAI
Xiaojiang Gao
Xiaojiang Gao National Institutes of Health
Holger Sültmann
Holger Sültmann German Cancer Research Center
Peter R. Grant
Peter R. Grant Princeton University
Joseph Sodroski
Joseph Sodroski Harvard Medical School
Masanori Kasahara
Masanori Kasahara Hokkaido University
Michael Dean
Michael Dean National Institutes of Health

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