World's Best Scientists 2026 revealed!

D-Index & Metrics

Microbiology

D-Index
72
Citations
17324
World Ranking
1762
National Ranking
750

Medicine

D-Index
72
Citations
17446
World Ranking
19863
National Ranking
9895

Overview

Clyde S. Crumpacker is primarily affiliated with Beth Israel Deaconess Medical Center in the United States. Their research spans multiple disciplines within biomedical science, focusing on immunology, microbiology, biochemistry, genetics, molecular biology, and medicine. The scientist's work emphasizes understanding immune responses, infectious diseases, and vaccine development, particularly in the context of viral infections such as HIV and SARS-CoV-2.

The main fields of study for Crumpacker include:

  • Immunology and Microbiology
  • Biochemistry, Genetics and Molecular Biology
  • Medicine

Their subfields of study focus on:

  • Molecular Biology
  • Virology
  • Infectious Diseases
  • Immunology

Prominent topics covered in their research include:

  • HIV Research and Treatment
  • SARS-CoV-2 and COVID-19 Research
  • Vaccines and Immunoinformatics Approaches
  • Immune Responses and Vaccinations
  • Epigenetics and DNA Methylation
  • RNA Modifications and Cancer

Crumpacker has contributed to recent scientific literature with a series of papers primarily authored by Jielin Zhang, indicating frequent collaboration. The recent publications are:

  • "HIV UTR, LTR, and Epigenetic Immunity," 2022, Viruses
  • "Systems Vaccinology in HIV Vaccine Development," 2022, Vaccines
  • "Approaches to pandemic prevention - the chromatin vaccine," 2023, Frontiers in Immunology
  • "A Leap Forward in Vaccinology by cVacc Elicited Epigenetic Immunity," 2025, Preprints.org

Frequent collaborators with Crumpacker include:

  • Jielin Zhang
  • Philip W. Askenase
  • Rudolf Jaenisch

The scientist's work appears regularly in specialized venues such as:

  • Viruses
  • Vaccines
  • Frontiers in Immunology
  • Preprints.org

Crumpacker's research involves exploring vaccine development through systems vaccinology, epigenetic immunity related to HIV, and strategies for pandemic prevention. Their multidisciplinary approach integrates molecular biology techniques with immunological insights to address infectious disease challenges.

Best Publications

  • Infective Endocarditis: An Analysis Based on Strict Case Definitions

    C. Fordham Von Reyn;Barry S. Levy;Robert D. Arbeit;Gerald Friedland

  • Guidelines for preventing opportunistic infections among HIV-infected persons - 2002

    Henry Masur;Jonathan E. Kaplan;King K. Holmes;Beverly Alston

  • Rapid and durable antiretroviral effect of the HIV-1 Integrase inhibitor raltegravir as part of combination therapy in treatment-naive patients with HIV-1 infection: results of a 48-week controlled study.

    Martin Markowitz;Bach-Yen Nguyen;Eduardo Gotuzzo;Fernando Mendo

  • Acyclovir-resistant herpes simplex virus infections in patients with the acquired immunodeficiency syndrome.

    Kim S. Erlich;John Mills;Pamela Chatis;Gregory J. Mertz

  • A Controlled Trial Comparing Continued Zidovudine with Didanosine in Human Immunodeficiency Virus Infection

    Kahn Jo;Lagakos Sw;Richman Dd;Cross A

  • Resistance to Antiviral Drugs of Herpes Simplex Virus Isolated from a Patient Treated with Acyclovir

    Clyde S. Crumpacker;Lowell E. Schnipper;Steven I. Marlowe;Patricia N. Kowalsky

  • A Controlled Trial Comparing Foscarnet with Vidarabine for Acyclovir-Resistant Mucocutaneous Herpes Simplex in the Acquired Immunodeficiency Syndrome

    Sharon Safrin;Clyde Crumpacker;Pam Chatis;Roger Davis

  • Growth Inhibition by Acycloguanosine of Herpesviruses Isolated from Human Infections

    Clyde S. Crumpacker;Lowell E. Schnipper;John A. Zaia;Myron J. Levin

  • Oral ganciclovir as maintenance treatment for cytomegalovirus retinitis in patients with AIDS. Syntex Cooperative Oral Ganciclovir Study Group.

    W L Drew;D Ives;J P Lalezari;C Crumpacker

  • Ribavirin antagonizes the effect of azidothymidine on HIV replication

    Markus W. Vogt;Kevan L. Hartshorn;Phillip A. Furman;Ting-Chao Chou

  • Zidovudine resistance and HIV-1 disease progression during antiretroviral therapy

    Richard T. D'Aquila;Victoria A. Johnson;Seth L. Welles;Anthony J. Japour

  • Resistance of herpes simplex virus to acycloguanosine: role of viral thymidine kinase and DNA polymerase loci

    Lowell E. Schnipper;Clyde S. Crumpacker

  • Three inhibitors of type 1 human immunodeficiency virus long terminal repeat-directed gene expression and virus replication.

    Chiang J. Li;Lin J. Zhang;Bruce J. Dezube;Clyde S. Crumpacker

  • Nonresponsiveness to Hepatitis B Vaccine in Health Care Workers: Results of Revaccination and Genetic Typings

    D E Craven;Z L Awdeh;L M Kunches;E J Yunis

  • Successful Treatment with Foscarnet of an Acyclovir-Resistant Mucocutaneous Infection with Herpes Simplex Virus in a Patient with Acquired Immunodeficiency Syndrome

    P.A. Chatis;C.H. Miller;L.E. Schrager;C.S. Crumpacker

  • Hepatitis B Vaccine in Health Care Personnel: Safety, lmmunogenicity, and Indicators of Efficacy

    Jules L. Dienstag;Barbara G. Werner;B. Frank Polk;David R. Snydman

  • Mechanism of action of foscarnet against viral polymerases.

    Clyde S. Crumpacker

  • Progressive polyradiculopathy in acquired immune deficiency syndrome

    David Eidelberg;Ana Sotrel;Hannes Vogel;Paul Walker

  • Association of Plasma Human Immunodeficiency Virus Type 1 RNA Level with Risk of Clinical Progression in Patients with Advanced Infection

    R. W. Coombs;S. L. Welles;C. Hooper;P. S. Reichelderfer

  • Cytomegalovirus Infection Causes an Increase of Arterial Blood Pressure

    Jilin Cheng;Qingen Ke;Zhuang Jin;Haibin Wang

  • Recurrence and Resistance Patterns of Herpes Simplex Virus following Cessation of ⩾6 Years of Chronic Suppression with Acyclovir

    Kenneth H. Fife;Clyde S. Crumpacker;Gregory J. Mertz;Edgar L. Hill

Frequent Co-Authors

Myron J. Levin
Myron J. Levin University of Colorado Anschutz Medical Campus
David R. Snydman
David R. Snydman Tufts Medical Center
Bruce J. Dezube
Bruce J. Dezube Beth Israel Deaconess Medical Center
Stephen A. Spector
Stephen A. Spector University of California, San Diego
Akira Matsumori
Akira Matsumori International Society of Cardiomyopathy , Myocarditis, and Heart Failure
Richard Platt
Richard Platt Harvard University
Donald E. Craven
Donald E. Craven Tufts University
Jules L. Dienstag
Jules L. Dienstag Harvard University
Arthur B. Pardee
Arthur B. Pardee Harvard University
Adriana Weinberg
Adriana Weinberg University of Colorado Anschutz Medical Campus

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