World's Best Scientists 2026 revealed!
C. Michael Knudson

C. Michael Knudson

D-Index & Metrics

Biology and Biochemistry

D-Index
46
Citations
15394
World Ranking
18825
National Ranking
7688

Overview

C. Michael Knudson is affiliated with the University of Iowa in the United States and has contributed extensively to the field of medicine, focusing primarily on infectious diseases, hematology, neurology, biochemistry, and genetics. Their research spans several interrelated disciplines, with a significant emphasis on COVID-19 clinical research and blood transfusion science.

The scientist's work can be categorized under the following main fields of study:

  • Medicine

Within this broad field, their known subfields of study include:

  • Infectious Diseases
  • Hematology
  • Neurology
  • Biochemistry
  • Genetics

Their primary research topics reflect a focus on:

  • COVID-19 Clinical Research Studies
  • Blood groups and transfusion
  • SARS-CoV-2 and COVID-19 Research
  • Blood transfusion and management
  • Hemoglobinopathies and Related Disorders
  • Olfactory and Sensory Function Studies
  • Neuroinflammation and Neurodegeneration Mechanisms

C. Michael Knudson is frequently published in journals such as:

  • Transfusion
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Transfusion and Apheresis Science
  • Nature
  • Journal of Clinical Laboratory Analysis

Collaborations are a significant aspect of their research, with frequent co-authors including:

  • Judith Leon
  • J. Brooks Jackson
  • Anna E. Merrill
  • Kai J. Rogers
  • Spencer Dempewolf

Among their recent publications are the following papers, which illustrate the range and topics of their research contributions:

  • "COVID-19 treatments and pathogenesis including anosmia in K18-hACE2 mice" (2020, Nature)
  • "ABO-incompatible platelets are associated with increased transfusion reaction rates" (2020, Transfusion)
  • "COVID-19 convalescent plasma: phase 2" (2020, Transfusion)
  • "Exponential increase in neutralizing and spike specific antibodies following vaccination of COVID-19 convalescent plasma donors" (2021, Transfusion)
  • "K18-hACE2 Mice for Studies of COVID-19 Treatments and Pathogenesis Including Anosmia" (2020, bioRxiv [Cold Spring Harbor Laboratory])

Best Publications

  • Bax-deficient mice with lymphoid hyperplasia and male germ cell death

    C. Michael Knudson;Kenneth S. K. Tung;Warren G. Tourtellotte;Gary A. J. Brown

  • BAX is required for neuronal death after trophic factor deprivation and during development

    Thomas L. Deckwerth;Jeffrey L. Elliott;C. Michael Knudson;Eugene M. Johnson

  • Bax suppresses tumorigenesis and stimulates apoptosis in vivo

    C Yin;C M Knudson;S J Korsmeyer;T Van Dyke

  • Bax Deletion Further Orders the Cell Death Pathway in Cerebellar Granule Cells and Suggests a Caspase-independent Pathway to Cell Death

    Timothy M. Miller;Krista L. Moulder;C. Michael Knudson;Douglas J. Creedon

  • Bcl-2 and Bax function independently to regulate cell death.

    C M Knudson;S J Korsmeyer

  • bax-deficiency promotes drug resistance and oncogenic transformation by attenuating p53-dependent apoptosis

    Mila E. McCurrach;Thomas M. F. Connor;C. Michael Knudson;Stanley J. Korsmeyer

  • Widespread elimination of naturally occurring neuronal death in Bax-deficient mice.

    Fletcher A. White;Cynthia R. Keller-Peck;C. Michael Knudson;Stanley J. Korsmeyer

  • COVID-19 treatments and pathogenesis including anosmia in K18-hACE2 mice.

    Jian Zheng;Lok-Yin Roy Wong;Kun Li;Abhishek Kumar Verma

  • The brain ryanodine receptor: a caffeine-sensitive calcium release channel

    Peter S. McPhersonx;Young Kee Kim;Hector Valdivia;C. Michael Knudson

  • Bax Involvement in p53-Mediated Neuronal Cell Death

    Hong Xiang;Yoshito Kinoshita;C. Michael Knudson;Stanley J. Korsmeyer

  • HYPERGLYCEMIA INDUCES APOPTOSIS IN PRE-IMPLANTATION EMBRYOS THROUGH CELL DEATH EFFECTOR PATHWAYS

    K.H. Moley;M.M.-Y. Chi;C.M. Knudson;S.J. Korsmeyer

  • Complete dissociation of motor neuron death from motor dysfunction by Bax deletion in a mouse model of ALS.

    Thomas W. Gould;Robert R. Buss;Sharon Vinsant;David Prevette

  • Prolongation of ovarian lifespan into advanced chronological age by Bax -deficiency

    Gloria I. Perez;Rodolfo Robles;C. Michael Knudson;Jodi A. Flaws;Jodi A. Flaws

  • APOPTOSIS-ASSOCIATED SIGNALING PATHWAYS ARE REQUIRED FOR CHEMOTHERAPY-MEDIATED FEMALE GERM CELL DESTRUCTION

    Perez Gi;Knudson Cm;Leykin L;Korsmeyer Sj

  • Subcellular fractionation of dystrophin to the triads of skeletal muscle

    E P Hoffman;C M Knudson;K P Campbell;L M Kunkel;L M Kunkel

  • A lethal mutation in mice eliminates the slow calcium current in skeletal muscle cells.

    Beam Kg;Knudson Cm;Powell Ja

  • Identification and characterization of the high affinity [3H]ryanodine receptor of the junctional sarcoplasmic reticulum Ca2+ release channel.

    K P Campbell;C M Knudson;T Imagawa;A T Leung

  • Bax-Dependent Spermatogonia Apoptosis Is Required for Testicular Development and Spermatogenesis

    Lonnie D. Russell;Helio Chiarini-Garcia;Stanley J. Korsmeyer;C. Michael Knudson

  • Ryanodine receptor of skeletal muscle is a gap junction-type channel

    Jianjie Ma;M. Fill;C. M. Knudson;K. P. Campbell

  • Bcl-xL/Bcl-2 coordinately regulates apoptosis, cell cycle arrest and cell cycle entry

    Yelena M. Janumyan;Courtney G. Sansam;Anuja Chattopadhyay;Ningli Cheng

Frequent Co-Authors

Stanley J. Korsmeyer
Stanley J. Korsmeyer Harvard University
Douglas R. Spitz
Douglas R. Spitz University of Iowa
David K. Meyerholz
David K. Meyerholz University of Iowa
Charles G. Mullighan
Charles G. Mullighan St. Jude Children's Research Hospital
Kevin P. Campbell
Kevin P. Campbell University of Iowa
J. Brooks Jackson
J. Brooks Jackson University of Iowa Hospitals and Clinics
Stanley Perlman
Stanley Perlman University of Iowa
William D. Snider
William D. Snider University of North Carolina at Chapel Hill
Todd E. Scheetz
Todd E. Scheetz University of Iowa
Jeffrey C. Murray
Jeffrey C. Murray University of Iowa

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