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D-Index
99
Citations
41489
World Ranking
8511
National Ranking
336

Overview

Bruce H. R. Wolffenbuttel is affiliated with the University Medical Center Groningen in the Netherlands. Their research primarily spans the fields of medicine and biochemistry, genetics, and molecular biology, with significant contributions in endocrinology, diabetes and metabolism, genetics, molecular biology, clinical biochemistry, and surgery.

The scientist's main topics of research focus on diabetes management and research, diabetes and associated disorders, genetic associations and epidemiology, diabetes treatment and management, advanced glycation end products research, diabetes, cardiovascular risks, and lipoproteins, as well as the effects and risks of endocrine disrupting chemicals.

Recent notable publications include:

  • Genomic analysis of diet composition finds novel loci and associations with health and lifestyle (2020), published in Molecular Psychiatry
  • Genetic analysis in European ancestry individuals identifies 517 loci associated with liver enzymes (2021), published in Nature Communications
  • The importance of vitamin B12 for individuals choosing plant-based diets (2022), published in European Journal of Nutrition
  • Relationship between serum B12 concentrations and mortality: experience in NHANES (2020), published in BMC Medicine
  • Identification, Heritability, and Relation With Gene Expression of Novel DNA Methylation Loci for Blood Pressure (2020), published in Hypertension

Bruce H. R. Wolffenbuttel frequently collaborates with a range of co-authors, including:

  • Melanie M. van der Klauw
  • Henk-Jan Aanstoot
  • Pytrik Folkertsma
  • Sipko van Dam
  • José Castela Forte

Publication venues where Wolffenbuttel has contributed multiple times include:

  • Scientific Reports
  • BMJ Open Diabetes Research & Care
  • Research Square (Research Square)
  • SSRN Electronic Journal
  • Environmental Research

Best Publications

  • Discovery and refinement of loci associated with lipid levels

    Cristen J. Willer;Ellen M. Schmidt;Sebanti Sengupta;Gina M. Peloso;Gina M. Peloso;Gina M. Peloso

  • Effects of ramipril on cardiovascular and microvascular outcomes in people with diabetes mellitus: results of the HOPE study and MICRO-HOPE substudy

    Hope Hope Study Investigators;B.H.R. Wolffenbuttel

  • Common variants associated with plasma triglycerides and risk for coronary artery disease

    Ron Do;Cristen J. Willer;Ellen M. Schmidt;Sebanti Sengupta

  • Genome-wide association analyses identify 18 new loci associated with serum urate concentrations

    Anna Köttgen;Anna Köttgen;Eva Albrecht;Alexander Teumer;Veronique Vitart

  • Cohort Profile: LifeLines, a three-generation cohort study and biobank

    Salome Scholtens;Nynke Smidt;Morris A. Swertz;Stephan J. L. Bakker

  • Health-related quality of life and treatment satisfaction in Dutch patients with type 2 diabetes

    W. Ken Redekop;Marc A. Koopmanschap;Ronald P. Stolk;Guy E.H.M. Rutten

  • Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture

    Sonja I Berndt;Stefan Gustafsson;Stefan Gustafsson;Reedik Mägi;Reedik Mägi;Andrea Ganna

  • Thyroid Function Is Associated with Components of the Metabolic Syndrome in Euthyroid Subjects

    Annemieke Roos;Stephan J. L. Bakker;Thera P. Links;Rijk O. B. Gans

  • Ramipril and the development of diabetes.

    Salim Yusuf;Hertzel Gerstein;Byron Hoogwerf;Janice Pogue

  • The prevalence of metabolic syndrome and metabolically healthy obesity in Europe: a collaborative analysis of ten large cohort studies.

    Jana V van Vliet-Ostaptchouk;Marja-Liisa Nuotio;Marja-Liisa Nuotio;Sandra N Slagter;Dany Doiron

  • Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche

    John R.B. Perry;Felix Day;Cathy E. Elks;Patrick Sulem

  • Genomic analyses identify hundreds of variants associated with age at menarche and support a role for puberty timing in cancer risk

    Felix R. Day;Deborah J. Thompson;Hannes Helgason;Hannes Helgason;Daniel I. Chasman

  • Breakers of advanced glycation end products restore large artery properties in experimental diabetes

    Bruce H. R. Wolffenbuttel;Chantal M. Boulanger;Francy R. L. Crijns;Maya S. P. Huijberts

  • Universal risk factors for multifactorial diseases: LifeLines: a three-generation population-based study.

    Ronald P. Stolk;Judith G. M. Rosmalen;Dirkje S. Postma;Rudolf A. de Boer

  • Large-scale genomic analyses link reproductive aging to hypothalamic signaling, breast cancer susceptibility and BRCA1-mediated DNA repair

    Felix R. Day;Katherine S. Ruth;Deborah J Thompson;Kathryn L. Lunetta

  • Impact of common genetic determinants of Hemoglobin A1c on type 2 diabetes risk and diagnosis in ancestrally diverse populations: A transethnic genome-wide meta-analysis

    Eleanor Wheeler;Aaron Leong;Ching-Ti Liu;Marie-France Hivert

  • Meta-analyses identify 13 loci associated with age at menopause and highlight DNA repair and immune pathways

    Lisette Stolk;John R B Perry;John R B Perry;Daniel I. Chasman;Chunyan He

  • Characterization of the human visceral adipose tissue secretome

    Gloria Alvarez-Llamas;Ewa Szalowska;Marcel P. de Vries;Desiree Weening

  • Genomic analyses identify hundreds of variants associated with age at menarche and support a role for puberty timing in cancer risk

    Day Fr;Thompson Dj;elgason H;Chasman Di

  • Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture

    Sonja I. Berndt;Stefan Gustafsson;Reedik Maegi;Andrea Ganna

Frequent Co-Authors

Harold Snieder
Harold Snieder University Medical Center Groningen
Jana V. van Vliet-Ostaptchouk
Jana V. van Vliet-Ostaptchouk University of Groningen
Ronald P. Stolk
Ronald P. Stolk University Medical Center Groningen
Tonu Esko
Tonu Esko University of Tartu
Christian Gieger
Christian Gieger Helmholtz Zentrum München
Andres Metspalu
Andres Metspalu University of Tartu
Pim van der Harst
Pim van der Harst University Medical Center Utrecht
Tim D. Spector
Tim D. Spector King's College London
André G. Uitterlinden
André G. Uitterlinden Erasmus University Rotterdam
Bruce M. Psaty
Bruce M. Psaty University of Washington

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