Timothy P. Dalton

Overview

Best Publications

• REGULATION OF GENE EXPRESSION BY REACTIVE OXYGEN

  Timothy P. Dalton;Howard G. Shertzer;Alvaro Puga

  1602
  Citations

• Role of Aryl Hydrocarbon Receptor-mediated Induction of the CYP1 Enzymes in Environmental Toxicity and Cancer

  Daniel W. Nebert;Timothy P. Dalton;Allan B. Okey;Frank J. Gonzalez

  1355
  Citations

• Role of the aromatic hydrocarbon receptor and [Ah] gene battery in the oxidative stress response, cell cycle control, and apoptosis

  Daniel W Nebert;Amy L Roe;Matthew Z Dieter;Willy A Solis

  1190
  Citations

• The role of cytochrome P450 enzymes in endogenous signalling pathways and environmental carcinogenesis.

  Daniel W. Nebert;Timothy P. Dalton

  1059
  Citations

• Aromatic hydrocarbon receptor interaction with the retinoblastoma protein potentiates repression of E2F-dependent transcription and cell cycle arrest

  Alvaro Puga;Sonya J. Barnes;Timothy P. Dalton;Ching Yi Chang

  415
  Citations

• Determining glutathione and glutathione disulfide using the fluorescence probe o-phthalaldehyde.

  Albert P. Senft;Timothy P. Dalton;Howard G. Shertzer

  406
  Citations

• ZIP8, member of the solute-carrier-39 (SLC39) metal-transporter family: characterization of transporter properties

  Lei He;Kuppuswami Girijashanker;Timothy P Dalton;Jodie Reed

  380
  Citations

• Slc39a14 Gene Encodes ZIP14, A Metal/Bicarbonate Symporter: Similarities to the ZIP8 Transporter

  Kuppuswami Girijashanker;Lei He;Manoocher Soleimani;Jodie M. Reed

  373
  Citations

• Oral exposure to benzo[a]pyrene in the mouse: detoxication by inducible cytochrome P450 is more important than metabolic activation.

  Shigeyuki Uno;Timothy P. Dalton;Sandrine Derkenne;Christine P. Curran

  372
  Citations

• Oxidative and electrophilic stress induces multidrug resistance–associated protein transporters via the nuclear factor‐E2–related factor‐2 transcriptional pathway

  Jonathan M. Maher;Matthew Z. Dieter;Lauren M. Aleksunes;Angela L. Slitt;Angela L. Slitt

  369
  Citations

• Genetically altered mice to evaluate glutathione homeostasis in health and disease.

  Timothy P. Dalton;Ying Chen;Scott N. Schneider;Daniel W. Nebert

  358
  Citations

• Novel n-3 Fatty Acid Oxidation Products Activate Nrf2 by Destabilizing the Association between Keap1 and Cullin3 *

  Ling Gao;Jiakun Wang;Konjeti R. Sekhar;Huiyong Yin

  344
  Citations

• Initial characterization of the glutamate-cysteine ligase modifier subunit Gclm(-/-) knockout mouse: novel model system for a severely compromised oxidative stress response

  Yi Yang;Matthew Z. Dieter;Ying Chen;Howard G. Shertzer

  342
  Citations

• Oral benzo[a]pyrene in Cyp1 knockout mouse lines: CYP1A1 important in detoxication, CYP1B1 metabolism required for immune damage independent of total-body burden and clearance rate.

  Shigeyuki Uno;Timothy P. Dalton;Nadine Dragin;Christine P. Curran

  313
  Citations

• Oxidative Stress Activates Metal-responsive Transcription Factor-1 Binding Activity OCCUPANCY IN VIVO OF METAL RESPONSE ELEMENTS IN THE METALLOTHIONEIN-I GENE PROMOTER

  Tim P. Dalton;Qingwen Li;Doug Bittel;Luchuan Liang

  302
  Citations

• Knockout of the mouse glutamate cysteine ligase catalytic subunit (Gclc) gene: embryonic lethal when homozygous, and proposed model for moderate glutathione deficiency when heterozygous.

  Timothy P. Dalton;Matthew Z. Dieter;Yi Yang;Howard G. Shertzer

  298
  Citations

• Glutamate cysteine ligase catalysis: dependence on ATP and modifier subunit for regulation of tissue glutathione levels.

  Ying Chen;Howard G. Shertzer;Scott N. Schneider;Daniel W. Nebert

  294
  Citations

• Redox Dysregulation Affects the Ventral But Not Dorsal Hippocampus: Impairment of Parvalbumin Neurons, Gamma Oscillations, and Related Behaviors

  Pascal Steullet;Jan-Harry Cabungcal;Anita Kulak;Rudolf Kraftsik

  283
  Citations

• Induction of cellular oxidative stress by aryl hydrocarbon receptor activation.

  Timothy P Dalton;Alvaro Puga;Howard G Shertzer

  246
  Citations

• Dioxin causes a sustained oxidative stress response in the mouse.

  Howard G. Shertzer;Daniel W. Nebert;Alvaro Puga;Michelle Ary

  224
  Citations