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Theo de Witte is affiliated with Radboud University in the Netherlands, focusing primarily on medical research within the field of hematology. Their research contributions span across several hematological diseases and related clinical outcomes, with a significant focus on acute myeloid leukemia (AML) and myelodysplastic syndromes (MDS).

Their recent publications include:

  • Midostaurin reduces relapse in FLT3-mutant acute myeloid leukemia: the Alliance CALGB 10603/RATIFY trial, 2021, Leukemia
  • Novel dynamic outcome indicators and clinical endpoints in myelodysplastic syndrome; the European LeukemiaNet MDS Registry and MDS-RIGHT project perspective, 2020, Haematologica
  • Toxic iron species in lower-risk myelodysplastic syndrome patients: course of disease and effects on outcome, 2020, Leukemia
  • A predictive algorithm using clinical and laboratory parameters may assist in ruling out and in diagnosing MDS, 2021, Blood Advances
  • Benign ethnic neutropenia: an analysis of prevalence, timing and identification accuracy in two large inner-city NHS hospitals, 2021, BMC Psychiatry

Theo de Witte's work covers a range of topics within hematology and related diseases. Main research topics include:

  • Acute Myeloid Leukemia Research
  • Acute Lymphoblastic Leukemia research
  • Hematopoietic Stem Cell Transplantation
  • Myeloproliferative Neoplasms: Diagnosis and Treatment
  • Hematological disorders and diagnostics
  • Neutropenia and Cancer Infections
  • Chronic Myeloid Leukemia Treatments

Their main fields of study and subfields consist of medicine with a strong emphasis on hematology. Additional subfields include public health, environmental and occupational health, genetics, oncology, and emergency medicine.

Theo de Witte frequently publishes in venues such as:

  • Blood Advances
  • British Journal of Haematology
  • HemaSphere
  • Leukemia
  • Haematologica

Collaboration is a significant part of their work, with frequent coauthors being:

  • Reinhard Stauder
  • Pierre Fenaux
  • Argiris Symeonidis
  • Corine van Marrewijk
  • Saskia Langemeijer

Best Publications

  • Midostaurin plus Chemotherapy for Acute Myeloid Leukemia with a FLT3 Mutation

    Richard M. Stone;Sumithra J. Mandrekar;Ben L. Sanford;Kristina Laumann

  • Clinical application and proposal for modification of the International Working Group (IWG) response criteria in myelodysplasia

    Bruce D. Cheson;Peter L. Greenberg;John M. Bennett;Bob Lowenberg

  • Somatic mutations of the histone methyltransferase gene EZH2 in myelodysplastic syndromes

    Gorica Nikoloski;Saskia M C Langemeijer;Roland P Kuiper;Ruth Knops

  • Acquired mutations in TET2 are common in myelodysplastic syndromes

    Saskia M C Langemeijer;Roland P Kuiper;Marieke Berends;Ruth Knops

  • Diagnosis and treatment of primary myelodysplastic syndromes in adults: recommendations from the European LeukemiaNet

    Luca Malcovati;Eva Hellström-Lindberg;David Bowen;Lionel Adès

  • Low-Dose Decitabine Versus Best Supportive Care in Elderly Patients With Intermediate- or High-Risk Myelodysplastic Syndrome (MDS) Ineligible for Intensive Chemotherapy: Final Results of the Randomized Phase III Study of the European Organisation for Research and Treatment of Cancer Leukemia Group and the German MDS Study Group

    Michael Lübbert;Stefan Suciu;Liliana Baila;Björn Hans Rüter

  • Allogeneic compared with autologous stem cell transplantation in the treatment of patients younger than 46 years with acute myeloid leukemia (AML) in first complete remission (CR1): an intention-to-treat analysis of the EORTC/GIMEMAAML-10 trial

    Stefan Suciu;Franco Mandelli;Theo de Witte;Robert Zittoun

  • Allogeneic stem cell transplantation after reduced-intensity conditioning in patients with myelofibrosis: a prospective, multicenter study of the Chronic Leukemia Working Party of the European Group for Blood and Marrow Transplantation

    Nicolaus Kröger;Ernst Holler;Guido Kobbe;Martin Bornhäuser

  • Retrospective comparison of reduced-intensity conditioning and conventional high-dose conditioning for allogeneic hematopoietic stem cell transplantation using HLA-identical sibling donors in myelodysplastic syndromes.

    Rodrigo Martino;Simona Iacobelli;Ronald Brand;Thekla Jansen

  • Risk score for outcome after allogeneic hematopoietic stem cell transplantation: a retrospective analysis.

    Alois Gratwohl;Martin Stern;Ronald Brand;Jane Apperley

  • Gemtuzumab Ozogamicin Versus Best Supportive Care in Older Patients With Newly Diagnosed Acute Myeloid Leukemia Unsuitable for Intensive Chemotherapy: Results of the Randomized Phase III EORTC-GIMEMA AML-19 Trial

    Sergio Amadori;Stefan Suciu;Dominik Selleslag;Franco Aversa

  • Hematopoietic malignancies demonstrate loss-of-function mutations of BAX.

    Jules P.P. Meijerink;Ewald J.B.M. Mensink;Kun Wang;Thomas W. Sedlak

  • Allogeneic hematopoietic stem cell transplantation for MDS and CMML: recommendations from an international expert panel

    Theo De Witte;David Bowen;Marie Robin;Luca Malcovati

  • Allogeneic Hematopoietic Stem-Cell Transplantation for Patients 50 Years or Older With Myelodysplastic Syndromes or Secondary Acute Myeloid Leukemia

    ZiYi Lim;Ronald Brand;Rodrigo Martino;Anja van Biezen

  • Induction of myelodysplasia by myeloid-derived suppressor cells.

    Xianghong Chen;Erika A. Eksioglu;Junmin Zhou;Ling Zhang

  • Haematopoietic stem cell transplantation for patients with myelo- dysplastic syndromes and secondary acute myeloid leukaemias: a report on behalf of the Chronic Leukaemia Working Party of the European Group for Blood and Marrow Transplantation (EBMT)

    Theo De Witte;Jo Hermans;Jaak Vossen;Andrea Bacigalupo

  • Bone marrow transplantation from HLA-identical siblings as treatment for myelodysplasia.

    Jorge Sierra;Waleska S. Pérez;Ciril Rozman;Enric Carreras

  • Clinical-grade generation of active NK cells from cord blood hematopoietic progenitor cells for immunotherapy using a closed-system culture process.

    Jan Spanholtz;Frank Preijers;Marleen Tordoir;Carel Trilsbeek

  • Standardization of flow cytometry in myelodysplastic syndromes: report from the first European LeukemiaNet working conference on flow cytometry in myelodysplastic syndromes

    Arjan A. van de Loosdrecht;Canan Alhan;Marie Christine Béné;Matteo G. Della Porta

  • Standardization of flow cytometry in myelodysplastic syndromes: a report from an international consortium and the European LeukemiaNet Working Group.

    T. M. Westers;Robin M Ireland;W. Kern;C. Alhan

Frequent Co-Authors

Dietger Niederwieser
Dietger Niederwieser Leipzig University
Joop H. Jansen
Joop H. Jansen Radboud University
Nicolaus Kröger
Nicolaus Kröger Universität Hamburg
Stefan Suciu
Stefan Suciu European Organisation for Research and Treatment of Cancer
Ulrich Germing
Ulrich Germing Heinrich Heine University Düsseldorf
Sergio Amadori
Sergio Amadori University of Rome Tor Vergata
Eva Hellström-Lindberg
Eva Hellström-Lindberg Karolinska University Hospital
Pierre Fenaux
Pierre Fenaux Université Paris Cité
Guillermo Sanz
Guillermo Sanz Hospital Universitari i Politècnic La Fe
Arnold Ganser
Arnold Ganser Hannover Medical School

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