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D-Index & Metrics

Biology and Biochemistry

D-Index
52
Citations
15998
World Ranking
16462
National Ranking
6814

Overview

Tan A. Ince is affiliated with Cornell University in the United States and has contributed extensively to research in biochemistry, genetics, molecular biology, and medicine. Their work spans several subfields, including oncology, molecular biology, biomedical engineering, cancer research, and radiology, nuclear medicine, and imaging.

Their research primarily focuses on cancer cells and metastasis, cancer genomics and diagnostics, estrogen and related hormone effects, cytokine signaling pathways and interactions, cancer-related molecular pathways, protein degradation and inhibitors, and epigenetics and DNA methylation.

Ince has published multiple papers across several high-profile journals. Some recent works include:

  • "The Major Pre- and Postmenopausal Estrogens Play Opposing Roles in Obesity-Driven Mammary Inflammation and Breast Cancer Development," 2020, Cell Metabolism
  • "Aptamers against mouse and human tumor-infiltrating myeloid cells as reagents for targeted chemotherapy," 2020, Science Translational Medicine
  • "BET, SRC, and BCL2 family inhibitors are synergistic drug combinations with PARP inhibitors in ovarian cancer," 2020, EBioMedicine
  • "Transient commensal clonal interactions can drive tumor metastasis," 2020, Nature Communications
  • "ZNF92, an unexplored transcription factor with remarkably distinct breast cancer over-expression associated with prognosis and cell-of-origin," 2022, npj Breast Cancer

Academic collaboration plays a significant role in Ince's work. Frequent coauthors include Mohamed Omar, Luigi Marchionni, Rulla M. Tamimi, Joyce M. Slingerland, and J. Chuck Harrell. These collaborations have contributed to their productive output in oncology and cancer research.

Ince's publications appear regularly in well-recognized venues, with notable frequency in Nature Communications and Cancer Research. Other venues include Cell Metabolism, Science Translational Medicine, and npj Breast Cancer.

Best Publications

  • Reprogramming of human somatic cells to pluripotency with defined factors

    In Hyun Park;In Hyun Park;Rui Zhao;Rui Zhao;Jason A. West;Jason A. West;Akiko Yabuuchi;Akiko Yabuuchi

  • HSF1 Drives a Transcriptional Program Distinct from Heat Shock to Support Highly Malignant Human Cancers

    Marc L. Mendillo;Sandro Santagata;Sandro Santagata;Martina Koeva;George W. Bell

  • Live cell imaging distinguishes bona fide human iPS cells from partially reprogrammed cells

    Elayne M. Chan;Sutheera Ratanasirintrawoot;Sutheera Ratanasirintrawoot;In Hyun Park;Philip D. Manos;Philip D. Manos

  • The distal fallopian tube: a new model for pelvic serous carcinogenesis.

    Christopher P. Crum;Ronny Drapkin;Alexander Miron;Tan A. Ince

  • Systemic Endocrine Instigation of Indolent Tumor Growth Requires Osteopontin

    Sandra S. McAllister;Ann M. Gifford;Ashley L. Greiner;Ashley L. Greiner;Stephen P. Kelleher;Stephen P. Kelleher

  • Growth-Inhibitory and Tumor- Suppressive Functions of p53 Depend on Its Repression of CD44 Expression

    Samuel Godar;Tan A. Ince;Tan A. Ince;George W. Bell;David Feldser

  • Ras modulates Myc activity to repress thrombospondin-1 expression and increase tumor angiogenesis.

    Randolph S. Watnick;Yi Ning Cheng;Annapoorni Rangarajan;Tan A. Ince;Tan A. Ince

  • Transformation of Different Human Breast Epithelial Cell Types Leads to Distinct Tumor Phenotypes

    Tan A. Ince;Andrea L. Richardson;Andrea L. Richardson;George W. Bell;Maki Saitoh

  • Loss of p63 expression is associated with tumor progression in bladder cancer.

    Marshall J. Urist;Charles J. Di Como;Ming Lan Lu;Elizabeth Charytonowicz

  • High levels of nuclear heat-shock factor 1 (HSF1) are associated with poor prognosis in breast cancer

    Sandro Santagata;Rong Hu;Nancy U. Lin;Marc L. Mendillo

  • Fatty acid binding protein 4 is a target of VEGF and a regulator of cell proliferation in endothelial cells

    Harun Elmasri;Cagatay Karaaslan;Yaroslav Teper;Elisa Ghelfi

  • Ovarian cancer spheroids use myosin-generated force to clear the mesothelium

    Marcin P. Iwanicki;Rachel A. Davidowitz;Mei Rosa Ng;Achim Besser

  • Molecular identification of latent precancers in histologically normal endometrium.

    George L. Mutter;Tan A. Ince;Jan P.A. Baak;Jan P.A. Baak;Gregory A. Kust

  • Reference-free deconvolution of DNA methylation data and mediation by cell composition effects

    E. Andres Houseman;Molly L. Kile;David C. Christiani;Tan A. Ince

  • Taxonomy of breast cancer based on normal cell phenotype predicts outcome

    Sandro Santagata;Ankita Thakkar;Ayse Ergonul;Bin Wang

  • Transcriptional repression by p53 through direct binding to a novel DNA element.

    Robert A. Johnson;Robert A. Johnson;Tan A. Ince;Kathleen W. Scotto;Kathleen W. Scotto

  • A Genome-wide siRNA Screen Identifies Proteasome Addiction as a Vulnerability of Basal-like Triple-Negative Breast Cancer Cells

    Fabio Petrocca;Fabio Petrocca;Gabriel Altschuler;Shen Mynn Tan;Shen Mynn Tan;Marc L. Mendillo

  • Differentiation of NUT Midline Carcinoma by Epigenomic Reprogramming

    Brian E. Schwartz;Matthias D. Hofer;Madeleine E. Lemieux;Daniel E. Bauer

  • Characterization of twenty-five ovarian tumour cell lines that phenocopy primary tumours

    Tan A. Ince;Aurea D. Sousa;Michelle A. Jones;J. Chuck Harrell

  • A Conserved Downstream Element Defines a New Class of RNA Polymerase II Promoters

    Tan A. Ince;Kathleen W. Scotto

Frequent Co-Authors

Christopher P. Crum
Christopher P. Crum Brigham and Women's Hospital
Joan S. Brugge
Joan S. Brugge Harvard University
Gordon B. Mills
Gordon B. Mills Oregon Health & Science University
Sandro Santagata
Sandro Santagata Brigham and Women's Hospital
Ronny Drapkin
Ronny Drapkin University of Pennsylvania
George Q. Daley
George Q. Daley Boston Children's Hospital
Rulla M. Tamimi
Rulla M. Tamimi Cornell University
Andrea L. Richardson
Andrea L. Richardson Johns Hopkins University

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