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Stephen D. Skaper

Stephen D. Skaper

D-Index & Metrics

Biology and Biochemistry

D-Index
82
Citations
21635
World Ranking
3732
National Ranking
120

Overview

Stephen D. Skaper is affiliated with the University of Victoria in Canada and contributes actively to research primarily within the fields of Neuroscience and Medicine. Their work spans several subfields including Neurology, Immunology, Sensory Systems, Molecular Biology, and Physiology.

Their research focuses on several main topics, notably:

  • Mast cells and histamine
  • Olfactory and Sensory Function Studies
  • Receptor Mechanisms and Signaling
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Alzheimer's disease research and treatments
  • Tryptophan and brain disorders
  • Acute Ischemic Stroke Management

Skaper has published in a variety of scientific venues, which include:

  • Progress in brain research
  • Frontiers in Cellular Neuroscience
  • The Journal of Physiology

Frequent co-authors include Aruna Sharma, Dafin F. Mureșanu, Ranjana Patnaik, Preeti K. Menon, and Z. Ryan Tian, reflecting collaborative research efforts across multiple studies.

Recent publications authored or co-authored by Skaper cover topics related to neurodegenerative and inflammatory diseases as well as brain physiology. Notable papers include:

  • "REMOVED: Histamine H3 and H4 receptors modulate Parkinson's disease induced brain pathology. Neuroprotective effects of nanowired BF-2649 and clobenpropit with anti-histamine-antibody therapy" (2021, Progress in brain research)
  • "Corrigendum: An Inflammation-Centric View of Neurological Disease: Beyond the Neuron" (2020, Frontiers in Cellular Neuroscience)
  • "Decoding platelet loss in the hypoxic brain: What could go wrong?" (2025, The Journal of Physiology)

Across these works, the scientific focus extends into both basic and applied aspects of neurological disease mechanisms, including the roles of inflammatory cells, receptor signaling, and tissue responses in brain disorders.

Best Publications

  • Nerve growth factor : from neurotrophin to neurokine

    Rita Levi-Montalcini;Stephen D. Skaper;Roberto Dal Toso;Lucia Petrelli

  • Brain injury causes a time-dependent increase in neuronotrophic activity at the lesion site.

    M. Nieto-Sampedro;Ellen R. Lewis;Carl W. Cotman;Marston Manthorpe

  • An Inflammation-Centric View of Neurological Disease: Beyond the Neuron.

    Stephen D. Skaper;Laura Facci;Morena Zusso;Pietro Giusti

  • Basic fibroblast growth factor promotes the survival and development of mesencephalic neurons in culture.

    G. Ferrari;M.-C. Minozzi;G. Toffano;A. Leon

  • Selective survival of neurons from chick embryo sensory ganglionic dissociates utilizing serum-free supplemented medium.

    Jane E. Bottenstein;Stephen D. Skaper;Silvio S. Varon;Gordon H. Sato

  • The P2X7 purinergic receptor: from physiology to neurological disorders

    Stephen D. Skaper;Patrizia Debetto;Pietro Giusti

  • The neurotrophin family of neurotrophic factors: an overview.

    Stephen D. Skaper

  • Alpha-synuclein and Parkinson's disease.

    Alessandra Recchia;Patrizia Debetto;Alessandro Negro;Diego Guidolin

  • Purification of adult rat sciatic nerve ciliary neuronotrophic factor

    Marston Manthorpe;Stephen D. Skaper;Lawrence R. Williams;Silvio Varon

  • An automated colorimetric microassay for neuronotrophic factors.

    Marston Manthorpe;Roberto Fagnani;Stephen D. Skaper;Silvio Varon

  • Microglia and mast cells: two tracks on the road to neuroinflammation

    Stephen D. Skaper;Pietro Giusti;Laura Facci

  • Mast cells, glia and neuroinflammation: partners in crime?

    Stephen D Skaper;Laura Facci;Pietro Giusti

  • P2X7 receptors: channels, pores and more.

    C. Volonte;S. Apolloni;S. D. Skaper;G. Burnstock

  • Quercetin protects cutaneous tissue-associated cell types including sensory neurons from oxidative stress induced by glutathione depletion: cooperative effects of ascorbic acid

    Stephen D Skaper;Michele Fabris;Vanni Ferrari;Maurizio Dalle Carbonare

  • Neurotrophins Rescue Cerebellar Granule Neurons from Oxidative Stress‐Mediated Apoptotic Death: Selective Involvement of Phosphatidylinositol 3‐Kinase and the Mitogen‐Activated Protein Kinase Pathway

    Stephen D. Skaper;Maura Floreani;Alessandro Negro;Laura Facci

  • Neuronotrophic activities accumulate in vivo within silicone nerve regeneration chambers.

    Frank M. Longo;Frank M. Longo;Marston Manthorpe;Marston Manthorpe;Stephen D. Skaper;Stephen D. Skaper;Go¨ran Lundborg

  • MAPK-activated Protein Kinase 2 Deficiency in Microglia Inhibits Pro-inflammatory Mediator Release and Resultant Neurotoxicity RELEVANCE TO NEUROINFLAMMATION IN A TRANSGENIC MOUSE MODEL OF ALZHEIMER DISEASE

    Ainsley A. Culbert;Stephen D. Skaper;David R. Howlett;Nicholas A. Evans

  • Update of the NGF saga

    Rita Levi-Montalcini;Roberto Dal Toso;Federica della Valle;Stephen D. Skaper

  • Trophic activities for dorsal root and sympathetic ganglionic neurons in media conditioned by Schwann and other peripheral cells.

    Silvio Varon;Stephen D. Skaper;Marston Manthorpe

  • Selective small-molecule inhibitors of glycogen synthase kinase-3 activity protect primary neurones from death: Selective GSK-3 inhibitors prevent neuronal death

    Darren A. E. Cross;Ainsley A. Culbert;Katy A. Chalmers;Laura Facci

Frequent Co-Authors

Silvio Varon
Silvio Varon University of California, San Diego
Marston Manthorpe
Marston Manthorpe Vical (United States)
George E. Davis
George E. Davis University of South Florida
Diego Guidolin
Diego Guidolin University of Padua
Harriet Baker
Harriet Baker Cornell University
Tong H. Joh
Tong H. Joh Cornell University
Donald J. Reis
Donald J. Reis Cornell University
Tullio Pozzan
Tullio Pozzan University of Padua
Carl W. Cotman
Carl W. Cotman University of California, Irvine
Hisanori Suzuki
Hisanori Suzuki University of Verona

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