World's Best Scientists 2026 revealed!

D-Index & Metrics

Immunology

D-Index
48
Citations
17515
World Ranking
4378
National Ranking
1986

Overview

Stephen A. Migueles is affiliated with the National Institutes of Health in the United States. Their research primarily focuses on immunology, microbiology, and medicine, contributing extensively to the fields of HIV research and treatment, immune cell function and interaction, and infectious diseases.

Their published work spans several specialized subfields including immunology, virology, infectious diseases, epidemiology, and genetics. Central topics in their scientific portfolio include HIV/AIDS drug development and treatment, T-cell and B-cell immunology, HIV/AIDS research and interventions, cytomegalovirus and herpesvirus research, and virus-based gene therapy research.

Stephen A. Migueles has contributed to research appearing in multiple journals. Notable publication venues include:

  • Journal of Virology
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Medicine
  • Journal of Clinical Investigation
  • JCI Insight

Selected recent papers authored or co-authored by Migueles include:

  • "Safety and tolerability of AAV8 delivery of a broadly neutralizing antibody in adults living with HIV: a phase 1, dose-escalation trial," 2022, published in Nature Medicine
  • "A replication-competent adenovirus-vectored influenza vaccine induces durable systemic and mucosal immunity," 2021, Journal of Clinical Investigation
  • "Naive infection predicts reservoir diversity and is a formidable hurdle to HIV eradication," 2021, JCI Insight
  • "Evaluating a New Class of AKT/mTOR Activators for HIV Latency-Reversing Activity Ex Vivo and In Vivo," 2021, Journal of Virology
  • "Lost in Translation: Lack of CD4 Expression due to a Novel Genetic Defect," 2021, The Journal of Infectious Diseases

The scientist frequently collaborates with a range of co-authors including:

  • April Poole
  • Mark Connors
  • C. Jason Liang
  • Addison J. Ward
  • Daniel C. Rogan

Overall, their research contributes to understanding mechanisms of immune response and viral latency, with a significant focus on HIV and related infectious agents. This work provides insight into therapeutic strategies and vaccine development within their main areas of study.

Best Publications

  • HIV nonprogressors preferentially maintain highly functional HIV-specific CD8+ T-cells

    Michael R. Betts;Martha C. Nason;Sadie M. West;Stephen C. De Rosa

  • HLA B*5701 is highly associated with restriction of virus replication in a subgroup of HIV-infected long term nonprogressors.

    Stephen A. Migueles;M. Shirin Sabbaghian;W. Lesley Shupert;Maria P. Bettinotti

  • Expression of CD57 defines replicative senescence and antigen-induced apoptotic death of CD8+ T cells

    Jason M. Brenchley;Nitin J. Karandikar;Michael R. Betts;David R. Ambrozak

  • HIV-specific CD8+ T cell proliferation is coupled to perforin expression and is maintained in nonprogressors

    Stephen A. Migueles;Alisha C. Laborico;W. Lesley Shupert;M. Shirin Sabbaghian

  • Broad and potent neutralization of HIV-1 by a gp41-specific human antibody

    Jinghe Huang;Gilad Ofek;Leo Laub;Mark K. Louder

  • Lytic Granule Loading of CD8+ T Cells Is Required for HIV-Infected Cell Elimination Associated with Immune Control

    Stephen A. Migueles;Christine M. Osborne;Cassandra Royce;Alex A. Compton

  • T-Cell Subsets That Harbor Human Immunodeficiency Virus (HIV) In Vivo: Implications for HIV Pathogenesis

    Jason M. Brenchley;Brenna J. Hill;David R. Ambrozak;David A. Price

  • Virologic effects of broadly neutralizing antibody VRC01 administration during chronic HIV-1 infection

    Rebecca M. Lynch;Eli Boritz;Emily E. Coates;Adam DeZure

  • Broad and potent HIV-1 neutralization by a human antibody that binds the gp41–gp120 interface

    Jinghe Huang;Byong H. Kang;Marie Pancera;Jeong Hyun Lee

  • Broad HIV-1 neutralization mediated by CD4-binding site antibodies

    Yuxing Li;Stephen A Migueles;Brent Welcher;Krisha Svehla

  • Avidity for antigen shapes clonal dominance in CD8 + T cell populations specific for persistent DNA viruses

    David A. Price;Jason M. Brenchley;Laura E. Ruff;Michael R. Betts

  • Frequency and Phenotype of Human Immunodeficiency Virus Envelope-Specific B Cells from Patients with Broadly Cross-Neutralizing Antibodies

    Nicole A. Doria-Rose;Rachel M. Klein;Maura M. Manion;Sijy O'Dell

  • Identification of a CD4-Binding-Site Antibody to HIV that Evolved Near-Pan Neutralization Breadth.

    Jinghe Huang;Byong H. Kang;Elise Ishida;Tongqing Zhou

  • Breadth of Human Immunodeficiency Virus-Specific Neutralizing Activity in Sera: Clustering Analysis and Association with Clinical Variables

    Nicole A. Doria-Rose;Rachel M. Klein;Marcus G. Daniels;Sijy O'Dell

  • Maintenance of large numbers of virus-specific CD8+ T cells in HIV-infected progressors and long-term nonprogressors.

    Juan C. Gea-Banacloche;Stephen A. Migueles;Lisa Martino;W. Lesley Shupert

  • Analysis of Neutralization Specificities in Polyclonal Sera Derived from Human Immunodeficiency Virus Type 1-Infected Individuals

    Yuxing Li;Krisha Svehla;Mark K. Louder;Diane Wycuff

  • Delineating antibody recognition in polyclonal sera from patterns of HIV-1 isolate neutralization.

    Ivelin S. Georgiev;Nicole A. Doria-Rose;Tongqing Zhou;Young Do Kwon

  • Defective Human Immunodeficiency Virus-Specific CD8+ T-Cell Polyfunctionality, Proliferation, and Cytotoxicity Are Not Restored by Antiretroviral Therapy

    Stephen A. Migueles;Kristin A. Weeks;Eric Nou;Amy M. Berkley

  • The Differential Ability of HLA B*5701+ Long-Term Nonprogressors and Progressors To Restrict Human Immunodeficiency Virus Replication Is Not Caused by Loss of Recognition of Autologous Viral gag Sequences

    Stephen A. Migueles;Alisha C. Laborico;Hiromi Imamichi;W. Lesley Shupert

  • Diminished Proliferation of Human Immunodeficiency Virus-Specific CD4+ T Cells Is Associated with Diminished Interleukin-2 (IL-2) Production and Is Recovered by Exogenous IL-2

    Christiana Iyasere;John C. Tilton;Alison J. Johnson;Souheil Younes

Frequent Co-Authors

Mark Connors
Mark Connors National Institute of Allergy and Infectious Diseases
Claire W. Hallahan
Claire W. Hallahan National Institute of Allergy and Infectious Diseases
Nicole A. Doria-Rose
Nicole A. Doria-Rose National Institute of Allergy and Infectious Diseases
John R. Mascola
John R. Mascola ModeX Therapeutics
Robert T. Bailer
Robert T. Bailer National Institute of Allergy and Infectious Diseases
Julia A. Metcalf
Julia A. Metcalf National Institute of Allergy and Infectious Diseases
Daniel C. Douek
Daniel C. Douek National Institute of Allergy and Infectious Diseases
Richard A. Koup
Richard A. Koup National Institute of Allergy and Infectious Diseases
Richard T. Wyatt
Richard T. Wyatt Scripps Research Institute
Tae-Wook Chun
Tae-Wook Chun National Institute of Allergy and Infectious Diseases

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

For those interested in Immunology, pursuing related health science degrees can open diverse career pathways. Many students look for programs that balance quality education with manageable admission requirements. Accelerated nursing programs offer a fast-track to becoming a registered nurse, providing foundational healthcare knowledge beneficial to immunology-related fields. If you seek options that are more accessible, accredited LPN programs easy to get into might be an excellent starting point, allowing quicker entry into the nursing workforce.

Advancing your career, nurse practitioner programs with easy admission present opportunities to specialize further while maintaining a flexible study approach. These programs equip graduates with skills to assess and treat patients, a vital aspect in immunology-related healthcare roles.

For those focusing on mental health, top PMHNP programs with the best clinical placement rates combine strong clinical experience with online accessibility. This pathway integrates mental health expertise with immunological knowledge, supporting holistic patient care.

Exploring these related online degrees can complement your understanding of Immunology while expanding your professional options in healthcare.

accelerated nursing programs, accredited lpn programs easy to get into, nurse practitioner programs with easy admission, and top pmhnp programs.

Best Scientists Citing Stephen A. Migueles

Trending Scientists