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Shigeo Okabe

Shigeo Okabe

D-Index & Metrics

Biology and Biochemistry

D-Index
57
Citations
15619
World Ranking
13623
National Ranking
954

Overview

Shigeo Okabe is affiliated with the University of Tokyo in Japan and has contributed extensively to the fields of biochemistry, genetics, molecular biology, and neuroscience. Their research spans 37 publications in biochemistry, genetics, and molecular biology and 36 in neuroscience, with significant focus on subfields such as molecular biology, cellular and molecular neuroscience, biophysics, cognitive neuroscience, and neurology.

The topics of their work include:

  • Neuroscience and neuropharmacology research
  • Advanced fluorescence microscopy techniques
  • Neuroinflammation and neurodegeneration mechanisms
  • Genetics and neurodevelopmental disorders
  • Immune cells in cancer
  • Photoreceptor and optogenetics research
  • Cellular mechanics and interactions

Okabe has frequently published in venues such as Microscopy and the Journal of Visualized Experiments, each hosting four of their papers. Other key publication venues include bioRxiv (Cold Spring Harbor Laboratory) with three papers, Neuron and Nature Communications with two papers each.

Among the recent papers authored or co-authored by Okabe are:

  • "International Brain Initiative: An Innovative Framework for Coordinated Global Brain Research Efforts," 2020, Neuron
  • "Canonical versus non-canonical transsynaptic signaling of neuroligin 3 tunes development of sociality in mice," 2021, Nature Communications
  • "Regulation of actin dynamics in dendritic spines: Nanostructure, molecular mobility, and signaling mechanisms," 2020, Molecular and Cellular Neuroscience
  • "Geometry and the Organizational Principle of Spine Synapses along a Dendrite," 2020, eNeuro
  • "Large-scale animal model study uncovers altered brain pH and lactate levels as a transdiagnostic endophenotype of neuropsychiatric disorders involving cognitive impairment," 2024, eLife

Okabe has collaborated frequently with several co-authors, including Hisato Maruoka and Shinji Urata, each having six joint publications with them, as well as Ryosuke Kamei with five publications, and Keizo Takao and Katsuhiko Tabuchi, each contributing to four joint works.

Best Publications

  • Regeneration of Hippocampal Pyramidal Neurons after Ischemic Brain Injury by Recruitment of Endogenous Neural Progenitors

    Hirofumi Nakatomi;Toshihiko Kuriu;Shigeo Okabe;Shin ichi Yamamoto

  • Near-infrared deep brain stimulation via upconversion nanoparticle–mediated optogenetics

    Shuo Chen;Adam Z. Weitemier;Xiao Zeng;Linmeng He

  • Development of neuronal precursor cells and functional postmitotic neurons from embryonic stem cells in vitro

    Shigeo Okabe;Karin Forsberg-Nilsson;A. Cyril Spiro;Menahem Segal

  • Altered microtubule organization in small-calibre axons of mice lacking tau protein

    A. Harada;K. Oguchi;S. Okabe;J. Kuno

  • Tau proteins: the molecular structure and mode of binding on microtubules.

    N Hirokawa;Y Shiomura;S Okabe

  • Increased microtubule stability and alpha tubulin acetylation in cells transfected with microtubule-associated proteins MAP1B, MAP2 or tau.

    R Takemura;S Okabe;T Umeyama;Y Kanai

  • In vitro-Generated Neural Precursors Participate in Mammalian Brain Development

    O. Brustle;A. C. Spiro;K. Karram;K. Choudhary

  • Spine Formation and Correlated Assembly of Presynaptic and Postsynaptic Molecules

    Shigeo Okabe;Akiko Miwa;Haruo Okado

  • The RNA binding protein TLS is translocated to dendritic spines by mGluR5 activation and regulates spine morphology.

    Ritsuko Fujii;Shigeo Okabe;Shigeo Okabe;Tomoe Urushido;Kiyoshi Inoue

  • Continual remodeling of postsynaptic density and its regulation by synaptic activity

    Shigeo Okabe;Hong-Duck Kim;Akiko Miwa;Toshihiko Kuriu

  • Direct Astrocytic Contacts Regulate Local Maturation of Dendritic Spines

    Hideko Nishida;Shigeo Okabe

  • Molecular anatomy of the postsynaptic density.

    Shigeo Okabe

  • Differential Control of Postsynaptic Density Scaffolds via Actin-Dependent and -Independent Mechanisms

    Toshihiko Kuriu;Akihiro Inoue;Haruhiko Bito;Kenji Sobue

  • Alternative splicing of the C-terminal domain regulates cell surface expression of the NMDA receptor NR1 subunit.

    Shigeo Okabe;Akiko Miwa;Haruo Okado

  • Determination of absolute protein numbers in single synapses by a GFP-based calibration technique.

    Yoshiko Sugiyama;Izumi Kawabata;Kenji Sobue;Shigeo Okabe

  • Turnover of fluorescently labelled tubulin and actin in the axon

    Shigeo Okabe;Nobutaka Hirokawa

  • Myosin-Va Facilitates the Accumulation of mRNA/Protein Complex in Dendritic Spines

    Atsushi Yoshimura;Ritsuko Fujii;Yasuhito Watanabe;Yasuhito Watanabe;Shigeo Okabe

  • Actin dynamics in growth cones

    Shigeo Okabe;Nobutaka Hirokawa

  • POU transcription factors control expression of CNS stem cell-specific genes

    R. Josephson;T. Muller;J. Pickel;S. Okabe

  • Kinase-Dead Knock-In Mouse Reveals an Essential Role of Kinase Activity of Ca2+/Calmodulin-Dependent Protein Kinase IIα in Dendritic Spine Enlargement, Long-Term Potentiation, and Learning

    Yoko Yamagata;Shizuka Kobayashi;Tatsuya Umeda;Akihiro Inoue

Frequent Co-Authors

Nobutaka Hirokawa
Nobutaka Hirokawa University of Tokyo
Akihiro Kusumi
Akihiro Kusumi Okinawa Institute of Science and Technology
Toru Takumi
Toru Takumi Kobe University
Ronald D. G. McKay
Ronald D. G. McKay Lieber Institute for Brain Development
Masahiko Watanabe
Masahiko Watanabe Hokkaido University
Kenji Sobue
Kenji Sobue Iwate Medical University
Hiroaki Hori
Hiroaki Hori Tokyo Medical and Dental University
Hiroshi Kunugi
Hiroshi Kunugi Teikyo University
Toshiya Manabe
Toshiya Manabe University of Tokyo
Michisuke Yuzaki
Michisuke Yuzaki Keio University

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