Roland Brandt

Research.com Recognitions

• 1969 - Fellow of Alfred P. Sloan Foundation

Overview

Best Publications

• Interaction of tau with the neural plasma membrane mediated by tau's amino-terminal projection domain.

  R Brandt;J Léger;G Lee

  811
  Citations

• CD95 ligand (Fas-L/APO-1L) and tumor necrosis factor-related apoptosis-inducing ligand mediate ischemia-induced apoptosis in neurons.

  Ana Martin-Villalba;Ingrid Herr;Irmela Jeremias;Michael Hahne

  608
  Citations

• Molecular Interactions among Protein Phosphatase 2A, Tau, and Microtubules IMPLICATIONS FOR THE REGULATION OF TAU PHOSPHORYLATION AND THE DEVELOPMENT OF TAUOPATHIES

  Estelle Sontag;Viyada Nunbhakdi-Craig;Gloria Lee;Roland Brandt

  389
  Citations

• Tau alteration and neuronal degeneration in tauopathies: mechanisms and models

  Roland Brandt;Monika Hundelt;Neelam Shahani

  320
  Citations

• Process Outgrowth of Oligodendrocytes Is Promoted by Interaction of Fyn Kinase with the Cytoskeletal Protein Tau

  Corinna Klein;Eva-Maria Krämer;Anne-Marie Cardine;Burkhardt Schraven

  315
  Citations

• Tau Binds to the Distal Axon Early in Development of Polarity in a Microtubule- and Microfilament-Dependent Manner

  Martina Kempf;Albrecht Clement;Andreas Faissner;Gloria Lee

  313
  Citations

• Functional organization of microtubule-associated protein tau. Identification of regions which affect microtubule growth, nucleation, and bundle formation in vitro.

  R. Brandt;G. Lee

  309
  Citations

• Tau-Mediated Cytotoxicity in a Pseudohyperphosphorylation Model of Alzheimer's Disease

  Thomas Fath;Jochen Eidenmüller;Roland Brandt;Roland Brandt

  287
  Citations

• Interaction of tau with the neural membrane cortex is regulated by phosphorylation at sites that are modified in paired helical filaments.

  Thorsten Maas;Jochen Eidenmüller;Roland Brandt

  278
  Citations

• Functions and malfunctions of the tau proteins

  N. Shahani;R. Brandt

  252
  Citations

• Tau Biology and Tau-Directed Therapies for Alzheimer’s Disease

  Lidia Bakota;Roland Brandt

  179
  Citations

• Divergent pathways mediate spine alterations and cell death induced by amyloid-beta, wild-type tau, and R406W tau

  Christian Tackenberg;Roland Brandt

  175
  Citations

• Conversion of serine to aspartate imitates phosphorylation-induced changes in the structure and function of microtubule-associated protein tau.

  Jocelyne Léger;Martina Kempf;Gloria Lee;Roland Brandt

  165
  Citations

• Single-molecule tracking of tau reveals fast kiss-and-hop interaction with microtubules in living neurons

  Dennis Janning;Maxim Igaev;Frederik Sündermann;Jörg Brühmann

  164
  Citations

• The frontotemporal dementia mutation R406W blocks tau’s interaction with the membrane in an annexin A2–dependent manner

  Anne Gauthier-Kemper;Carina Weissmann;Nataliya Golovyashkina;Zsofia Sebö-Lemke

  151
  Citations

• Phosphorylation-mimicking glutamate clusters in the proline-rich region are sufficient to simulate the functional deficiencies of hyperphosphorylated tau protein.

  Jochen Eidenmüller;Thomas Fath;Thorsten Maas;Madeline Pool

  149
  Citations

• Structural and Functional Implications of Tau Hyperphosphorylation: Information from Phosphorylation-Mimicking Mutated Tau Proteins†

  Jochen Eidenmuller;Thomas Fath;Andrea Hellwig;Jennifer Reed

  147
  Citations

• A Caenorhabditis elegans model of tau hyperphosphorylation: Induction of developmental defects by transgenic overexpression of Alzheimer's disease-like modified tau

  Roland Brandt;Aikaterini Gergou;Irene Wacker;Thomas Fath;Thomas Fath

  143
  Citations

• NMDA receptor subunit composition determines beta-amyloid-induced neurodegeneration and synaptic loss.

  C Tackenberg;S Grinschgl;A Trutzel;A C Santuccione

  142
  Citations

• Stabilization of hyperdynamic microtubules is neuroprotective in amyotrophic lateral sclerosis.

  Patrizia Fanara;Jayee Banerjee;Rommel V. Hueck;Macha R. Harper

  141
  Citations