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Chemistry

D-Index
67
Citations
16909
World Ranking
6863
National Ranking
391

Overview

Ian R. Baxendale is affiliated with Durham University in the United Kingdom. Their research primarily spans the fields of Materials Science and Chemistry, with a substantial focus on Materials Chemistry and Organic Chemistry.

The scientist's recent research publications cover a variety of topics and have appeared in numerous scientific journals. Notable papers include:

  • A comprehensive review of flow chemistry techniques tailored to the flavours and fragrances industries, 2021, Beilstein Journal of Organic Chemistry
  • Protein domain-based prediction of drug/compound-target interactions and experimental validation on LIM kinases, 2021, PLoS Computational Biology
  • Continuous-Flow Hofmann Rearrangement Using Trichloroisocyanuric Acid for the Preparation of 2-Benzoxazolinone, 2022, Organic Process Research & Development
  • Rearrangement of 3-Hydroxyazetidines into 2-Oxazolines, 2020, The Journal of Organic Chemistry
  • Benzo[1,2,3]dithiazole Compounds: A History of Synthesis and Their Renewed Applicability in Materials and Synthetic Chemistry, Originating from the Herz Reaction, 2021, Reactions

Baxendale's research covers major topics such as Crystallization and Solubility Studies, X-ray Diffraction in Crystallography, Analytical Chemistry and Chromatography, Innovative Microfluidic and Catalytic Techniques Innovation, Oxidative Organic Chemistry Reactions, Computational Drug Discovery Methods, and Microbial Natural Products and Biosynthesis.

Frequent collaborators include Guido Gambacorta, Michele Ruggeri, Amanda W. Dombrowski, Stevan W. Djurić, and James S. Sharley, indicating active collaboration with other researchers across multiple projects.

Their work has been published repeatedly in specific venues, with notable frequent publication in:

  • The Cambridge Structural Database
  • Molbank
  • Zenodo (CERN European Organization for Nuclear Research)
  • SSRN Electronic Journal
  • The Journal of Organic Chemistry

The research contributions of Ian R. Baxendale integrate advanced techniques in flow chemistry, crystallography, and computational drug discovery, reflecting interdisciplinary expertise that bridges experimental and theoretical approaches in chemistry and materials science.

Best Publications

  • Multi-step organic synthesis using solid-supported reagents and scavengers: a new paradigm in chemical library generation

    Steven V. Ley;Ian R. Baxendale;Robert N. Bream;Philip S. Jackson

  • An overview of the synthetic routes to the best selling drugs containing 6-membered heterocycles

    Marcus Baumann;Ian R Baxendale

  • The molecular basis for selective inhibition of unconventional mRNA splicing by an IRE1-binding small molecule

    Benedict C. S. Cross;Peter J. Bond;Pawel G. Sadowski;Babal Kant Jha

  • An overview of the key routes to the best selling 5-membered ring heterocyclic pharmaceuticals.

    Marcus Baumann;Ian R Baxendale;Steven V Ley;Nikzad Nikbin

  • The Use of Gases in Flow Synthesis

    Carl J. Mallia;Ian R. Baxendale

  • A flow process for the multi-step synthesis of the alkaloid natural product oxomaritidine: a new paradigm for molecular assembly.

    Ian R. Baxendale;Jon Deeley;Charlotte M. Griffiths-Jones;Steven V. Ley

  • Flow Ozonolysis Using a Semipermeable Teflon AF-2400 Membrane To Effect Gas−Liquid Contact

    Matthew O’Brien;Ian R. Baxendale;Steven V. Ley

  • The synthesis of active pharmaceutical ingredients (APIs) using continuous flow chemistry.

    Marcus Baumann;Ian R Baxendale

  • ReactIR Flow Cell: A New Analytical Tool for Continuous Flow Chemical Processing

    Catherine F. Carter;Heiko Lange;Steven V. Ley;Ian R. Baxendale

  • The integration of flow reactors into synthetic organic chemistry

    Ian R. Baxendale

  • Microwave-assisted Suzuki coupling reactions with an encapsulated palladium catalyst for batch and continuous-flow transformations.

    Ian R. Baxendale;Charlotte M. Griffiths-Jones;Steven V. Ley;Geoffrey K. Tranmer

  • New tools and concepts for modern organic synthesis

    Steven V. Ley;Ian R. Baxendale

  • Total syntheses of natural products containing spirocarbocycles

    Laura K. Smith;Ian R. Baxendale

  • The Continuous‐Flow Synthesis of Carboxylic Acids using CO2 in a Tube‐In‐Tube Gas Permeable Membrane Reactor

    Anastasios Polyzos;Matthew O'Brien;Trine P Petersen;Ian R Baxendale

  • Multistep Synthesis Using Modular Flow Reactors: Bestmann–Ohira Reagent for the Formation of Alkynes and Triazoles†

    Ian R. Baxendale;Steven V. Ley;Andrew C. Mansfield;Christopher D. Smith

  • A flow-based synthesis of imatinib: the API of Gleevec.

    Mark D. Hopkin;Ian R. Baxendale;Steven V. Ley

  • Hydrogenation in flow: Homogeneous and heterogeneous catalysis using Teflon AF-2400 to effect gas-liquid contact at elevated pressure†‡

    Matthew O'Brien;Nicholas Taylor;Anastasios Polyzos;Ian R. Baxendale

  • KMnO4-Mediated Oxidation as a Continuous Flow Process

    Jörg Sedelmeier;Steven V. Ley;Ian R. Baxendale;Marcus Baumann

  • Safe and Reliable Synthesis of Diazoketones and Quinoxalines in a Continuous Flow Reactor

    Laetitia J. Martin;Andreas L. Marzinzik;Steven V. Ley;Ian R. Baxendale

  • The flow synthesis of heterocycles for natural product and medicinal chemistry applications.

    Marcus Baumann;Ian R. Baxendale;Steven V. Ley

Frequent Co-Authors

Steven V. Ley
Steven V. Ley University of Cambridge
Andrei V. Malkov
Andrei V. Malkov Loughborough University
Duncan L. Browne
Duncan L. Browne University College London
Pavel Kočovský
Pavel Kočovský University of Glasgow
Volker Hessel
Volker Hessel University of Adelaide
Holger Löwe
Holger Löwe Johannes Gutenberg University of Mainz
Malcolm R. Mackley
Malcolm R. Mackley University of Cambridge
David Ron
David Ron University of Cambridge
Heather P. Harding
Heather P. Harding University of Cambridge

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