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D-Index & Metrics

Biology and Biochemistry

D-Index
73
Citations
29786
World Ranking
5805
National Ranking
2746

Overview

Ruth T. Yu is affiliated with the Salk Institute for Biological Studies in the United States. Their research primarily spans the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with a significant focus on Molecular Biology, Physiology, Epidemiology, Hepatology, and Immunology as subfields of study.

The scientist's work encompasses several main topics, including:

  • Adipose Tissue and Metabolism
  • Liver Disease Diagnosis and Treatment
  • Liver Disease and Transplantation
  • Immune Cell Function and Interaction
  • Epigenetics and DNA Methylation
  • Gut microbiota and health
  • Adipokines, Inflammation, and Metabolic Diseases

Ruth T. Yu has been published extensively in multiple scientific venues. The most frequent publication venues include:

  • Proceedings of the National Academy of Sciences
  • Nature
  • Cell Metabolism
  • Nature Metabolism
  • Cell Reports

Their recent notable papers demonstrate a focus on metabolic and immunological research as well as disease pathology and treatment responses. Selected recent publications are:

  • "Immune-evasive human islet-like organoids ameliorate diabetes", 2020, Nature
  • "A Universal Gut-Microbiome-Derived Signature Predicts Cirrhosis", 2020, Cell Metabolism
  • "Obesity alters pathology and treatment response in inflammatory disease", 2022, Nature
  • "FGF1 and insulin control lipolysis by convergent pathways", 2022, Cell Metabolism
  • "Obesity causes mitochondrial fragmentation and dysfunction in white adipocytes due to RalA activation", 2024, Nature Metabolism

Frequent collaborators in research projects include:

  • Michael Downes
  • Ronald M. Evans
  • Annette R. Atkins
  • Tae Gyu Oh
  • Christopher Liddle

Best Publications

  • Hotspots of aberrant epigenomic reprogramming in human induced pluripotent stem cells

    Ryan Lister;Mattia Pelizzola;Yasuyuki S. Kida;R. David Hawkins

  • Peroxisome-Proliferator-Activated Receptor δ Activates Fat Metabolism to Prevent Obesity

    Yong-Xu Wang;Chih-Hao Lee;Chih-Hao Lee;Sambath Tiep;Ruth T Yu

  • AMPK and PPARδ Agonists Are Exercise Mimetics

    Vihang A Narkar;Michael Downes;Ruth T. Yu;Emi Embler

  • Regulation of muscle fiber type and running endurance by PPARδ

    Yong Xu Wang;Chun Li Zhang;Ruth T. Yu;Helen K. Cho

  • Anatomical Profiling of Nuclear Receptor Expression Reveals a Hierarchical Transcriptional Network

    Angie L. Bookout;Yangsik Jeong;Michael Downes;Ruth T. Yu

  • Regulation of antibacterial defense in the small intestine by the nuclear bile acid receptor.

    Takeshi Inagaki;Antonio Moschetta;Youn Kyoung Lee;Li Peng

  • Regulation of circadian behaviour and metabolism by REV-ERB-α and REV-ERB-β

    Han Cho;Xuan Zhao;Megumi Hatori;Ruth T. Yu

  • Vitamin D Receptor-Mediated Stromal Reprogramming Suppresses Pancreatitis and Enhances Pancreatic Cancer Therapy

    Mara H. Sherman;Ruth T. Yu;Dannielle D. Engle;Ning Ding

  • Nuclear Receptor Expression Links the Circadian Clock to Metabolism

    Xiaoyong Yang;Michael Downes;Ruth T. Yu;Angie L. Bookout

  • Intestinal FXR agonism promotes adipose tissue browning and reduces obesity and insulin resistance

    Sungsoon Fang;Jae Myoung Suh;Shannon M Reilly;Elizabeth Yu

  • A Vitamin D Receptor/SMAD Genomic Circuit Gates Hepatic Fibrotic Response

    Ning Ding;Ruth T. Yu;Nanthakumar Subramaniam;Mara H. Sherman

  • Cryptochromes mediate rhythmic repression of the glucocorticoid receptor

    Katja A. Lamia;Katja A. Lamia;Stephanie J. Papp;Ruth T. Yu;Grant D. Barish

  • Class IIa histone deacetylases are hormone-activated regulators of FOXO and mammalian glucose homeostasis.

    Maria M. Mihaylova;Debbie S. Vasquez;Kim Ravnskjaer;Pierre-Damien Denechaud

  • Fibroblast Growth Factor-21 Regulates PPARγ Activity and the Antidiabetic Actions of Thiazolidinediones

    Paul A. Dutchak;Takeshi Katafuchi;Angie L. Bookout;Jang Hyun Choi

  • Expression and function of orphan nuclear receptor TLX in adult neural stem cells

    Yanhong Shi;D. Chichung Lie;Philippe Taupin;Kinichi Nakashima;Kinichi Nakashima

  • Inflammation-induced IgA + cells dismantle anti-liver cancer immunity

    Shabnam Shalapour;Xue Jia Lin;Xue Jia Lin;Ingmar N. Bastian;John Brain

  • An inhibitor of the protein kinases TBK1 and IKK-ɛ improves obesity-related metabolic dysfunctions in mice

    Shannon M. Reilly;Shian Huey Chiang;Shian Huey Chiang;Stuart J. Decker;Louise Chang

  • The starvation hormone, fibroblast growth factor-21, extends lifespan in mice

    Yuan Zhang;Yang Xie;Eric D Berglund;Katie Colbert Coate

  • FXR Regulates Intestinal Cancer Stem Cell Proliferation.

    Ting Fu;Sally Coulter;Eiji Yoshihara;Tae Gyu Oh

  • Orphan nuclear receptor TLX activates Wnt/beta-catenin signalling to stimulate neural stem cell proliferation and self-renewal.

    Qiuhao Qu;Guoqiang Sun;Wenwu Li;Su Yang

Frequent Co-Authors

Ronald M. Evans
Ronald M. Evans Salk Institute for Biological Studies
Michael Downes
Michael Downes Salk Institute for Biological Studies
Christopher Liddle
Christopher Liddle University of Sydney
Alan R. Saltiel
Alan R. Saltiel University of California, San Diego
David J. Mangelsdorf
David J. Mangelsdorf The University of Texas Southwestern Medical Center
Rohit Loomba
Rohit Loomba University of California, San Diego
Jerrold M. Olefsky
Jerrold M. Olefsky University of California, San Diego
Bernd Schnabl
Bernd Schnabl University of California, San Diego
David A. Brenner
David A. Brenner University of California, San Diego
Christopher Benner
Christopher Benner University of California, San Diego

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