Richard A. Lake

Best Publications

• Immunotherapy and chemotherapy — a practical partnership

  Richard A. Lake;Bruce W.S. Robinson

  781
  Citations

• Induction of Tumor Cell Apoptosis In Vivo Increases Tumor Antigen Cross-Presentation, Cross-Priming Rather than Cross-Tolerizing Host Tumor-Specific CD8 T Cells

  Anna K Nowak;Richard A Lake;Amanda L Marzo;Amanda L Marzo;Bernadette Maree Scott;Bernadette Maree Scott

  556
  Citations

• Synergy between chemotherapy and immunotherapy in the treatment of established murine solid tumors.

  Anna K Nowak;Bruce W S Robinson;Richard A Lake

  513
  Citations

• Tumor-specific CD4+ T cells have a major "post-licensing" role in CTL mediated anti-tumor immunity

  Amanda L. Marzo;Beverley F. Kinnear;Richard A. Lake;Jeffrey J. Frelinger

  468
  Citations

• Programmed Death Ligand 2 in Cancer-Induced Immune Suppression

  Esdy N. Rozali;Stanleyson V. Hato;Bruce W. Robinson;Richard A. Lake

  371
  Citations

• Gemcitabine Exerts a Selective Effect on the Humoral Immune Response Implications for Combination Chemo-immunotherapy

  Anna K Nowak;Bruce W S Robinson;Richard A Lake

  297
  Citations

• Dynamic versus static biomarkers in cancer immune checkpoint blockade: unravelling complexity.

  W. Joost Lesterhuis;Anthony Bosco;Michael J. Millward;Michael J. Millward;Michael Small;Michael Small

  241
  Citations

• Tumor Antigens are Constitutively Presented in the Draining Lymph Nodes

  Amanda L. Marzo;Richard A. Lake;David Lo;Linda Sherman

  217
  Citations

• Sensitization to immune checkpoint blockade through activation of a STAT1/NK axis in the tumor microenvironment

  Rachael M. Zemek;Emma De Jong;Wee Loong Chin;Wee Loong Chin;Iona S. Schuster;Iona S. Schuster;Iona S. Schuster

  204
  Citations

• Cancer chemotherapy: insights into cellular and tumor microenvironmental mechanisms of action

  Unknown

  193
  Citations

• Tumor eradication after cyclophosphamide depends on concurrent depletion of regulatory T cells: a role for cycling TNFR2-expressing effector-suppressor T cells in limiting effective chemotherapy

  Robbert G. van der Most;Robbert G. van der Most;Andrew J. Currie;Sathish Mahendran;Amy Prosser

  177
  Citations

• New approaches for mesothelioma: biologics, vaccines, gene therapy, and other novel agents.

  Anna K. Nowak;Richard A. Lake;Hedy Lee Kindler;Bruce W.S. Robinson

  164
  Citations

• Synergistic Effect of CTLA-4 Blockade and Cancer Chemotherapy in the Induction of Anti-Tumor Immunity

  W. Joost Lesterhuis;W. Joost Lesterhuis;Joanne Salmons;Anna K. Nowak;Anna K. Nowak;Esdy N. Rozali

  161
  Citations

• T-Cell Receptor Transgenic Analysis of Tumor-specific CD8 and CD4 Responses in the Eradication of Solid Tumors

  Amanda L. Marzo;Richard A. Lake;Bruce W. S. Robinson;Bernadette Scott

  161
  Citations

• Chemotherapy and immunotherapy: Mapping the road ahead

  Alistair M Cook;W Joost Lesterhuis;Anna K Nowak;Anna K Nowak;Richard A Lake

  140
  Citations

• Replication-restricted vaccinia as a cytokine gene therapy vector in cancer: Persistent transgene expression despite antibody generation

  Sutapa Mukherjee;Thomas Haenel;Robyn Himbeck;Bernadette Scott

  136
  Citations

• Immunogenic anti-cancer chemotherapy as an emerging concept

  Nicole M Haynes;Robbert G van der Most;Richard A Lake;Mark J Smyth

  127
  Citations

• Combined chemoimmunotherapy of solid tumours: improving vaccines?

  Anna K. Nowak;Richard A. Lake;Bruce W.S. Robinson

  126
  Citations

• Cyclophosphamide chemotherapy sensitizes tumor cells to TRAIL-dependent CD8 T cell-mediated immune attack resulting in suppression of tumor growth.

  Robbert G. van der Most;Andrew J. Currie;Amanda L. Cleaver;Joanne Salmons

  123
  Citations

• Cranking the immunologic engine with chemotherapy: using context to drive tumor antigen cross-presentation towards useful antitumor immunity.

  Robbert G. van der Most;Andrew Currie;Bruce W.S. Robinson;Richard A. Lake

  122
  Citations