World's Best Scientists 2026 revealed!

D-Index & Metrics

Immunology

D-Index
52
Citations
13703
World Ranking
4031
National Ranking
1841

Best Publications

  • Increasing the efficacy of CD20 antibody therapy through the engineering of a new type II anti-CD20 antibody with enhanced direct and immune effector cell–mediated B-cell cytotoxicity

    Ekkehard Mössner;Peter Brünker;Samuel Moser;Ursula Püntener

  • Unique carbohydrate–carbohydrate interactions are required for high affinity binding between FcγRIII and antibodies lacking core fucose

    Claudia Ferrara;Sandra Grau;Christiane Jäger;Peter Sondermann

  • Engineered glycoforms of an antineuroblastoma IgG1 with optimized antibody-dependent cellular cytotoxic activity

    Unknown

  • The Carbohydrate at FcγRIIIa Asn-162 AN ELEMENT REQUIRED FOR HIGH AFFINITY BINDING TO NON-FUCOSYLATED IgG GLYCOFORMS

    Unknown

  • Epitope interactions of monoclonal antibodies targeting CD20 and their relationship to functional properties

    Christian Klein;Alfred Lammens;Wolfgang Schäfer;Guy Georges

  • Novel human IgG1 and IgG4 Fc-engineered antibodies with completely abolished immune effector functions

    Tilman Schlothauer;Sylvia Herter;Claudia Ferrara Koller;Sandra Grau-Richards

  • Preclinical Activity of the Type II CD20 Antibody GA101 (Obinutuzumab) Compared with Rituximab and Ofatumumab In Vitro and in Xenograft Models

    Sylvia Herter;Frank Herting;Olaf Mundigl;Inja Waldhauer

  • Progression of Lung Cancer Is Associated with Increased Dysfunction of T Cells Defined by Coexpression of Multiple Inhibitory Receptors

    Daniela Stefanie Thommen;Jens Schreiner;Philipp Müller;Petra Herzig

  • Glofitamab, a Novel, Bivalent CD20-Targeting T-Cell-Engaging Bispecific Antibody, Induces Durable Complete Remissions in Relapsed or Refractory B-Cell Lymphoma: A Phase I Trial

    Martin Hutchings;Franck Morschhauser;Gloria Iacoboni;Carmelo Carlo-Stella

  • PD-1 combination therapy with IL-2 modifies CD8+ T cell exhaustion program

    Unknown

  • A Novel Carcinoembryonic Antigen T-Cell Bispecific Antibody (CEA TCB) for the Treatment of Solid Tumors.

    Marina Bacac;Tanja Fauti;Johannes Sam;Sara Colombetti

  • Dendritic cells dictate responses to PD-L1 blockade cancer immunotherapy.

    Maud Mayoux;Andreas Roller;Vesna Pulko;Stefano Sammicheli

  • Cergutuzumab amunaleukin (CEA-IL2v), a CEA-targeted IL-2 variant-based immunocytokine for combination cancer immunotherapy: Overcoming limitations of aldesleukin and conventional IL-2-based immunocytokines.

    Christian Klein;Inja Waldhauer;Valeria G. Nicolini;Anne Freimoser-Grundschober

  • Target Expression, Generation, Preclinical Activity, and Pharmacokinetics of the BCMA-T Cell Bispecific Antibody EM801 for Multiple Myeloma Treatment

    Anja Seckinger;Jose Antonio Delgado;Samuel Moser;Laura Moreno

  • PD-1-cis IL-2R agonism yields better effectors from stem-like CD8+ T cells

    Unknown

  • Modulation of therapeutic antibody effector functions by glycosylation engineering: Influence of Golgi enzyme localization domain and co‐expression of heterologous β1, 4‐<i>N</i>‐acetylglucosaminyltransferase III and Golgi α‐mannosidase II

    Unknown

  • Epitope characterization and crystal structure of GA101 provide insights into the molecular basis for type I/II distinction of CD20 antibodies.

    Gerhard Niederfellner;Alfred Lammens;Olaf Mundigl;Guy J. Georges

  • Tumor-targeted 4-1BB agonists for combination with T cell bispecific antibodies as off-the-shelf therapy.

    Christina Claus;Claudia Ferrara;Wei Xu;Johannes Sam

  • CD20-TCB with Obinutuzumab Pretreatment as Next-Generation Treatment of Hematologic Malignancies.

    Marina Bacac;Sara Colombetti;Sylvia Herter;Johannes Sam

  • Glycoengineering of Therapeutic Antibodies Enhances Monocyte/Macrophage-Mediated Phagocytosis and Cytotoxicity

    Sylvia Herter;Martina C. Birk;Christian Klein;Christian Gerdes

Frequent Co-Authors

Christian Klein
Christian Klein Roche (Switzerland)
Ulrich Brinkmann
Ulrich Brinkmann Roche (Switzerland)
Otto C. Boerman
Otto C. Boerman Radboud University
Sebastian Kobold
Sebastian Kobold Ludwig-Maximilians-Universität München
Laurence B. Peterson
Laurence B. Peterson Roche (Switzerland)
Karl-Peter Hopfner
Karl-Peter Hopfner Ludwig-Maximilians-Universität München
Marc Schmitz
Marc Schmitz TU Dresden
Alfred Zippelius
Alfred Zippelius University Hospital of Basel
Josep Tabernero
Josep Tabernero Vall d´Hebron Institute of Oncology
Walter F. Bodmer
Walter F. Bodmer University of Oxford

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