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D-Index & Metrics

Biology and Biochemistry

D-Index
60
Citations
15333
World Ranking
11817
National Ranking
428

Overview

Nadia Messaddeq is affiliated with the Institute of Genetics and Molecular and Cellular Biology in France. Their research spans multiple fields of study, primarily focusing on biochemistry, genetics, and molecular biology, with a significant contribution to medicine. The main areas of expertise include molecular biology, cell biology, genetics, cellular and molecular neuroscience, and materials chemistry.

Their research topics cover a diverse range of subjects related to genetic and cellular functions, including:

  • Genetic neurodegenerative diseases
  • Muscle physiology and disorders
  • Genetic syndromes and imprinting
  • Genetic and kidney cyst diseases
  • RNA research and splicing
  • Mitochondrial function and pathology
  • Cellular transport and secretion

Nadia Messaddeq has published extensively, with some notable papers including:

  • High Levels of Frataxin Overexpression Lead to Mitochondrial and Cardiac Toxicity in Mouse Models (2020) published in Molecular Therapy - Methods & Clinical Development
  • Hamster organotypic modeling of SARS-CoV-2 lung and brainstem infection (2021) published in Nature Communications
  • Androgen receptor coordinates muscle metabolic and contractile functions (2023) published in Journal of Cachexia Sarcopenia and Muscle
  • Mice with muscle-specific deletion of Bin1 recapitulate centronuclear myopathy and acute downregulation of dynamin 2 improves their phenotypes (2021) published in Molecular Therapy
  • Relative Adipose Tissue Failure in Alström Syndrome Drives Obesity-Induced Insulin Resistance (2020) published in Diabetes

The scientist commonly publishes in several venues including bioRxiv (Cold Spring Harbor Laboratory), Nature Communications, Diabetes, Proceedings of the National Academy of Sciences, and Molecular Therapy - Methods & Clinical Development, reflecting a strong presence in both preprint and peer-reviewed journals.

Nadia Messaddeq frequently collaborates with other researchers, with key co-authors including:

  • Jocelyn Laporte
  • Nicolas Anton
  • Thierry Vandamme
  • Daniel Metzger
  • Sidy Mouhamed Dieng

Best Publications

  • Bile acids induce energy expenditure by promoting intracellular thyroid hormone activation

    Mitsuhiro Watanabe;Sander M. Houten;Chikage Mataki;Marcelo A. Christoffolete

  • Absence of integrin alpha 6 leads to epidermolysis bullosa and neonatal death in mice.

    E Georges-Labouesse;N Messaddeq;G Yehia;L Cadalbert

  • Embryonic retinoic acid synthesis is essential for heart morphogenesis in the mouse.

    Karen Niederreither;Julien Vermot;Nadia Messaddeq;Brigitte Schuhbaur

  • Peroxisome proliferator-activated receptor γ is required in mature white and brown adipocytes for their survival in the mouse

    Takeshi Imai;Reiko Takakuwa;Sandra Marchand;Emilie Dentz

  • Skin abnormalities generated by temporally controlled RXRα mutations in mouse epidermis

    Mei Li;Arup Kumar Indra;Xavier Warot;Jacques Brocard

  • Essential role of α6 integrins in cortical and retinal lamination

    Elisabeth Georges-Labouesse;Manuel Mark;Nadia Messaddeq;Anne Gansmüller

  • Serotonin 2B receptor is required for heart development.

    Canan G. Nebigil;Doo Sup Choi;Andrée Dierich;Pierre Hickel

  • Oral-facial-digital type I protein is required for primary cilia formation and left-right axis specification.

    Maria Immacolata Ferrante;Alessandro Zullo;Adriano Barra;Sabrina Bimonte

  • Spatio-temporally controlled site-specific somatic mutagenesis in the mouse

    Jacques Brocard;Xavier Warot;Olivia Wendling;Nadia Messaddeq

  • Misregulated alternative splicing of BIN1 is associated with T tubule alterations and muscle weakness in myotonic dystrophy

    Charlotte Fugier;Arnaud F Klein;Caroline Hammer;Stéphane Vassilopoulos

  • RXR-alpha ablation in skin keratinocytes results in alopecia and epidermal alterations.

    Mei Li;Hideki Chiba;Xavier Warot;Nadia Messaddeq

  • Role of the retinoic acid receptor beta (RARbeta) during mouse development.

    N B Ghyselinck;V Dupe;A Dierich;N Messaddeq

  • Developmental expression pattern of Stra6, a retinoic acid-responsive gene encoding a new type of membrane protein.

    Philippe Bouillet;Vincent Sapin;Claire Chazaud;Nadia Messaddeq

  • Retinoid X receptor ablation in adult mouse keratinocytes generates an atopic dermatitis triggered by thymic stromal lymphopoietin

    Mei Li;Nadia Messaddeq;Marius Teletin;Jean-Louis Pasquali

  • 5-HT2B receptor-mediated serotonin morphogenetic functions in mouse cranial neural crest and myocardiac cells

    Doo Sup Choi;Simon J. Ward;Nadia Messaddeq;Jean Marie Launay

  • Liver receptor homolog 1 is essential for ovulation

    Rajesha Duggavathi;David Volle;Chikage Mataki;Maria Cristina Antal

  • Prevention and reversal of severe mitochondrial cardiomyopathy by gene therapy in a mouse model of Friedreich's ataxia

    Morgane Perdomini;Brahim Belbellaa;Laurent Monassier;Laurence Reutenauer

  • The lipid phosphatase myotubularin is essential for skeletal muscle maintenance but not for myogenesis in mice

    Anna Buj-Bello;Vincent Laugel;Nadia Messaddeq;Hala Zahreddine

  • Vitamin A deficiency and mutations of RXRalpha, RXRbeta and RARalpha lead to early differentiation of embryonic ventricular cardiomyocytes

    P. Kastner;N. Messaddeq;M. Mark;O. Wendling

  • Transient ciliogenesis involving Bardet-Biedl syndrome proteins is a fundamental characteristic of adipogenic differentiation

    Vincent Marion;Corinne Stoetzel;Dominique Schlicht;Nadia Messaddeq

Frequent Co-Authors

Pierre Chambon
Pierre Chambon Institute of Genetics and Molecular and Cellular Biology
Daniel Metzger
Daniel Metzger Institute of Genetics and Molecular and Cellular Biology
Thierry F. Vandamme
Thierry F. Vandamme University of Strasbourg
Manuel Mark
Manuel Mark Institute of Genetics and Molecular and Cellular Biology
Pascal Dollé
Pascal Dollé Institute of Genetics and Molecular and Cellular Biology
Norbert B. Ghyselinck
Norbert B. Ghyselinck Institute of Genetics and Molecular and Cellular Biology
Andrée Dierich
Andrée Dierich Institute of Genetics and Molecular and Cellular Biology
Luc Maroteaux
Luc Maroteaux Université Paris Cité
Jean-Louis Mandel
Jean-Louis Mandel Institute of Genetics and Molecular and Cellular Biology
Hélène Dollfus
Hélène Dollfus University of Strasbourg

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