World's Best Scientists 2026 revealed!

D-Index & Metrics

Genetics

D-Index
61
Citations
19389
World Ranking
3033
National Ranking
1324

Research.com Recognitions

  • 1999 - Potamkin Prize for Research in Pick's, Alzheimer's, and Related Diseases, American Academy of Neurology

Overview

Kirk C. Wilhelmsen is affiliated with the University of North Carolina at Chapel Hill in the United States. Their research spans multiple disciplines, primarily focusing on Biochemistry, Genetics, and Molecular Biology, as well as Medicine. Within these broader fields, Wilhelmsen's work covers specialized subfields including Molecular Biology, Genetics, Pediatrics, Perinatology and Child Health, Physiology, and Cognitive Neuroscience.

The scientist's research topics include Dementia and Cognitive Impairment Research, Genetic Associations and Epidemiology, Genomics and Rare Diseases, Alzheimer's disease research and treatments, Alcohol Consumption and Health Effects, Prenatal Screening and Diagnostics, and Single-cell and spatial transcriptomics.

Wilhelmsen has contributed papers to a variety of publication venues, with a notable number of works appearing in UNC Libraries. Other frequent venues include bioRxiv (Cold Spring Harbor Laboratory), Genetics in Medicine, Briefings in Bioinformatics, and Aging Neuropsychology and Cognition.

Among the recent papers authored or co-authored by Wilhelmsen are:

  • Ultrasound Blood-Brain Barrier Opening and Aducanumab in Alzheimer's Disease, 2024, New England Journal of Medicine
  • An approach to integrating exome sequencing for fetal structural anomalies into clinical practice, 2020, Genetics in Medicine
  • Focused ultrasound-mediated blood-brain barrier opening in Alzheimer's disease: long-term safety, imaging, and cognitive outcomes, 2022, Journal of neurosurgery
  • SMNN: batch effect correction for single-cell RNA-seq data via supervised mutual nearest neighbor detection, 2020, Briefings in Bioinformatics
  • Frontal and temporal lobe correlates of verbal learning and memory in aMCI and suspected Alzheimer's disease dementia, 2022, Aging Neuropsychology and Cognition

Collaboration has featured prominently in Wilhelmsen's career. Frequent co-authors include Cindy L. Ehlers, Ian R. Gizer, Jonathan S. Berg, Marc W. Haut, and Rashi I. Mehta.

Wilhelmsen was awarded the Potamkin Prize for Research in Pick's, Alzheimer's, and Related Diseases by the American Academy of Neurology in 1999.

Best Publications

  • Mutation-Specific Functional Impairments in Distinct Tau Isoforms of Hereditary FTDP-17

    Ming Hong;Victoria Zhukareva;Vanessa Vogelsberg-Ragaglia;Zbigniew Wszolek

  • Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease

    Rebecca Sims;Sven J. Van Der Lee;Adam C. Naj;Céline Bellenguez;Céline Bellenguez

  • Frontotemporal dementia and parkinsonism linked to chromosome 17: A consensus conference

    Norman L. Foster;Kirk C. Wilhelmsen;Anders A. F. Sima;Anders A. F. Sima;Margaret Z. Jones

  • Genetic mapping of chronic childhood-onset spinal muscular atrophy to chromosome 5q1 1.2–13.3

    L. M. Brzustowicz;L. M. Brzustowicz;T. Lehner;T. Lehner;L. H. Castilla;L. H. Castilla;G. K. Penchaszadeh;G. K. Penchaszadeh

  • Pathogenic implications of mutations in the tau gene in pallido-ponto-nigral degeneration and related neurodegenerative disorders linked to chromosome 17

    Lorraine N. Clark;Parvoneh Poorkaj;Zbigniew Wszolek;Daniel H. Geschwind

  • Localization of disinhibition-dementia-parkinsonism-amyotrophy complex to 17q21-22

    K. C. Wilhelmsen;T. Lynch;E. Pavlou;M. Higgins

  • Exceptionally low likelihood of Alzheimer’s dementia in APOE2 homozygotes from a 5,000-person neuropathological study

    Eric M Reiman;Joseph F Arboleda-Velasquez;Yakeel T Quiroz;Matthew J Huentelman

  • Localization of a gene for partial epilepsy to chromosome 10q

    Ruth Ottman;Ruth Ottman;Neil Risch;W. Allen Hauser;Timothy A. Pedley

  • Clinical characteristics of a family with chromosome 17‐linked disinhibition‐dementia‐ parkinsonism‐amyotrophy complex

    T. Lynch;M. Sano;K. S. Marder;K. L. Bell

  • Loss of kindlin-1, a human homolog of the Caenorhabditis elegans actin-extracellular-matrix linker protein UNC-112, causes Kindler syndrome

    Dawn H. Siegel;Gabrielle H.S. Ashton;Homero G. Penagos;James V. Lee

  • Nucleic acid sequences of the oncogene v-rel in reticuloendotheliosis virus strain T and its cellular homolog, the proto-oncogene c-rel.

    K C Wilhelmsen;K Eggleton;H M Temin

  • A novel Alzheimer disease locus located near the gene encoding tau protein

    G. Jun;C. A. Ibrahim-Verbaas;M. Vronskaya;J-C Lambert;J-C Lambert;J-C Lambert

  • Linkage mapping of dopa–responsive dystonia (DRD) to chromosome 14q

    T G Nygaard;K C Wilhelmsen;N J Risch;D L Brown

  • Novel Alzheimer Disease Risk Loci and Pathways in African American Individuals Using the African Genome Resources Panel: A Meta-analysis

    Brian W. Kunkle;Michael Schmidt;Hans Ulrich Klein;Adam C. Naj

  • TAU GENE MUTATION IN FAMILIAL PROGRESSIVE SUBCORTICAL GLIOSIS

    M. Goedert;M. G. Spillantini;R. A. Crowther;S. G. Chen

  • Mapping of familial primary pulmonary hypertension locus (pph1) to chromosome 2q31-q32

    J. H. Morse;A. C. Jones;R. J. Barst;S. E. Hodge

  • Dissecting the Causal Mechanism of X-Linked Dystonia-Parkinsonism by Integrating Genome and Transcriptome Assembly

    Tatsiana Aneichyk;Tatsiana Aneichyk;William T. Hendriks;Rachita Yadav;Rachita Yadav;David Shin

  • Association of a single nucleotide polymorphism in neuronal acetylcholine receptor subunit alpha 5 (CHRNA5) with smoking status and with 'pleasurable buzz' during early experimentation with smoking

    Richard Sherva;Kirk Wilhelmsen;Cynthia S. Pomerleau;Scott A. Chasse

  • The virus-specific intracellular RNA species of two murine coronaviruses: MHV-A59 and MHV-JHM

    Julian L. Leibowitz;Kirk C. Wilhelmsen;Clifford W. Bond

  • Pathogenic implications of mutations in the tau gene in pallido-ponto-nigral degeneration and related neurodegenerative disorders linked to chromosome 17 (frontotemporal dementia and Parkinsonismytauopathiesyglial and neuronal tanglesymicrotubule associated proteinsyAlzheimer's disease)

    Lorraine N. Clark;D Aniel H. Geschwind;Ziad S. Nasreddine;D Iane Li

Frequent Co-Authors

Cindy L. Ehlers
Cindy L. Ehlers Scripps Research Institute
Jonathan S. Berg
Jonathan S. Berg University of North Carolina at Chapel Hill
Bruce L. Miller
Bruce L. Miller University of California, San Francisco
Bruce M. Psaty
Bruce M. Psaty University of Washington
Alexander P. Reiner
Alexander P. Reiner University of Washington
Rachelle S. Doody
Rachelle S. Doody Roche (Switzerland)
Ramon Diaz-Arrastia
Ramon Diaz-Arrastia University of Pennsylvania
Daniel H. Geschwind
Daniel H. Geschwind University of California, Los Angeles
Yun Li
Yun Li University of North Carolina at Chapel Hill
Marc A. Schuckit
Marc A. Schuckit University of California, San Diego

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