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Medicine

D-Index
140
Citations
87988
World Ranking
1672
National Ranking
967

Overview

Kenneth Aldape is affiliated with the National Institutes of Health in the United States. Their research spans fields primarily within medicine, with significant contributions to biochemistry, genetics, and molecular biology. Aldape's work bridges multiple subfields including genetics, molecular biology, cancer research, pulmonary and respiratory medicine, and neurology.

The scientist has a substantial publication record in topics related to glioma diagnosis and treatment, cancer genomics and diagnostics, management of meningioma and schwannoma, epigenetics and DNA methylation, brain metastases and treatment, radiomics and machine learning in medical imaging, as well as neuroblastoma research and treatments.

Frequent publication venues for Aldape include:

  • Neuro-Oncology
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Cancer Research
  • Neuro-Oncology Advances
  • Acta Neuropathologica

Some of the recent papers associated with Aldape's research include:

  • "The repertoire of mutational signatures in human cancer," 2020, published in Nature
  • "Pan-cancer analysis of whole genomes," 2020, published in Nature
  • "Glioblastoma in adults: a Society for Neuro-Oncology (SNO) and European Society of Neuro-Oncology (EANO) consensus review on current management and future directions," 2020, published in Neuro-Oncology
  • "Comprehensive analysis of chromothripsis in 2,658 human cancers using whole-genome sequencing," 2020, published in Nature Genetics
  • "cIMPACT-NOW update 6: new entity and diagnostic principle recommendations of the cIMPACT-Utrecht meeting on future CNS tumor classification and grading," 2020, published in Brain Pathology

Regularly collaborating with a range of researchers, Aldape's frequent co-authors include Zied Abdullaev, Gelareh Zadeh, Farshad Nassiri, Martha Quezado, and Mark R. Gilbert. These collaborations contribute to a robust interdisciplinary network within oncology and molecular research fields.

Best Publications

  • Comprehensive genomic characterization defines human glioblastoma genes and core pathways

    Roger McLendon;Allan Friedman;Darrell Bigner;Erwin G. Van Meir

  • The Somatic Genomic Landscape of Glioblastoma

    Cameron W. Brennan;Roel G W Verhaak;Aaron McKenna;Benito Campos

  • Comprehensive molecular characterization of urothelial bladder carcinoma

    John N Weinstein;Rehan Akbani;Bradley McIntosh Broom;Wenyi Wang

  • Molecular subclasses of high-grade glioma predict prognosis, delineate a pattern of disease progression, and resemble stages in neurogenesis

    Heidi S. Phillips;Samir Kharbanda;Ruihuan Chen;William F. Forrest

  • Comprehensive, Integrative Genomic Analysis of Diffuse Lower-Grade Gliomas.

    Daniel J. Brat;Roel G.W. Verhaak;Kenneth D. Aldape;W. K.Alfred Yung

  • Pan-cancer analysis of whole genomes

    Peter J. Campbell;Gad Getz;Jan O. Korbel;Joshua M. Stuart

  • DNA methylation-based classification of central nervous system tumours

    David Capper;David Capper;David Capper;David T. W. Jones;Martin Sill;Volker Hovestadt

  • A Randomized Trial of Bevacizumab for Newly Diagnosed Glioblastoma

    Mark R. Gilbert;James J. Dignam;Terri S. Armstrong;Terri S. Armstrong;Jeffrey Scott Wefel

  • Identification of a CpG island methylator phenotype that defines a distinct subgroup of glioma.

    Houtan Noushmehr;Daniel J. Weisenberger;Kristin Diefes;Heidi S. Phillips

  • Hotspot mutations in H3F3A and IDH1 define distinct epigenetic and biological subgroups of glioblastoma.

    Dominik Sturm;Hendrik Witt;Hendrik Witt;Volker Hovestadt;Dong Anh Khuong-Quang

  • Molecular Profiling Reveals Biologically Discrete Subsets and Pathways of Progression in Diffuse Glioma.

    Michele Ceccarelli;Floris P Barthel;Tathiane M Malta;Thais S Sabedot

  • The transcriptional network for mesenchymal transformation of brain tumours

    Maria Stella Carro;Wei Keat Lim;Mariano Javier Alvarez;Robert J. Bollo

  • Nitric oxide synthase complexed with dystrophin and absent from skeletal muscle sarcolemma in Duchenne muscular dystrophy.

    Jay E. Brenman;Daniel S. Chao;Houhui Xia;Kenneth D Aldape

  • Epidemiology and molecular pathology of glioma.

    Judith A Schwartzbaum;James L Fisher;Kenneth D Aldape;Margaret Wrensch

  • Cilengitide combined with standard treatment for patients with newly diagnosed glioblastoma with methylated MGMT promoter (CENTRIC EORTC 26071-22072 study): a multicentre, randomised, open-label, phase 3 trial

    Roger Stupp;Roger Stupp;Monika E Hegi;Thierry Gorlia;Sara C Erridge

  • Microenvironment-induced PTEN loss by exosomal microRNA primes brain metastasis outgrowth

    Lin Zhang;Siyuan Zhang;Siyuan Zhang;Jun Yao;Frank J. Lowery

  • Molecular Classification of Ependymal Tumors across All CNS Compartments, Histopathological Grades, and Age Groups

    Kristian W. Pajtler;Kristian W. Pajtler;Hendrik Witt;Martin Sill;David T.W. Jones

  • Mesenchymal Differentiation Mediated by NF-κB Promotes Radiation Resistance in Glioblastoma

    Krishna P.L. Bhat;Veerakumar Balasubramaniyan;Brian Vaillant;Ravesanker Ezhilarasan

  • Nuclear PKM2 regulates β-catenin transactivation upon EGFR activation

    Weiwei Yang;Yan Xia;Haitao Ji;Yanhua Zheng

  • The somatic genomic landscape of glioblastoma

    Cameron W. Brennan;Roel G. W. Verhaak;Aaron Mckenna;Benito Campos

Frequent Co-Authors

Andreas von Deimling
Andreas von Deimling Heidelberg University
Stefan M. Pfister
Stefan M. Pfister German Cancer Research Center
Felix Sahm
Felix Sahm University Hospital Heidelberg
Pieter Wesseling
Pieter Wesseling University of Amsterdam
Mark R. Gilbert
Mark R. Gilbert National Institutes of Health
Wolfgang Wick
Wolfgang Wick German Cancer Research Center
Guido Reifenberger
Guido Reifenberger Heinrich Heine University Düsseldorf
Michael D. Prados
Michael D. Prados University of California, San Francisco
Minesh P. Mehta
Minesh P. Mehta University of Maryland, Baltimore
Michael A. Vogelbaum
Michael A. Vogelbaum Cleveland Clinic

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