World's Best Scientists 2026 revealed!

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Molecular Biology

D-Index
62
Citations
13461
World Ranking
1853
National Ranking
925

Overview

Jurrien Dean is affiliated with the National Institutes of Health in the United States. Their research primarily spans the fields of biochemistry, genetics, molecular biology, and medicine. Within these broad domains, their work has focused extensively on molecular biology, public health, environmental and occupational health, reproductive medicine, plant science, and immunology.

The scientist's research is centered around key topics such as reproductive biology and fertility, RNA research and splicing, sperm and testicular function, renal and related cancers, chromosomal and genetic variations, epigenetics and DNA methylation, and CRISPR and genetic engineering.

Jurrien Dean has contributed to multiple scientific papers, including:

  • "FIGLA, LHX8 and SOHLH1 transcription factor networks regulate mouse oocyte growth and differentiation" (2020) published in Nucleic Acids Research
  • "Sperm acrosome overgrowth and infertility in mice lacking chromosome 18 pachytene piRNA" (2021) published in PLoS Genetics
  • "EXOSC10 sculpts the transcriptome during the growth-to-maturation transition in mouse oocytes" (2020) published in Nucleic Acids Research
  • "Degradation and translation of maternal mRNA for embryogenesis" (2024) published in Trends in Genetics
  • "Evolution of the Collaborative Pediatric Critical Care Research Network" (2022) published in Pediatric Critical Care Medicine

Frequent collaborators in their research include Di Wu, Qiliang Xin, Zhengpin Wang, Guanghui Yang, and Iris Feng.

Jurrien Dean has published prominently in several scientific venues, with the highest number of publications in bioRxiv (Cold Spring Harbor Laboratory), followed by Nucleic Acids Research, Pediatric Critical Care Medicine, Cell Reports, and Development.

In addition to journal articles, they have authored a book titled UT Extension Personnel Directory, 1910 - 2020, published by Newfound Press, the University of Tennessee Libraries eBooks, in 2021.

Best Publications

  • Mater, a maternal effect gene required for early embryonic development in mice.

    Zhi-Bin Tong;Lyn Gold;Karl E. Pfeifer;Heidi Dorward

  • FIGalpha, a germ cell-specific transcription factor required for ovarian follicle formation

    Selma M. Soyal;Asma Amleh;Jurrien Dean

  • Maternal control of early mouse development

    Lei Li;Ping Zheng;Jurrien Dean

  • Expression of Cre recombinase in mouse oocytes: A means to study maternal effect genes

    Wilhelmine N. de Vries;Lorraine T. Binns;Karen S. Fancher;Jurrien Dean

  • Mice homozygous for an insertional mutation in the Zp3 gene lack a zona pellucida and are infertile

    Tracy Rankin;Mary Familari;Eric Lee;Ann Ginsberg

  • A subcortical maternal complex essential for preimplantation mouse embryogenesis.

    Lei Li;Boris Baibakov;Jurrien Dean

  • Defective zonae pellucidae in Zp2-null mice disrupt folliculogenesis, fertility and development.

    T.L. Rankin;M. O'Brien;E. Lee;K. Wigglesworth

  • Ovastacin, a cortical granule protease, cleaves ZP2 in the zona pellucida to prevent polyspermy

    Anna D. Burkart;Bo Xiong;Boris Baibakov;Maria Jiménez-Movilla

  • Coordinate expression of the three zona pellucida genes during mouse oogenesis.

    Olga Epifano;Li-fang Liang;Mary Familari;Malcolm C. Moos

  • FIGALPHA , A GERM CELL SPECIFIC TRANSCRIPTION FACTOR INVOLVED IN THE COORDINATE EXPRESSION OF THE ZONA PELLUCIDA GENES

    Li Fang Liang;Selma M. Soyal;Jurrien Dean

  • Abnormal zonae pellucidae in mice lacking ZP1 result in early embryonic loss.

    Tracy Rankin;Prue Talbot;Eric Lee;Jurrien Dean

  • Sickle-cell anemia: molecular and cellular bases of therapeutic approaches (first of three parts).

    Jurrien Dean;Alan N. Schechter

  • Autoimmune disease of the ovary induced by a ZP3 peptide from the mouse zona pellucida

    Sung Hee Rhim;Sarah E. Millar;Frank Robey;An Ming Luo

  • The maternal to zygotic transition in mammals.

    Lei Li;Xukun Lu;Jurrien Dean

  • Vaccination with a synthetic zona pellucida peptide produces long-term contraception in female mice

    Sarah E. Millar;Steven M. Chamow;Anne W. Baur;Constance Oliver

  • Human homolog of the mouse sperm receptor

    Margaret E. Chamberlin;Jurrien Dean

  • Human ZP3 restores fertility in Zp3 null mice without affecting order-specific sperm binding

    Tracy L. Rankin;Zhi Bin Tong;Philip E. Castle;Eric Lee

  • Molecular analysis of cDNA coding for ZP3, a sperm binding protein of the mouse zona pellucida.

    Maurice J. Ringuette;Margaret E. Chamberlin;Anne W. Baur;Donna A. Sobieski

  • Role of Filia, a maternal effect gene, in maintaining euploidy during cleavage-stage mouse embryogenesis

    Ping Zheng;Jurrien Dean

  • Oocyte-specific expression and developmental regulation of ZP3, the sperm receptor of the mouse zona pellucida.

    Caroline C. Philpott;Maurice J. Ringuette;Jurrien Dean

Frequent Co-Authors

Sarah E. Millar
Sarah E. Millar University of Pennsylvania
Kenneth S. K. Tung
Kenneth S. K. Tung University of Virginia
Rolf Kemler
Rolf Kemler Max Planck Society
Barbara B. Knowles
Barbara B. Knowles Jackson Laboratory
Henry M. Fales
Henry M. Fales National Institutes of Health
Dragan Maric
Dragan Maric National Institutes of Health
William S. Modi
William S. Modi CUUR Diagnostics
Neal G. Copeland
Neal G. Copeland The University of Texas MD Anderson Cancer Center
Nancy A. Jenkins
Nancy A. Jenkins The University of Texas MD Anderson Cancer Center
Robert B. Moore
Robert B. Moore Virginia Tech

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