Julie A. DeMartino

Best Publications

• Impaired neuropathic pain responses in mice lacking the chemokine receptor CCR2

  Catherine Abbadie;Jill A. Lindia;Anne Marie Cumiskey;Larry B. Peterson

  876
  Citations

• Cloning, expression, and characterization of the human eosinophil eotaxin receptor.

  Unknown

  554
  Citations

• Two-site binding of C5a by its receptor: An alternative binding paradigm for G protein-coupled receptors

  S J Siciliano;T E Rollins;J DeMartino;Z Konteatis

  334
  Citations

• A single amino acid substitution in a common African allele of the CD4 molecule ablates binding of the monoclonal antibody, OKT4.

  Seth Lederman;Julie A. DeMartino;Bruce L. Daugherty;Ivan Foeldvari

  329
  Citations

• Polymerase chain reaction facilitates the cloning, CDR-grafting, and rapid expression of a murine monoclonal antibody directed against the CD18 component of leukocyte integrins.

  Unknown

  313
  Citations

• Antibody-mediated blockade of the CXCR3 chemokine receptor results in diminished recruitment of T helper 1 cells into sites of inflammation.

  Jenny H. Xie;Naomi Nomura;Min Lu;Shiow-Ling Chen

  239
  Citations

• CCR5, CXCR4, and CD4 Are Clustered and Closely Apposed on Microvilli of Human Macrophages and T Cells

  Irwin I. Singer;Solomon Scott;Douglas W. Kawka;Jayne Chin

  231
  Citations

• Binding and Functional Properties of Recombinant and Endogenous CXCR3 Chemokine Receptors

  Unknown

  215
  Citations

• Severe Disease, Unaltered Leukocyte Migration, and Reduced IFN-γ Production in CXCR3−/− Mice with Experimental Autoimmune Encephalomyelitis

  LiPing Liu;DeRen Huang;Masaru Matsui;Toby T. He

  209
  Citations

• The CXC Chemokine Murine Monokine Induced by IFN-γ (CXC Chemokine Ligand 9) Is Made by APCs, Targets Lymphocytes Including Activated B Cells, and Supports Antibody Responses to a Bacterial Pathogen In Vivo

  Matthew K. Park;Doron Amichay;Paul Love;Elizabeth Wick

  201
  Citations

• Use of a small molecule CCR5 inhibitor in macaques to treat simian immunodeficiency virus infection or prevent simian-human immunodeficiency virus infection.

  Ronald S. Veazey;Per Johan Klasse;Thomas J. Ketas;Jacqueline D. Reeves

  186
  Citations

• Potent 1,3,4-trisubstituted pyrrolidine CCR5 receptor antagonists: effects of fused heterocycles on antiviral activity and pharmacokinetic properties.

  Dooseop Kim;Liping Wang;Jeffrey J. Hale;Christopher L. Lynch

  179
  Citations

• Mice overexpressing chemokine ligand 2 (CCL2) in astrocytes display enhanced nociceptive responses.

  J. Menetski;S. Mistry;M. Lu;J.S. Mudgett

  165
  Citations

• RN486, a Selective Bruton's Tyrosine Kinase Inhibitor, Abrogates Immune Hypersensitivity Responses and Arthritis in Rodents

  Daigen Xu;Yong Kim;Jennifer Postelnek;Minh Diem Vu

  163
  Citations

• The amino terminus of the human C5a receptor is required for high affinity C5a binding and for receptor activation by C5a but not C5a analogs.

  J A DeMartino;G Van Riper;S J Siciliano;C J Molineaux

  161
  Citations

• Antagonists of the human CCR5 receptor as anti-HIV-1 agents. Part 4: synthesis and structure–Activity relationships for 1-[N-(Methyl)-N-(phenylsulfonyl)amino]-2-(phenyl)-4-(4-(N-(alkyl)-N-(benzyloxycarbonyl)amino)piperidin-1-yl)butanes

  Paul E. Finke;Bryan Oates;Sander G. Mills;Malcolm MacCoss

  140
  Citations

• Antagonists of the human CCR5 receptor as anti-HIV-1 agents. Part 1: Discovery and initial structure–activity relationships for 1-amino-2-phenyl-4-(piperidin-1-yl)butanes

  Conrad P. Dorn;Paul E. Finke;Bryan Oates;Richard J. Budhu

  128
  Citations

• A Critical Site in the Core of the CCR5 Chemokine Receptor Required for Binding and Infectivity of Human Immunodeficiency Virus Type 1

  Salvatore J. Siciliano;Shawn E. Kuhmann;Youmin Weng;Navid Madani

  128
  Citations

• Binding of 2-aryl-4-(piperidin-1-yl)butanamines and 1,3,4-trisubstituted pyrrolidines to human CCR5: a molecular modeling-guided mutagenesis study of the binding pocket.

  Castonguay La;Weng Y;Adolfsen W;Di Salvo J

  119
  Citations

• The Amino Terminus of Human CCR5 Is Required for Its Function as a Receptor for Diverse Human and Simian Immunodeficiency Virus Envelope Glycoproteins

  C M Hill;D Kwon;M Jones;C B Davis

  109
  Citations