World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
61
Citations
12672
World Ranking
11393
National Ranking
4927

Overview

Jonathan R. Keller is affiliated with the National Cancer Institute in the United States. Their research primarily spans the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with a strong focus on Hematology, Genetics, and Molecular Biology. Additional subfields of study include Oncology and Cognitive Neuroscience.

Their work concentrates on several key topics including Hematopoietic Stem Cell Transplantation, Acute Myeloid Leukemia Research, Genetics and Neurodevelopmental Disorders, Mesenchymal Stem Cell Research, Myeloproliferative Neoplasms: Diagnosis and Treatment, Autism Spectrum Disorder Research, and Genomic Variations and Chromosomal Abnormalities.

Jonathan R. Keller has published in a number of scientific journals, with frequent contributions to:

  • Nature Communications
  • Current Opinion in Hematology
  • Journal of Clinical Investigation
  • Cell Reports
  • PLoS ONE

Their recent papers include:

  • "Pogz deficiency leads to transcription dysregulation and impaired cerebellar activity underlying autism-like behavior in mice," 2020, Nature Communications
  • "Protection of hematopoietic stem cells from stress-induced exhaustion and aging," 2020, Current Opinion in Hematology
  • "Id1 and Id3 Maintain Steady-State Hematopoiesis by Promoting Sinusoidal Endothelial Cell Survival and Regeneration," 2020, Cell Reports
  • "BRCA2-DSS1 interaction is dispensable for RAD51 recruitment at replication-induced and meiotic DNA double strand breaks," 2022, Nature Communications
  • "ID2 and HIF-1α collaborate to protect quiescent hematopoietic stem cells from activation, differentiation, and exhaustion," 2022, Journal of Clinical Investigation

Frequent co-authors of Jonathan R. Keller include:

  • Kristbjorn O. Gudmundsson
  • Brad L. Jakubison
  • Shweta Singh
  • Kimberly D. Klarmann
  • Holly M. Morris

Best Publications

  • Biologic properties of homogeneous interleukin 3. I. Demonstration of WEHI-3 growth factor activity, mast cell growth factor activity, p cell-stimulating factor activity, colony-stimulating factor activity, and histamine-producing cell-stimulating factor activity.

    J N Ihle;J Keller;S Oroszlan;L E Henderson

  • Characterization and regulation of RB6-8C5 antigen expression on murine bone marrow cells.

    K Hestdal;F W Ruscetti;J N Ihle;S E Jacobsen

  • Procedures for the purification of interleukin 3 to homogeneity.

    J N Ihle;J Keller;L Henderson;F Klein

  • Bcl11a is essential for normal lymphoid development

    Pentao Liu;Jonathan R Keller;Mariaestela Ortiz;Lino Tessarollo

  • Eradication of Tumors through Simultaneous Ablation of CD276/B7-H3-Positive Tumor Cells and Tumor Vasculature

    Steven Seaman;Zhongyu Zhu;Saurabh Saha;Xiaoyan M. Zhang

  • Ganciclovir Treatment of Herpes Simplex Thymidine Kinase-Transduced Primary T Lymphocytes: An Approach for Specific In Vivo Donor T-cell Depletion After Bone Marrow Transplantation?

    P Tiberghien;CW Reynolds;J Keller;S Spence

  • Transforming growth factor beta is a potent inhibitor of interleukin 1 (IL-1) receptor expression: proposed mechanism of inhibition of IL-1 action.

    C M Dubois;F W Ruscetti;E W Palaszynski;L A Falk

  • Transforming growth factor beta 1 selectively regulates early murine hematopoietic progenitors and inhibits the growth of IL-3-dependent myeloid leukemia cell lines.

    J R Keller;C Mantel;G K Sing;L R Ellingsworth

  • Transforming growth factor beta selectively inhibits normal and leukemic human bone marrow cell growth in vitro.

    Garwin K. Sing;Jonathan R. Keller;Larry R. Ellingsworth;Francis W. Ruscetti

  • Transforming growth factor beta directly regulates primitive murine hematopoietic cell proliferation

    Jonathan R. Keller;Ian K. Mcniece;Kathleen T. Sill;Larry R. Ellingsworth

  • Transcriptome analysis of mouse stem cells and early embryos.

    Alexei A Sharov;Yulan Piao;Ryo Matoba;Dawood B Dudekula

  • Combined Loss of Cdk2 and Cdk4 Results in Embryonic Lethality and Rb Hypophosphorylation

    Cyril Berthet;Kimberly D. Klarmann;Mary Beth Hilton;Hyung Chan Suh

  • Interleukin 3: Possible Roles in the Regulation of Lymphocyte Differentiation and Growth

    James N. Ihle;Linda Rebar;Jonathan Keller;John C. Lee

  • Targeting IRAK1 as a Therapeutic Approach for Myelodysplastic Syndrome

    Garrett W. Rhyasen;Lyndsey Bolanos;Lyndsey Bolanos;Jing Fang;Andres Jerez

  • Phenotypic characteristics of cell lines requiring interleukin 3 for growth.

    J N Ihle;J Keller;J S Greenberger;L Henderson

  • Steel factor (c-kit ligand) promotes the survival of hematopoietic stem/progenitor cells in the absence of cell division.

    Jonathan R. Keller;Mariaestela Ortiz;Francis W. Ruscetti

  • The interferon-inducible p200 family of proteins: a perspective on their roles in cell cycle regulation and differentiation.

    Benyam Asefa;Kimberly D Klarmann;Neal G Copeland;Debra J Gilbert

  • Distinct Regions of the Interleukin-7 Receptor Regulate Different Bcl2 Family Members

    Qiong Jiang;Wen Qing Li;Robert R. Hofmeister;Howard A. Young

  • Stimulation of granulopoiesis by transforming growth factor beta: synergy with granulocyte/macrophage-colony-stimulating factor.

    Jonathan R. Keller;Sten E. W. Jacobsen;Kathleen T. Sill;Larry R. Ellingsworth

  • Bidirectional effects of transforming growth factor beta (TGF-beta) on colony-stimulating factor-induced human myelopoiesis in vitro: differential effects of distinct TGF-beta isoforms.

    Sten E.W. Jacobsen;Jonathan R. Keller;Francis W. Ruscetti;Paturu Kondaiah

Frequent Co-Authors

Francis W. Ruscetti
Francis W. Ruscetti National Institutes of Health
Sten Eirik W. Jacobsen
Sten Eirik W. Jacobsen University of Oxford
Dan L. Longo
Dan L. Longo Harvard University
Lino Tessarollo
Lino Tessarollo National Institutes of Health
Robert H. Wiltrout
Robert H. Wiltrout National Institutes of Health
James N. Ihle
James N. Ihle St. Jude Children's Research Hospital
William J. Murphy
William J. Murphy Texas A&M University
Scott K. Durum
Scott K. Durum National Institutes of Health
Joost J. Oppenheim
Joost J. Oppenheim National Institutes of Health
Howard A. Young
Howard A. Young National Institutes of Health

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