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Åsa K. Hedman

Åsa K. Hedman

D-Index & Metrics

Molecular Biology

D-Index
43
Citations
26070
World Ranking
2941
National Ranking
40

Overview

Åsa K. Hedman is a researcher affiliated with Pfizer (Sweden) in Sweden. Their research spans multiple areas primarily within biochemistry, genetics, and molecular biology, with a focus on medicine.

The main fields of study for Hedman include:

  • Biochemistry, Genetics and Molecular Biology
  • Medicine

The subfields of study reflect a specialization in:

  • Genetics
  • Molecular Biology
  • Cardiology and Cardiovascular Medicine
  • Immunology
  • Cancer Research

Hedman's research topics address several key areas:

  • Genetic Associations and Epidemiology
  • Epigenetics and DNA Methylation
  • RNA modifications and cancer
  • Cardiovascular Function and Risk Factors
  • Bioinformatics and Genomic Networks
  • Genomics and Rare Diseases
  • RNA Research and Splicing

Selected recent publications illustrate the scope and impact of their work:

  • "FinnGen provides genetic insights from a well-phenotyped isolated population," 2023, Nature
  • "Plasma proteomic associations with genetics and health in the UK Biobank," 2023, Nature
  • "Genome-wide association and Mendelian randomisation analysis provide insights into the pathogenesis of heart failure," 2020, Nature Communications
  • "Genomic and drug target evaluation of 90 cardiovascular proteins in 30,931 individuals," 2020, Nature Metabolism
  • "Genetics of circulating inflammatory proteins identifies drivers of immune-mediated disease risk and therapeutic targets," 2023, Nature Immunology

Frequent collaboration is evidenced by coauthors with whom Hedman has published extensively. The most frequent coauthors include:

  • Anders Mälarstig
  • Antti Hakanen
  • Adriana Huertas-Vázquez
  • Zhihao Ding
  • Margaret G. Ehm

Their publications have appeared in a variety of scientific venues, with a concentration in:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Communications
  • UNC Libraries
  • Nature
  • Nature Immunology

Overall, the profile of Åsa K. Hedman shows a continuous engagement in research related to human genetics, proteomics, cardiovascular and immune-mediated diseases, contributing to understanding genetic epidemiology and molecular mechanisms within these fields.

Best Publications

  • Genetic studies of body mass index yield new insights for obesity biology

    Adam E. Locke;Bratati Kahali;Sonja I. Berndt;Anne E. Justice

  • Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility.

    Anubha Mahajan;Min Jin Go;Weihua Zhang;Jennifer E. Below

  • Mapping cis - and trans -regulatory effects across multiple tissues in twins

    E Grundberg;K S Small;K S Small;Å K Hedman;A C Nica

  • Genome-wide association and Mendelian randomisation analysis provide insights into the pathogenesis of heart failure.

    S Shah;A Henry;C Roselli;H Lin

  • Epigenome-Wide Scans Identify Differentially Methylated Regions for Age and Age-Related Phenotypes in a Healthy Ageing Population

    Jordana T. Bell;Pei-Chien Tsai;Tsun-Po Yang;Ruth Pidsley

  • Meta-analysis of genome-wide association studies identifies eight new loci for type 2 diabetes in east Asians

    Yoon Shin Cho;Chien Hsiun Chen;Chien Hsiun Chen;Cheng Hu;Jirong Long

  • Genome-wide association study in individuals of South Asian ancestry identifies six new type 2 diabetes susceptibility loci

    Jaspal S Kooner;Danish Saleheen;Xueling Sim;Joban Sehmi;Joban Sehmi

  • The architecture of gene regulatory variation across multiple human tissues: the MuTHER study

    Alexandra C. Nica;Alexandra C. Nica;Leopold Parts;Daniel Glass;James Nisbet

  • Genomic and drug target evaluation of 90 cardiovascular proteins in 30,931 individuals

    Lasse Folkersen;Stefan Gustafsson;Qin Wang;Qin Wang;Daniel Hvidberg Hansen

  • Global Analysis of DNA Methylation Variation in Adipose Tissue from Twins Reveals Links to Disease-Associated Variants in Distal Regulatory Elements

    Elin Grundberg;Elin Grundberg;Eshwar Meduri;Eshwar Meduri;Johanna K. Sandling;Johanna K. Sandling;Johanna K. Sandling;Asa K. Hedman

  • Identification of an imprinted master trans regulator at the KLF14 locus related to multiple metabolic phenotypes

    Kerrin S. Small;Asa K. Hedman;Elin Grundberg;Alexandra C. Nica

  • A DNA methylation biomarker of alcohol consumption.

    C Liu;R E Marioni;R E Marioni;Åsa K Hedman;L Pfeiffer

  • Epigenome-wide Association Study (EWAS) of BMI, BMI Change, and Waist Circumference in African American Adults Identifies Multiple Replicated Loci

    Ellen W. Demerath;Weihua Guan;Megan L. Grove;Stella Aslibekyan

  • Gene expression changes with age in skin, adipose tissue, blood and brain.

    Daniel Glass;Daniel Glass;Ana Viñuela;Matthew N Davies;Adaikalavan Ramasamy

  • Association of Body Mass Index with DNA Methylation and Gene Expression in Blood Cells and Relations to Cardiometabolic Disease: A Mendelian Randomization Approach

    Michael M Mendelson;Michael M Mendelson;Michael M Mendelson;Riccardo E. Marioni;Riccardo E. Marioni;Roby Joehanes;Roby Joehanes;Chunyu Liu;Chunyu Liu

  • New loci for body fat percentage reveal link between adiposity and cardiometabolic disease risk

    Yingchang Lu;Felix R Day;Stefan Gustafsson;Stefan Gustafsson;Martin L Buchkovich

  • Large-scale metabolomic profiling identifies novel biomarkers for incident coronary heart disease.

    Andrea Ganna;Samira Salihovic;Johan Sundström;Corey D. Broeckling

  • DNA methylation of lipid-related genes affects blood lipid levels

    Liliane Pfeiffer;Simone Wahl;Luke C. Pilling;Eva Reischl

  • Genome-wide meta-analysis uncovers novel loci influencing circulating leptin levels

    Tuomas O Kilpeläinen;Tuomas O Kilpeläinen;Tuomas O Kilpeläinen;Jayne F Martin Carli;Alicja A Skowronski;Qi Sun;Qi Sun

  • Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility

    Anubha Mahajan;Min Jin Go;Weihua Zhang;Jennifer E. Below

Frequent Co-Authors

Cecilia M. Lindgren
Cecilia M. Lindgren University of Oxford
Erik Ingelsson
Erik Ingelsson Stanford University
Elin Grundberg
Elin Grundberg Children's Mercy Hospital
Tim D. Spector
Tim D. Spector King's College London
Panos Deloukas
Panos Deloukas Queen Mary University of London
Kerrin S. Small
Kerrin S. Small King's College London
Andrew P. Morris
Andrew P. Morris University of Liverpool
André G. Uitterlinden
André G. Uitterlinden Erasmus University Rotterdam
Lars Lind
Lars Lind Uppsala University

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