John Kay

Overview

Best Publications

• Aspartic proteases of Plasmodium falciparum and other parasitic protozoa as drug targets

  Graham H. Coombs;Daniel E. Goldberg;Michael Klemba;Colin Berry

  421
  Citations

• The V3 loops of the HIV-1 and HIV-2 surface glycoproteins contain proteolytic cleavage sites: a possible function in viral fusion?

  Gary J. Clements;Molly J. Price-Jones;Paul E. Stephens;Christopher Sutton

  310
  Citations

• Antigen processing for presentation by class II major histocompatibility complex requires cleavage by cathepsin E.

  Bennett K;Levine T;Ellis Js;Peanasky Rj

  258
  Citations

• Effective blocking of HIV-1 proteinase activity by characteristic inhibitors of aspartic proteinases.

  Anthony D. Richards;Ray Roberts;Ben M. Dunn;Mary C. Graves

  257
  Citations

• Aspartic proteinases and their inhibitors.

  John Kay

  242
  Citations

• A systematic series of synthetic chromophoric substrates for aspartic proteinases.

  B M Dunn;M Jimenez;B F Parten;M J Valler

  240
  Citations

• Immunolocalization of cathepsin D in normal and neoplastic human tissues.

  W A Reid;M J Valler;J Kay

  175
  Citations

• Viral proteinases: weakness in strength.

  John Kay;Ben M. Dunn

  166
  Citations

• High resolution X-ray analyses of renin inhibitor-aspartic proteinase complexes

  S. I. Foundling;J. Cooper;F. E. Watson;A. Cleasby

  159
  Citations

• Sequence, expression and modeled structure of an aspartic proteinase from the human malaria parasite Plasmodium falciparum.

  John B. Dame;G.Roman Reddy;Charles A. Yowell;Ben M. Dunn

  153
  Citations

• Different requirements for productive interaction between the active site of HIV-1 proteinase and substrates containing -hydrophobic*hydrophobic- or -aromatic*pro- cleavage sites.

  Jonathan T. Griffiths;Lowri H. Phylip;Jan Konvalinka;Petr Strop

  151
  Citations

• High level expression and characterisation of Plasmepsin II, an aspartic proteinase from Plasmodium falciparum

  Jeffrey Hill;Lorraine Tyas;Lowri H. Phylip;John Kay

  150
  Citations

• Expression and characterisation of plasmepsin I from Plasmodium falciparum.

  Richard P. Moon;Lorraine Tyas;Ulrich Certa;Katharina Rupp

  145
  Citations

• Presence and possible significance of immunocytochemically demonstrable metallothionein over-expression in primary invasive ductal carcinoma of the breast.

  K. W. Schmid;I. O. Ellis;Julia Margaret Wendy Gee;Barbara M. Darke

  145
  Citations

• Slow moving proteinase: Isolation, characterization, and immunohistochemical localization in gastric mucosa

  I.M. Samloff;R.T. Taggart;T. Shiraishi;T. Branch

  139
  Citations

• The aspartic proteinase from Saccharomyces cerevisiae folds its own inhibitor into a helix.

  Mi Li;Lowri H. Phylip;Wendy E. Lees;Jakob R. Winther

  131
  Citations

• The Botrytis cinerea aspartic proteinase family

  Arjen ten Have;José J. Espino;Ester Dekkers;Steven C. Van Sluyter;Steven C. Van Sluyter

  116
  Citations

• A plant metallothionein produced in E. coli.

  Peter Kille;Dennis R. Winge;John L. Harwood;John Kay

  115
  Citations

• A comparison of the cadmium-binding proteins isolated from the posterior alimentary canal of the earthworms Dendrodrilus rubidus and Lumbricus rubellus

  J.E. Morgan;C.G. Norey;A.J. Morgan;J. Kay

  114
  Citations

• A distinct member of the aspartic proteinase gene family from the human malaria parasite Plasmodium falciparum

  Colin Berry;Michelle J Humphreys;Philip Matharu;Rachel Granger

  113
  Citations