James P. Bennett

Best Publications

• Parkinson's Disease Brain Mitochondrial Complex I Has Oxidatively Damaged Subunits and Is Functionally Impaired and Misassembled

  Paula M. Keeney;Jing Xie;Roderick A. Capaldi;James P. Bennett

  915
  Citations

• Origin and functional consequences of the complex I defect in Parkinson's disease

  Swerdlow Rh;Parks Jk;Miller Sw;Tuttle Jb

  813
  Citations

• An evaluation of the role of mitochondria in neurodegenerative diseases : mitochondrial mutations and oxidative pathology, protective nuclear responses, and cell death in neurodegeneration

  David S Cassarino;James P Bennett

  583
  Citations

• The parkinsonian neurotoxin MPP+ opens the mitochondrial permeability transition pore and releases cytochrome c in isolated mitochondria via an oxidative mechanism

  David S. Cassarino;Janice K. Parks;W.Davis Parker;James P. Bennett

  431
  Citations

• Efficacy of pramipexole, a novel dopamine agonist, as monotherapy in mild to moderate Parkinson's disease

  Shannon Km;Bennett Jp;Friedman Jh

  400
  Citations

• Cybrids in Alzheimer's disease: A cellular model of the disease?

  R. H. Swerdlow;J. K. Parks;D. S. Cassarino;D. J. Maguire

  379
  Citations

• Abnormal Mitochondrial Morphology in Sporadic Parkinson's and Alzheimer's Disease Cybrid Cell Lines

  Patricia A. Trimmer;Russell H. Swerdlow;Janice K. Parks;Paula Keeney

  372
  Citations

• Neurotransmitter Receptors in Frontal Cortex of Schizophrenics

  James P. Bennett;Salvatore J. Enna;David B. Bylund;J. Christian Gillin

  358
  Citations

• Elevated reactive oxygen species and antioxidant enzyme activities in animal and cellular models of Parkinson's disease.

  David S Cassarino;Christopher P Fall;Russell H Swerdlow;Trisha S Smith

  339
  Citations

• Postmenopausal estrogen use affects risk for Parkinson disease.

  Lillian J. Currie;Madaline B. Harrison;Joel M. Trugman;James P. Bennett

  309
  Citations

• Pramipexole reduces reactive oxygen species production in vivo and in vitro and inhibits the mitochondrial permeability transition produced by the parkinsonian neurotoxin methylpyridinium ion.

  David S. Cassarino;Christopher P. Fall;Trisha S. Smith;James P. Bennett

  295
  Citations

• Neurotensin, a central nervous system peptide: apparent receptor binding in brain membranes

  George R. Uhl;James P. Bennett;Solomon H. Snyder

  291
  Citations

• Neurotoxic Abeta peptides increase oxidative stress in vivo through NMDA-receptor and nitric-oxide-synthase mechanisms, and inhibit complex IV activity and induce a mitochondrial permeability transition in vitro.

  Janice K. Parks;Trisha S. Smith;Patricia A. Trimmer;James P. Bennett

  288
  Citations

• Neuroinflammation in Alzheimer's Disease.

  Isaac G. Onyango;Gretsen V. Jauregui;Mária Čarná;James P. Bennett

  276
  Citations

• Huntington's chorea. Changes in neurotransmitter receptors in the brain.

  Salvatore J. Enna;Edward D. Bird;James P. Bennett;David B. Bylund

  256
  Citations

• Stereospecific binding of D-lysergic acid diethylamide (LSD) to brain membranes: relationship to serotonin receptors.

  James P. Bennett;Solomon H. Snyder

  240
  Citations

• Pramipexole--a new dopamine agonist for the treatment of Parkinson's disease.

  James P Bennett;Montford F Piercey

  221
  Citations

• Mitochondria in Sporadic Amyotrophic Lateral Sclerosis

  Swerdlow Rh;Parks Jk;Cassarino Ds;Trimmer Pa

  219
  Citations

• Matrilineal inheritance of complex I dysfunction in a multigenerational Parkinson's disease family

  Russell H. Swerdlow;Janice K. Parks;John N. Davis;David S. Cassarino

  204
  Citations

• Dopamine neurons from transgenic mice with a knockout of the p53 gene resist MPTP neurotoxicity

  Patricia A. Trimmer;Trisha S. Smith;Anthony B. Jung;James P. Bennett

  193
  Citations

• Mitochondrial toxins in models of neurodegenerative diseases. I: in vivo brain hydroxyl radical production during sytemic MPTP treatment or following microdialysis infusion of methylpyridinium or azide ions

  Trisha S Smith;James P Bennett

  185
  Citations

• Apparent synaptic dopamine deficiency induced by withdrawal from chronic cocaine treatment

  Matthew W. Robertson;Catherine A. Leslie;James P. Bennett

  181
  Citations

• Alterations of brain neurotransmitter receptor binding in Huntington's chorea.

  S.J. Enna;James P. Bennett;David B. Bylund;Solomon H. Snyder

  181
  Citations