World's Best Scientists 2026 revealed!

D-Index & Metrics

Immunology

D-Index
76
Citations
23949
World Ranking
1888
National Ranking
919

Overview

James J. Mulé is affiliated with the University of South Florida in the United States. Their research primarily focuses on fields within Medicine and Immunology and Microbiology. Their work encompasses Oncology, Immunology, Pulmonary and Respiratory Medicine, Molecular Biology, and Surgery.

The scientist's research includes several specific topics such as Cancer Immunotherapy and Biomarkers, Immunotherapy and Immune Responses, Renal Cell Carcinoma Treatment, Immune Cells in Cancer, Bladder and Urothelial Cancer Treatments, CAR-T Cell Therapy Research, and Single-cell and Spatial Transcriptomics.

Among their recent papers are:

  • Epigenetic reprogramming of tumor cell-intrinsic STING function sculpts antigenicity and T cell recognition of melanoma, 2021, Proceedings of the National Academy of Sciences
  • Sirt2 Inhibition Enhances Metabolic Fitness and Effector Functions of Tumor-Reactive T Cells, 2020, Cell Metabolism
  • Epigenetic state determines the in vivo efficacy of STING agonist therapy, 2023, Nature Communications
  • Expanded Tumor-infiltrating Lymphocytes From Soft Tissue Sarcoma Have Tumor-specific Function, 2021, Journal of Immunotherapy
  • The Radiosensitivity Index Gene Signature Identifies Distinct Tumor Immune Microenvironment Characteristics Associated With Susceptibility to Radiation Therapy, 2022, International Journal of Radiation Oncology*Biology*Physics

Their frequent coauthors include:

  • Anders Berglund
  • Jasreman Dhillon
  • Shari Pilon-Thomas
  • Nicholas H. Chakiryan
  • Carlos Moran Segura

James J. Mulé commonly publishes in these venues:

  • Regular and Young Investigator Award Abstracts
  • The Journal of Urology
  • Journal for ImmunoTherapy of Cancer
  • Cancers
  • Journal of Clinical Oncology

Best Publications

  • Inhibiting Stat3 signaling in the hematopoietic system elicits multicomponent antitumor immunity.

    Marcin Kortylewski;Maciej Kujawski;Tianhong Wang;Sheng Wei

  • Bif-1 interacts with Beclin 1 through UVRAG and regulates autophagy and tumorigenesis.

    Yoshinori Takahashi;Domenico Coppola;Norimasa Matsushita;Hernani D. Cualing

  • Regression of established pulmonary metastases and subcutaneous tumor mediated by the systemic administration of high-dose recombinant interleukin 2.

    Steven A. Rosenberg;James J. Mulé;Paul J. Spiess;Cheryl M. Reichert

  • Adoptive immunotherapy of established pulmonary metastases with LAK cells and recombinant interleukin-2.

    James J. Mulé;Suyu Shu;Susan L. Schwarz;Steven A. Rosenberg

  • Design and Function of a Dendrimer-Based Therapeutic Nanodevice Targeted to Tumor Cells Through the Folate Receptor

    Antonio Quintana;Ewa Raczka;Lars Piehler;Inhan Lee

  • Identification of human cancers deficient in antigen processing.

    Nicholas P. Restifo;Fernando Esquivel;Yutaka Kawakami;Jonathan W. Yewdell

  • Interferon gamma and tumor necrosis factor have a role in tumor regressions mediated by murine CD8+ tumor-infiltrating lymphocytes.

    R J Barth;J J Mulé;P J Spiess;S A Rosenberg

  • Neutralization of Tumor Acidity Improves Antitumor Responses to Immunotherapy.

    Shari Pilon-Thomas;Krithika N. Kodumudi;Asmaa E. El-Kenawi;Shonagh Russell

  • Murine dendritic cells pulsed with whole tumor lysates mediate potent antitumor immune responses<i>in vitro</i>and<i>in vivo</i>

    Unknown

  • 12-Chemokine Gene Signature Identifies Lymph Node-like Structures in Melanoma: Potential for Patient Selection for Immunotherapy?

    Jane L. Messina;David A. Fenstermacher;Steven Eschrich;Xiaotao Qu

  • Unique Ectopic Lymph Node-Like Structures Present in Human Primary Colorectal Carcinoma Are Identified by Immune Gene Array Profiling

    Domenico Coppola;Michael Nebozhyn;Farah Khalil;Hongyue Dai

  • Murine tumor cells transduced with the gene for tumor necrosis factor-alpha. Evidence for paracrine immune effects of tumor necrosis factor against tumors.

    A. L. Asher;J. J. Mule;A.K Kasid;N. P. Restifo

  • Vaccination Of Pediatric Solid Tumor Patients with Tumor Lysate-pulsed Dendritic Cells Can Expand Specific T Cells and Mediate Tumor Regression

    James D. Geiger;Raymond J. Hutchinson;Lyndon F. Hohenkirk;Elizabeth A. McKenna

  • Studies on the anti-tumor efficacy of systemically administered recombinant tumor necrosis factor against several murine tumors in vivo.

    A Asher;J J Mulé;C M Reichert;E Shiloni

  • The anti-tumor efficacy of lymphokine-activated killer cells and recombinant interleukin 2 in vivo.

    J J Mulé;S Shu;S A Rosenberg

  • Experimental and Clinical Studies of Cytokine Gene-Modified Tumor Cells

    Robert I. Tepper;James J. Mulé

  • Antitumor activity of recombinant interleukin 6 in mice.

    J J Mulé;J K McIntosh;D M Jablons;S A Rosenberg

  • Identification of cellular mechanisms operational in vivo during the regression of established pulmonary metastases by the systemic administration of high-dose recombinant interleukin 2.

    J. J. Mule;J. C. Yang;R. L. Afreniere;Suyu Shu

  • Comparative analysis of necrotic and apoptotic tumor cells as a source of antigen(s) in dendritic cell-based immunization.

    Yoshihito Kotera;Koichi Shimizu;James J. Mulé

  • NIH conference. New approaches to the immunotherapy of cancer using interleukin-2

    Steven A. Rosenberg;Michael T. Lotze;James J. Mulé

  • A Phase I Trial of Tumor Lysate-pulsed Dendritic Cells in the Treatment of Advanced Cancer

    Alfred E. Chang;Bruce G. Redman;Joel R. Whitfield;Brian J. Nickoloff

Frequent Co-Authors

Steven A. Rosenberg
Steven A. Rosenberg National Institutes of Health
Jeffrey S. Weber
Jeffrey S. Weber New York University
Nicholas P. Restifo
Nicholas P. Restifo National Institutes of Health
Vernon K. Sondak
Vernon K. Sondak University of South Florida
James Chih-Hsin Yang
James Chih-Hsin Yang National Taiwan University
Peter A. Cohen
Peter A. Cohen Mayo Clinic
David M. Jablons
David M. Jablons University of California, San Francisco
Alfred E. Chang
Alfred E. Chang University of Michigan–Ann Arbor
Domenico Coppola
Domenico Coppola Moffitt Cancer Center
Patrick Hwu
Patrick Hwu The University of Texas MD Anderson Cancer Center

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

For those interested in Immunology, pursuing related online degrees can open diverse career opportunities in healthcare and research. Many students begin by exploring online absn programs for non nurses, which are designed to quickly transition individuals without nursing backgrounds into the nursing profession.

If you’re seeking a faster entry into nursing, considering the easiest accelerated nursing programs to get into can be a practical choice. These programs often have streamlined admissions processes yet maintain essential training standards.

Another option includes enrolling in easy admission lpn programs, which provide foundational skills to work as licensed practical nurses in various clinical settings, often serving as stepping-stones for advanced degrees in immunology-related healthcare roles.

For advanced practice, consider nurse practitioner programs with easy admission. These programs prepare graduates to take on specialized roles, integrating immunology knowledge in patient care, research, and policy-making.

Choosing the right pathway depends on your background, career goals, and desired pace of education. Access to flexible online programs helps bridge the gap between immunology and practical healthcare applications.

Best Scientists Citing James J. Mulé

Trending Scientists

Recently Published Articles