James Brett Case

Best Publications

• Cross-neutralization of SARS-CoV-2 by a human monoclonal SARS-CoV antibody.

  Dora Pinto;Young Jun Park;Martina Beltramello;Alexandra C. Walls

  2501
  Citations

• Broad-spectrum antiviral GS-5734 inhibits both epidemic and zoonotic coronaviruses

  Timothy P. Sheahan;Amy C. Sims;Rachel L. Graham;Vineet D. Menachery

  1740
  Citations

• Coronavirus Susceptibility to the Antiviral Remdesivir (GS-5734) Is Mediated by the Viral Polymerase and the Proofreading Exoribonuclease

  Maria L. Agostini;Erica L. Andres;Amy C Sims;Rachel Lauren Graham

  1350
  Citations

• Potently neutralizing and protective human antibodies against SARS-CoV-2.

  Seth J. Zost;Pavlo Gilchuk;James Brett Case;Elad Binshtein

  1155
  Citations

• SARS-CoV-2 Omicron virus causes attenuated disease in mice and hamsters

  Unknown

  1076
  Citations

• Resistance of SARS-CoV-2 variants to neutralization by monoclonal and serum-derived polyclonal antibodies.

  Rita E. Chen;Xianwen Zhang;James Brett Case;Emma S. Winkler

  881
  Citations

• SARS-CoV-2 mRNA vaccines induce persistent human germinal centre responses.

  Jackson S. Turner;Jane A. O’Halloran;Elizaveta Kalaidina;Wooseob Kim

  799
  Citations

• Extrafollicular B cell responses correlate with neutralizing antibodies and morbidity in COVID-19.

  Matthew C. Woodruff;Richard P. Ramonell;Doan C. Nguyen;Kevin S. Cashman

  724
  Citations

• De novo design of picomolar SARS-CoV-2 miniprotein inhibitors.

  Longxing Cao;Inna Goreshnik;Brian Coventry;James Brett Case

  688
  Citations

• Rapid isolation and profiling of a diverse panel of human monoclonal antibodies targeting the SARS-CoV-2 spike protein.

  Seth J. Zost;Pavlo Gilchuk;Rita E. Chen;James Brett Case

  605
  Citations

• A Single-Dose Intranasal ChAd Vaccine Protects Upper and Lower Respiratory Tracts against SARS-CoV-2.

  Ahmed O. Hassan;Natasha M. Kafai;Igor P. Dmitriev;Julie M. Fox

  604
  Citations

• Ultrapotent human antibodies protect against SARS-CoV-2 challenge via multiple mechanisms

  M. Alejandra Tortorici;M. Alejandra Tortorici;Martina Beltramello;Florian A. Lempp;Dora Pinto

  559
  Citations

• A SARS-CoV-2 Infection Model in Mice Demonstrates Protection by Neutralizing Antibodies.

  Ahmed O. Hassan;James Brett Case;Emma S. Winkler;Larissa B. Thackray

  538
  Citations

• Neutralizing Antibody and Soluble ACE2 Inhibition of a Replication-Competent VSV-SARS-CoV-2 and a Clinical Isolate of SARS-CoV-2.

  James Brett Case;Paul W Rothlauf;Rita E Chen;Zhuoming Liu

  461
  Citations

• Neutralizing Antibody and Soluble ACE2 Inhibition of a Replication-Competent VSV-SARS-CoV-2 and a Clinical Isolate of SARS-CoV-2

  James Brett Case;Paul W. Rothlauf;Paul W. Rothlauf;Rita E. Chen;Zhuoming Liu

  437
  Citations

• Human neutralizing antibodies against SARS-CoV-2 require intact Fc effector functions for optimal therapeutic protection.

  Emma S. Winkler;Pavlo Gilchuk;Jinsheng Yu;Adam L. Bailey

  358
  Citations

• Genetic and structural basis for SARS-CoV-2 variant neutralization by a two-antibody cocktail.

  Jinhui Dong;Seth J Zost;Allison J Greaney;Allison J Greaney;Tyler N Starr

  280
  Citations

• Growth, detection, quantification, and inactivation of SARS-CoV-2.

  James Brett Case;Adam L. Bailey;Arthur S. Kim;Rita E. Chen

  272
  Citations

• Resilience of S309 and AZD7442 monoclonal antibody treatments against infection by SARS-CoV-2 Omicron lineage strains

  Unknown

  248
  Citations

• In vivo monoclonal antibody efficacy against SARS-CoV-2 variant strains.

  Rita E. Chen;Emma S. Winkler;James Brett Case;Ishmael D. Aziati

  227
  Citations