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Neuroscience

D-Index
41
Citations
6542
World Ranking
7873
National Ranking
3383

Overview

Jack W. Lipton is affiliated with Michigan State University in the United States. Their research primarily spans the fields of Medicine and Neuroscience, with a significant focus on subfields such as Neurology, Cellular and Molecular Neuroscience, Infectious Diseases, Molecular Biology, and Polymers and Plastics.

The scientist's work addresses a range of main topics, including:

  • Parkinson's Disease Mechanisms and Treatments
  • Nuclear Receptors and Signaling
  • Neurological disorders and treatments
  • RNA regulation and disease
  • Conducting polymers and applications
  • Nerve injury and regeneration
  • Autism Spectrum Disorder Research

Frequent publication venues for the scientist include:

  • Journal of Visualized Experiments
  • JCI Insight
  • Neurobiology of Disease
  • Neurotherapeutics
  • Experimental Neurology

Their recent papers demonstrate a focus on Parkinson's disease and related neurological studies:

  • "α-Synuclein antisense oligonucleotides as a disease-modifying therapy for Parkinson's disease" (2021), published in JCI Insight
  • "Developmental exposure to the organochlorine pesticide dieldrin causes male-specific exacerbation of α-synuclein-preformed fibril-induced toxicity and motor deficits" (2020), published in Neurobiology of Disease
  • "BDNF rs6265 Variant Alters Outcomes with Levodopa in Early-Stage Parkinson's Disease" (2020), published in Neurotherapeutics
  • "Striatal Nurr1, but not FosB expression links a levodopa-induced dyskinesia phenotype to genotype in Fisher 344 vs. Lewis hemiparkinsonian rats" (2020), published in Experimental Neurology
  • "BDNF rs6265 Genotype Influences Outcomes of Pharmacotherapy and Subthalamic Nucleus Deep Brain Stimulation in Early-Stage Parkinson's Disease" (2021), published in Neuromodulation Technology at the Neural Interface

Collaborations have included frequent co-authors such as:

  • Caryl E. Sortwell
  • Allyson Cole-Strauss
  • Joseph R. Patterson
  • Nathan C. Kuhn
  • Kelvin C. Luk

Best Publications

  • Differentiation of Mesencephalic Progenitor Cells into Dopaminergic Neurons by Cytokines

    Zao Dung Ling;Elizabeth D. Potter;Jack W. Lipton;Paul M. Carvey

  • Intrastriatal injection of pre-formed mouse α-synuclein fibrils into rats triggers α-synuclein pathology and bilateral nigrostriatal degeneration

    Katrina L. Paumier;Kelvin C. Luk;Fredric P. Manfredsson;Nicholas M. Kanaan

  • Exposure to elevated levels of dietary fat attenuates psychostimulant reward and mesolimbic dopamine turnover in the rat.

    Jon F. Davis;Andrea L. Tracy;Jennifer D. Schurdak;Matthias H. Tschöp

  • In utero bacterial endotoxin exposure causes loss of tyrosine hydroxylase neurons in the postnatal rat midbrain.

    ZaoDung D. Ling;Dave A. Gayle;Shang Yong Ma;Jack W. Lipton

  • Tumor Necrosis Factor α Is Toxic to Embryonic Mesencephalic Dopamine Neurons

    Susan O McGuire;Zao Dung Ling;Jack W Lipton;Caryl E Sortwell

  • Lipopolysaccharide (LPS)-induced dopamine cell loss in culture: roles of tumor necrosis factor-α, interleukin-1β, and nitric oxide

    Dave A Gayle;ZaoDung Ling;ChongWai Tong;Teresa Landers

  • Prenatal exposure to the bacteriotoxin lipopolysaccharide leads to long-term losses of dopamine neurons in offspring: a potential, new model of Parkinson's disease.

    Paul M Carvey;Qin Chang;Jack W Lipton;Zaodung Ling

  • Aging-related changes in the nigrostriatal dopamine system and the response to MPTP in nonhuman primates: Diminished compensatory mechanisms as a prelude to parkinsonism

    Timothy J. Collier;Jack Lipton;Brian F. Daley;Stephane Palfi

  • Progressive dopamine neuron loss following supra-nigral lipopolysaccharide (LPS) infusion into rats exposed to LPS prenatally.

    Zaodung Ling;Yuangui Zhu;Chong wai Tong;Joshua A. Snyder

  • Leptin Regulates Energy Balance and Motivation Through Action at Distinct Neural Circuits

    Jon F. Davis;Derrick L. Choi;Jennifer D. Schurdak;Maureen F. Fitzgerald

  • Rotenone potentiates dopamine neuron loss in animals exposed to lipopolysaccharide prenatally.

    Zaodung Ling;Qin A. Chang;Chong Wai Tong;Susan E. Leurgans

  • Combined toxicity of prenatal bacterial endotoxin exposure and postnatal 6-hydroxydopamine in the adult rat midbrain

    Z.D Ling;Q Chang;J.W Lipton;C.W Tong

  • Stimulation of the rat subthalamic nucleus is neuroprotective following significant nigral dopamine neuron loss

    A.L. Spieles-Engemann;M.M. Behbehani;T.J. Collier;S.L. Wohlgenant

  • Orexin signaling in the paraventricular thalamic nucleus modulates mesolimbic dopamine and hedonic feeding in the rat

    Derrick L. Choi;Jon F. Davis;Irwin J Magrisso;Maureen E. Fitzgerald

  • Omega-3 fatty acid deficiency increases constitutive pro-inflammatory cytokine production in rats: Relationship with central serotonin turnover

    Robert K. McNamara;Ronald Jandacek;Therese Rider;Patrick Tso

  • Omega-3 fatty acid deficiency during perinatal development increases serotonin turnover in the prefrontal cortex and decreases midbrain tryptophan hydroxylase-2 expression in adult female rats: Dissociation from estrogenic effects

    Robert K. McNamara;Jessica Able;Yanhong Liu;Ronald Jandacek

  • Is Alpha-Synuclein Loss-of-Function a Contributor to Parkinsonian Pathology? Evidence from Non-human Primates.

    Timothy J. Collier;Timothy J. Collier;D. Eugene Redmond;Kathy Steece-Collier;Kathy Steece-Collier;Jack W. Lipton;Jack W. Lipton

  • Subthalamic Nucleus Stimulation Increases Brain Derived Neurotrophic Factor in the Nigrostriatal System and Primary Motor Cortex

    Anne L. Spieles-Engemann;Kathy Steece-Collier;Michael M. Behbehani;Timothy J. Collier

  • α-Synuclein antisense oligonucleotides as a disease-modifying therapy for Parkinson's disease.

    Tracy A. Cole;Hien Zhao;Timothy J. Collier;Ivette Sandoval

  • Parkinson's disease-linked D620N VPS35 knockin mice manifest tau neuropathology and dopaminergic neurodegeneration.

    Xi Chen;Jennifer K. Kordich;Erin T. Williams;Nathan Levine

  • Intra-parenchymal injection of tumor necrosis factor-α and interleukin 1-β produces dopamine neuron loss in the rat

    P. M. Carvey;E.-Y. Chen;J. W. Lipton;C. W. Tong

  • Continuous cocaine administration produces persisting changes in brain neurochemistry and behavior.

    Steve Zeigler;Jack Lipton;Arthur Toga;Gaylord Ellison

  • Diaphragm pacing with a quadripolar phrenic nerve electrode: an international study.

    Debra E. Weese-Mayer;Jean M. Silvestri;Anna S. Kenny;Michel N. Ilbawi

Frequent Co-Authors

Caryl E. Sortwell
Caryl E. Sortwell Michigan State University
Paul M. Carvey
Paul M. Carvey Rush University Medical Center
Kathy Steece-Collier
Kathy Steece-Collier Michigan State University
James B. Koprich
James B. Koprich Fudan University
Nicholas M. Kanaan
Nicholas M. Kanaan Michigan State University
Stephen C. Benoit
Stephen C. Benoit University of Cincinnati
Robert K. McNamara
Robert K. McNamara University of Cincinnati Medical Center
Jeffrey H. Kordower
Jeffrey H. Kordower Arizona State University
Gaylord Ellison
Gaylord Ellison University of California, Los Angeles
Neil M. Richtand
Neil M. Richtand University of California - San Diego School of Medicine

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