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Neuroscience

D-Index
39
Citations
5068
World Ranking
8390
National Ranking
139

Overview

Maria J. Guerra is affiliated with the University of Santiago de Compostela in Spain. Their research primarily lies within the field of Medicine, with focused contributions in Cardiology and Cardiovascular Medicine, Neurology, Molecular Biology, Immunology, and Physiology.

Their work addresses multiple main topics, including:

  • Alzheimer's disease research and treatments
  • Parkinson's Disease Mechanisms and Treatments
  • Cardiovascular Function and Risk Factors
  • Renin-Angiotensin System Studies
  • Receptor Mechanisms and Signaling
  • Mast cells and histamine
  • Nuclear Receptors and Signaling

Maria J. Guerra has contributed to several recent papers, documenting advances in neurodegeneration, neuroinflammation, and neurovascular interactions. Notable publications include:

  • "The role of the brain renin-angiotensin system in Parkinson´s disease," 2024, Translational Neurodegeneration
  • "Interactions between Angiotensin Type-1 Antagonists, Statins, and ROCK Inhibitors in a Rat Model of L-DOPA-Induced Dyskinesia," 2023, Antioxidants
  • "Modulation of Mitochondrial Dynamics by the Angiotensin System in Dopaminergic Neurons and Microglia," 2024, Aging and Disease
  • "Serum angiotensin type-1 receptor autoantibodies and neurofilament light chain as markers of neuroaxonal damage in post-COVID patients," 2025, Frontiers in Immunology
  • "Association between serum myeloperoxidase enzyme activity and Parkinson's disease status," 2025, npj Parkinson s Disease

Frequent collaborators in Maria J. Guerra's research include José L. Labandeira-García, Ana I. Rodríguez-Pérez, Carmen M. Labandeira, Andrea López-López, and Rita Valenzuela. Collaborations with these co-authors have resulted in multiple publications, indicating sustained research partnerships.

Their publications appear in various research venues, with multiple contributions to Zenodo (CERN European Organization for Nuclear Research), and articles in Translational Neurodegeneration, Aging and Disease, Antioxidants, and Frontiers in Immunology.

Best Publications

  • An automated rotarod method for quantitative drug-free evaluation of overall motor deficits in rat models of parkinsonism

    G Rozas;M.J Guerra;J.L Labandeira-Garcı́a

  • The overall rod performance test in the MPTP-treated-mouse model of Parkinsonism

    G Rozas;E López-Martı́n;M.J Guerra;J.L Labandeira-Garcı́a

  • Mechanism of 6-hydroxydopamine neurotoxicity: the role of NADPH oxidase and microglial activation in 6-hydroxydopamine-induced degeneration of dopaminergic neurons

    J. Rodriguez-Pallares;J. A. Parga;A. Muñoz;P. Rey

  • Brain Renin-Angiotensin System and Microglial Polarization: Implications for Aging and Neurodegeneration.

    Jose L. Labandeira-Garcia;Ana I. Rodríguez-Perez;Pablo Garrido-Gil;Jannette Rodriguez-Pallares

  • Brain angiotensin enhances dopaminergic cell death via microglial activation and NADPH-derived ROS.

    J. Rodriguez-Pallares;P. Rey;J.A. Parga;A. Muñoz

  • The inflammatory response in the MPTP model of Parkinson's disease is mediated by brain angiotensin: relevance to progression of the disease.

    Belen Joglar;Jannette Rodriguez-Pallares;Ana Isabel Rodriguez-Perez;Pablo Rey

  • Involvement of PPAR-γ in the neuroprotective and anti-inflammatory effects of angiotensin type 1 receptor inhibition: effects of the receptor antagonist telmisartan and receptor deletion in a mouse MPTP model of Parkinson's disease

    Pablo Garrido-Gil;Belen Joglar;Ana I Rodriguez-Perez;Maria J Guerra

  • Interaction between NADPH-oxidase and Rho-kinase in angiotensin II-induced microglial activation

    Ana I. Rodriguez-Perez;Ana Borrajo;Jannette Rodriguez-Pallares;Maria J. Guerra

  • Involvement of microglial RhoA/Rho-kinase pathway activation in the dopaminergic neuron death. Role of angiotensin via angiotensin type 1 receptors.

    Begoña Villar-Cheda;Antonio Dominguez-Meijide;Belen Joglar;Ana I. Rodriguez-Perez

  • Sprouting of the serotonergic afferents into striatum after selective lesion of the dopaminergic system by MPTP in adult mice.

    G Rozas;I Liste;M.J Guerra;J.L Labandeira-Garcia

  • Mechanisms of the effects of exogenous levodopa on the dopamine-denervated striatum.

    A Lopez;A Muñoz;M.J Guerra;J.L Labandeira-Garcia

  • Aging-related changes in the nigral angiotensin system enhances proinflammatory and pro-oxidative markers and 6-OHDA-induced dopaminergic degeneration

    Begoña Villar-Cheda;Rita Valenzuela;Ana I. Rodriguez-Perez;Maria J. Guerra

  • Bidirectional Neural Interaction Between Central Dopaminergic and Gut Lesions in Parkinson’s Disease Models

    Pablo Garrido-Gil;Ana I. Rodriguez-Perez;Antonio Dominguez-Meijide;Maria J. Guerra

  • Dopamine modulates astroglial and microglial activity via glial renin-angiotensin system in cultures.

    Antonio Dominguez-Meijide;Ana I. Rodriguez-Perez;Carmen Diaz-Ruiz;Maria J. Guerra

  • Reduction of dopaminergic degeneration and oxidative stress by inhibition of angiotensin converting enzyme in a MPTP model of parkinsonism.

    Ana Muñoz;Pablo Rey;Maria J. Guerra;Estefania Mendez-Alvarez

  • Nigral and striatal regulation of angiotensin receptor expression by dopamine and angiotensin in rodents: implications for progression of Parkinson’s disease

    Begoña Villar-Cheda;Jannette Rodríguez-Pallares;Rita Valenzuela;Ana Muñoz

  • Inhibition of Rho kinase mediates the neuroprotective effects of estrogen in the MPTP model of Parkinson's disease.

    Ana I. Rodriguez-Perez;Antonio Dominguez-Meijide;Jose L. Lanciego;Maria J. Guerra

  • Inhibition of the microglial response is essential for the neuroprotective effects of Rho-kinase inhibitors on MPTP-induced dopaminergic cell death.

    Ana Borrajo;Ana I. Rodriguez-Perez;Begoña Villar-Cheda;Maria J. Guerra

  • Localization and functional significance of striatal neurons immunoreactive to aromatic L-amino acid decarboxylase or tyrosine hydroxylase in rat Parkinsonian models.

    Ana Lopez-Real;Jannette Rodriguez-Pallares;Maria J. Guerra;Jose L. Labandeira-Garcia

  • Cortical stimulation induces Fos expression in striatal neurons via NMDA glutamate and dopamine receptors

    I. Liste;G. Rozas;M.J. Guerra;J.L. Labandeira-Garcia

  • Estrogen and angiotensin interaction in the substantia nigra. Relevance to postmenopausal Parkinson's disease.

    Ana I. Rodriguez-Perez;Rita Valenzuela;Begoña Villar-Cheda;Maria J. Guerra

Frequent Co-Authors

Jose L. Labandeira-Garcia
Jose L. Labandeira-Garcia University of Santiago de Compostela
José L. Lanciego
José L. Lanciego University of Navarra
Rosario Moratalla
Rosario Moratalla Spanish National Research Council

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