World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
70
Citations
18318
World Ranking
6982
National Ranking
3212

Overview

J. Thomas Brenna is affiliated with The University of Texas at Austin in the United States. Their research contributes significantly to the fields of biochemistry, genetics, molecular biology, and medicine, with a strong focus on nutrition and dietetics. Over their career, they have published extensively on topics related to fatty acid research and health, eicosanoids and hypertension pharmacology, as well as cancer, lipids, and metabolism.

The scientist has contributed to a variety of research areas, reflecting a multidisciplinary approach to understanding metabolic and nutritional processes. Their main fields of study include:

  • Biochemistry, Genetics and Molecular Biology
  • Medicine

Their work spans multiple subfields such as:

  • Nutrition and Dietetics
  • Molecular Biology
  • Cancer Research
  • Biochemistry
  • Physiology

J. Thomas Brenna's research covers several main topics including:

  • Fatty Acid Research and Health
  • Eicosanoids and Hypertension Pharmacology
  • Cancer, Lipids, and Metabolism
  • Nutritional Studies and Diet
  • Diet and Metabolism Studies
  • Cancer, Hypoxia, and Metabolism
  • Metabolomics and Mass Spectrometry Studies

Their recent publications include the following notable papers:

  • "Polyunsaturated fatty acids and fatty acid-derived lipid mediators: Recent advances in the understanding of their biosynthesis, structures, and functions" (2022, Progress in Lipid Research)
  • "Saturated Fats and Health: A Reassessment and Proposal for Food-Based Recommendations" (2020, Journal of the American College of Cardiology)
  • "Dietary Saturated Fats and Health: Are the U.S. Guidelines Evidence-Based?" (2021, Nutrients)
  • "Polyunsaturated fatty acid biosynthesis pathway and genetics. implications for interindividual variability in prothrombotic, inflammatory conditions such as COVID-19" (2020, Prostaglandins Leukotrienes and Essential Fatty Acids)
  • "Genome-wide association study of fish oil supplementation on lipid traits in 81,246 individuals reveals new gene-diet interaction loci" (2021, PLoS Genetics)

The scientist frequently publishes in several venues, indicating an active engagement with the research community. Some of these publication venues include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Current Developments in Nutrition
  • Prostaglandins Leukotrienes and Essential Fatty Acids
  • Journal of Agricultural and Food Chemistry
  • American Journal of Clinical Nutrition

J. Thomas Brenna collaborates regularly with other researchers. Frequent co-authors include:

  • Hui Gyu Park
  • Kumar S.D. Kothapalli
  • Dong Hao Wang
  • Zhen Wang
  • Kaixiong Ye

Best Publications

  • α-Linolenic acid supplementation and conversion to n-3 long-chain polyunsaturated fatty acids in humans

    J. Thomas Brenna;Norman Salem;Andrew J. Sinclair;Stephen C. Cunnane

  • Docosahexaenoic and arachidonic acid concentrations in human breast milk worldwide

    J Thomas Brenna;Behzad Varamini;Robert G Jensen;Deborah A Diersen-Schade

  • Efficiency of conversion of alpha-linolenic acid to long chain n-3 fatty acids in man.

    J Thomas Brenna

  • Dietary fat intakes for pregnant and lactating women

    Berthold Koletzko;Irene Cetin;J. Thomas Brenna

  • High‐precision continuous‐flow isotope ratio mass spectrometry

    J. Thomas Brenna;Thomas N. Corso;Herbert J. Tobias;Richard J. Caimi

  • Saturated Fats and Health: A Reassessment and Proposal for Food-based Recommendations: JACC State-of -the-Art Review

    Arne Astrup;Faidon Magkos;Dennis M. Bier;J. Thomas Brenna

  • The 2015 Dietary Guidelines Advisory Committee Scientific Report: Development and Major Conclusions

    Barbara E. Millen;Steve Abrams;Lucile Adams-Campbell;Cheryl A.M. Anderson

  • Breast-fed infants achieve a higher rate of brain and whole body docosahexaenoate accumulation than formula-fed infants not consuming dietary docosahexaenoate.

    Stephen C. Cunnane;Valerie Francescutti;J. Thomas Brenna;Michael A. Crawford

  • Highly unsaturated fatty acids in nature: what we know and what we need to learn

    Cornelia Wingfield Twining;J. Thomas Brenna;Nelson G. Hairston Jr.;Alexander S. Flecker

  • The influence of dietary docosahexaenoic acid and arachidonic acid on central nervous system polyunsaturated fatty acid composition.

    J. Thomas Brenna;Guan-Yeu Diau

  • Omega-3 long-chain polyunsaturated fatty acids support aerial insectivore performance more than food quantity

    Cornelia W. Twining;J. Thomas Brenna;Peter Lawrence;J. Ryan Shipley

  • Omega-3 fatty acids, energy substrates, and brain function during aging

    Erika Freemantle;Milène Vandal;Jennifer Tremblay-Mercier;Sébastien Tremblay

  • The influence of long chain polyunsaturate supplementation on docosahexaenoic acid and arachidonic acid in baboon neonate central nervous system.

    Guan Yeu Diau;Guan Yeu Diau;Andrea T. Hsieh;Eszter A. Sarkadi-Nagy;Eszter A. Sarkadi-Nagy;Vasuki Wijendran;Vasuki Wijendran

  • An alternate pathway to long-chain polyunsaturates: the FADS2 gene product Δ8-desaturates 20:2n-6 and 20:3n-3

    Woo Jung Park;Kumar S.D. Kothapalli;Peter Lawrence;Cynthia Tyburczy

  • Branched Chain Fatty Acids Reduce the Incidence of Necrotizing Enterocolitis and Alter Gastrointestinal Microbial Ecology in a Neonatal Rat Model

    Rinat R. Ran-Ressler;Ludmila Khailova;Kelly M. Arganbright;Camille K. Adkins-Rieck

  • Efficacy of dietary arachidonic acid provided as triglyceride or phospholipid as substrates for brain arachidonic acid accretion in baboon neonates.

    Vasuki Wijendran;Meng Chuan Huang;Guan Yeu Diau;Günther Boehm

  • Docosahexaenoic acid and human brain development: Evidence that a dietary supply is needed for optimal development

    J. Thomas Brenna;Susan E. Carlson

  • Desaturase and elongase-limiting endogenous long-chain polyunsaturated fatty acid biosynthesis:

    Ji Yao Zhang;Kumar S.D. Kothapalli;J. Thomas Brenna

  • Disruption of FADS2 gene in mice impairs male reproduction and causes dermal and intestinal ulceration

    Chad K. Stroud;Takayuki Y. Nara;Manuel Roqueta-Rivera;Emily C. Radlowski

  • Altered cholesterol and fatty acid metabolism in Huntington disease.

    Robert C. Block;E. Ray Dorsey;Christopher A. Beck;J. Thomas Brenna

Frequent Co-Authors

Stephen C. Cunnane
Stephen C. Cunnane Université de Sherbrooke
Ruth E. Ley
Ruth E. Ley Max Planck Society
Alexander S. Flecker
Alexander S. Flecker Cornell University
Steve N. Georas
Steve N. Georas University of Rochester Medical Center
Peter W. Nathanielsz
Peter W. Nathanielsz University of Wyoming
Jens Walter
Jens Walter National University of Ireland
William S. Harris
William S. Harris University of South Dakota
Shaker A. Mousa
Shaker A. Mousa Albany College of Pharmacy and Health Sciences
Berthold Koletzko
Berthold Koletzko Ludwig-Maximilians-Universität München
David W. Winkler
David W. Winkler Cornell University

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