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Microbiology

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Overview

Heidemarie Holzmann is affiliated with the Medical University of Vienna in Austria. Their research primarily spans the field of medicine, with significant contributions in hepatology, epidemiology, and infectious diseases.

The scientist's work covers subfields such as hepatology, epidemiology, infectious diseases, immunology, and public health, environmental and occupational health. Their research focuses on several main topics, including:

  • Hepatitis C virus research
  • Virology and viral diseases
  • Mosquito-borne diseases and control
  • Hepatitis B virus studies
  • Vector-borne infectious diseases
  • Viral infections and vectors
  • SARS-CoV-2 and COVID-19 research

Notable recent papers by Heidemarie Holzmann include:

  • "Variability of cycle threshold values in an external quality assessment scheme for detection of the SARS-CoV-2 virus genome by RT-PCR," 2020, Clinical Chemistry and Laboratory Medicine (CCLM)
  • "Response-guided long-term treatment of chronic hepatitis D patients with bulevirtide-results of a 'real world' study," 2022, Alimentary Pharmacology & Therapeutics
  • "Safety and effectiveness of up to 3 years' bulevirtide monotherapy in patients with HDV-related cirrhosis," 2021, Journal of Hepatology
  • "First results of a national external quality assessment scheme for the detection of SARS-CoV-2 genome sequences," 2020, Journal of Clinical Virology
  • "Hepatitis D virus (HDV) prevalence in Austria is low but causes considerable morbidity due to fast progression to cirrhosis," 2021, United European Gastroenterology Journal

Heidemarie Holzmann frequently collaborates with several researchers, including:

  • Karin Stiasny
  • Stephan W. Aberle
  • Thomas Reiberger
  • Mattias Mandorfer
  • Michael Trauner

Their publications appear predominantly in journals such as:

  • Journal of Hepatology
  • The Journal of Infectious Diseases
  • Liver International
  • Viruses
  • Eurosurveillance

The scope of Holzmann's research addresses multiple dimensions of infectious and viral diseases, with emphasis on hepatitis viruses and SARS-CoV-2. Their work contributes to understanding disease progression, treatment efficacy, and diagnostic standardization in clinical virology and hepatology contexts.

Best Publications

  • Structural Changes and Functional Control of the Tick-Borne Encephalitis Virus Glycoprotein E by the Heterodimeric Association with Protein prM

    Franz X. Heinz;Karin Stiasny;Gudrun Püschner-Auer;Heidemarie Holzmann

  • Antigenic structure of the flavivirus envelope protein E at the molecular level, using tick-borne encephalitis virus as a model.

    C. W. Mandl;Farshad Guirakhoo;H. Holzmann;F. X. Heinz

  • Adaptation of Tick-Borne Encephalitis Virus to BHK-21 Cells Results in the Formation of Multiple Heparan Sulfate Binding Sites in the Envelope Protein and Attenuation In Vivo

    Christian W. Mandl;Helga Kroschewski;Steven L. Allison;Regina Kofler

  • Field effectiveness of vaccination against tick-borne encephalitis

    Franz X. Heinz;Heidemarie Holzmann;Astrid Essl;Michael Kundi

  • Silibinin Is a Potent Antiviral Agent in Patients With Chronic Hepatitis C Not Responding to Pegylated Interferon/Ribavirin Therapy

    Peter Ferenci;Thomas–Matthias Scherzer;Heidrun Kerschner;Karoline Rutter

  • Cryptic Properties of a Cluster of Dominant Flavivirus Cross-Reactive Antigenic Sites

    Karin Stiasny;Stefan Kiermayr;Heidemarie Holzmann;Franz X. Heinz

  • Diagnosis of tick-borne encephalitis.

    Heidemarie Holzmann

  • Spontaneous and Engineered Deletions in the 3′ Noncoding Region of Tick-Borne Encephalitis Virus: Construction of Highly Attenuated Mutants of a Flavivirus

    Christian W. Mandl;Heidemarie Holzmann;Tamara Meixner;Susanne Rauscher

  • Fusion activity of flaviviruses: comparison of mature and immature (prM-containing) tick-borne encephalitis virions.

    Farshad Guirakhoo;Franz X. Heinz;Christian W. Mandl;Heidemarie Holzmann

  • Visualization of Central European Tick-Borne Encephalitis Infection in Fatal Human Cases

    Ellen Gelpi;Matthias Preusser;Ferenc Garzuly;Heidemarie Holzmann

  • Tick-borne encephalitis from eating goat cheese in a mountain region of Austria.

    Heidemarie Holzmann;Stephan W. Aberle;Karin Stiasny;Philipp Werner

  • Hepatitis B virus (HBV) and hepatitis C virus (HCV) infections in health care workers (HCWs): guidelines for prevention of transmission of HBV and HCV from HCW to patients.

    RN Gunson;D Shouval;M Roggendorf;H Zaaijer

  • Vaccination and Tick-borne Encephalitis, Central Europe

    Franz X. Heinz;Karin Stiasny;Heidemarie Holzmann;Marta Grgic-Vitek

  • Correlation between ELISA, hemagglutination inhibition, and neutralization tests after vaccination against tick‐borne encephalitis

    H. Holzmann;M. Kundi;K. Stiasny;J. Clement

  • Complete genomic sequence of Powassan virus: evaluation of genetic elements in tick-borne versus mosquito-borne flaviviruses.

    Christian W. Mandl;Heidemarie Holzmann;Christian Kunz;Franz X. Heinz

  • Infectious cDNA clones of tick-borne encephalitis virus European subtype prototypic strain Neudoerfl and high virulence strain Hypr.

    Christian W. Mandl;Michael Ecker;Heidemarie Holzmann;Christian Kunz

  • A single amino acid substitution in envelope protein E of tick-borne encephalitis virus leads to attenuation in the mouse model.

    H Holzmann;F X Heinz;C W Mandl;F Guirakhoo

  • Attenuation of tick-borne encephalitis virus by structure-based site-specific mutagenesis of a putative flavivirus receptor binding site.

    Christian W. Mandl;Steven L. Allison;Heidemarie Holzmann;Tamara Meixner

  • Inflammatory response in human tick-borne encephalitis: analysis of postmortem brain tissue

    Ellen Gelpi;Matthias Preusser;Ute Laggner;Ferenc Garzuly

  • In vitro-synthesized infectious RNA as an attenuated live vaccine in a flavivirus model

    Christian W. Mandl;Judith H. Aberle;Stephan W. Aberle;Heidemarie Holzmann

  • Increased Risk of Mother-to-Infant Transmission of Hepatitis C Virus by Intrapartum Infantile Exposure to Maternal Blood

    Christoph Steininger;Michael Kundi;Gerlinde Jatzko;Herbert Kiss

Frequent Co-Authors

Peter Ferenci
Peter Ferenci Medical University of Vienna
Stephan W. Aberle
Stephan W. Aberle Medical University of Vienna
Franz X. Heinz
Franz X. Heinz Medical University of Vienna
Karin Stiasny
Karin Stiasny Medical University of Vienna
Herwig Kollaritsch
Herwig Kollaritsch Medical University of Vienna
Ursula Wiedermann
Ursula Wiedermann Medical University of Vienna
Michael Trauner
Michael Trauner Medical University of Vienna
Franz Allerberger
Franz Allerberger University of Innsbruck
Christian W. Mandl
Christian W. Mandl Novartis (Switzerland)
Markus Peck-Radosavljevic
Markus Peck-Radosavljevic Klinikum Klagenfurt

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