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Gregg G. Gundersen

Gregg G. Gundersen

D-Index & Metrics

Biology and Biochemistry

D-Index
77
Citations
22572
World Ranking
4755
National Ranking
2301

Overview

Gregg G. Gundersen is affiliated with Columbia University in the United States and has conducted extensive research in the fields of biochemistry, genetics, and molecular biology. Their work focuses primarily on molecular biology and cell biology, with additional contributions in immunology, physiology, and cardiology and cardiovascular medicine.

The main topics addressed in Gundersen's research include nuclear structure and function, cellular mechanics and interactions, RNA research and splicing, cell death mechanisms and regulation, interferon and immune responses, RNA interference and gene delivery, as well as erythrocyte function and pathophysiology.

Gundersen's recent published papers include the following:

  • "Nuclear lamin isoforms differentially contribute to LINC complex-dependent nucleocytoskeletal coupling and whole-cell mechanics," 2022, Proceedings of the National Academy of Sciences
  • "Apoptotic stress induces Bax-dependent, caspase-independent redistribution of LINC complex nesprins," 2020, Cell Death Discovery
  • "Structures of FHOD1-Nesprin1/2 complexes reveal alternate binding modes for the FH3 domain of formins," 2021, Structure
  • "FHODs: Nuclear tethered formins for nuclear mechanotransduction," 2023, Frontiers in Cell and Developmental Biology
  • "LINC complex protein nesprin-2 has pro-apoptotic activity via Bcl-2 family proteins," 2024, Cell Death Discovery

The frequent co-authors collaborating with Gundersen include Susumu Antoku, Liora Lindenboim, Howard J. Worman, Reuven Stein, and Hila Zohar.

Gundersen regularly publishes in several academic journals, with the most frequent venues being:

  • Cell Death Discovery
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Proceedings of the National Academy of Sciences
  • Frontiers in Cell and Developmental Biology
  • Structure

Best Publications

  • Microtubule-induced focal adhesion disassembly is mediated by dynamin and focal adhesion kinase

    Ellen J Ezratty;Michael A Partridge;Gregg G Gundersen

  • EB1 and APC bind to mDia to stabilize microtubules downstream of Rho and promote cell migration.

    Ying Wen;Christina H Eng;Jan Schmoranzer;Noemi Cabrera-Poch;Noemi Cabrera-Poch

  • mDia mediates Rho-regulated formation and orientation of stable microtubules.

    Alexander F. Palazzo;Tiffani A. Cook;Arthur S. Alberts;Gregg G. Gundersen

  • Distinct populations of microtubules: Tyrosinated and nontyrosinated alpha tubulin are distributed differently in vivo

    Gregg G. Gundersen;Michael H. Kalnoski;Jeannette Chloë Bulinski

  • Nuclear Movement Regulated by Cdc42, MRCK, Myosin, and Actin Flow Establishes MTOC Polarization in Migrating Cells

    Edgar R. Gomes;Shantanu Jani;Gregg G. Gundersen

  • Microtubules and signal transduction.

    Gregg G Gundersen;Tiffani A Cook

  • Localized Stabilization of Microtubules by Integrin- and FAK-Facilitated Rho Signaling

    Alexander F. Palazzo;Christina H. Eng;David D. Schlaepfer;Eugene E. Marcantonio

  • Linear Arrays of Nuclear Envelope Proteins Harness Retrograde Actin Flow for Nuclear Movement

    G. W. Gant Luxton;Edgar R. Gomes;Edgar R. Gomes;Eric S. Folker;Erin Vintinner

  • Clathrin mediates integrin endocytosis for focal adhesion disassembly in migrating cells.

    Ellen J. Ezratty;Claire Bertaux;Eugene E. Marcantonio;Gregg G. Gundersen

  • Beyond polymer polarity: how the cytoskeleton builds a polarized cell

    Rong Li;Gregg G. Gundersen

  • Focal adhesion motility revealed in stationary fibroblasts

    Lubomir B. Smilenov;Alexei Mikhailov;Robert J. Pelham;Eugene E. Marcantonio

  • Cdc42, dynein, and dynactin regulate MTOC reorientation independent of Rho-regulated microtubule stabilization

    Alexander F. Palazzo;Hazel L. Joseph;Hazel L. Joseph;Ying-Jiun Chen;Denis L. Dujardin

  • Postpolymerization detyrosination of alpha-tubulin: a mechanism for subcellular differentiation of microtubules.

    G G Gundersen;S Khawaja;J C Bulinski

  • Kinesin Is a Candidate for Cross-bridging Microtubules and Intermediate Filaments SELECTIVE BINDING OF KINESIN TO DETYROSINATED TUBULIN AND VIMENTIN

    Guojuan Liao;Gregg G. Gundersen

  • Selective stabilization of microtubules oriented toward the direction of cell migration.

    Gregg G. Gundersen;Jeannette Chloe Bulinski

  • Stabilization and post‐translational modification of microtubules during cellular morphogenesis

    Jeannette C. Bulinski;Gregg G. Gundersen

  • Enhanced stability of microtubules enriched in detyrosinated tubulin is not a direct function of detyrosination level.

    S Khawaja;G G Gundersen;J C Bulinski

  • Nuclear ARP2/3 drives DNA break clustering for homology-directed repair.

    Benjamin R. Schrank;Tomas Aparicio;Yinyin Li;Wakam Chang

  • Rho Guanosine Triphosphatase Mediates the Selective Stabilization of Microtubules Induced by Lysophosphatidic Acid

    Tiffani A. Cook;Takayuki Nagasaki;Gregg G. Gundersen

  • Differential turnover of tyrosinated and detyrosinated microtubules

    Daniel R. Webster;Gregg G. Gundersen;Jeannette Chloe Bulinski;Gary G. Borisy

Frequent Co-Authors

Howard J. Worman
Howard J. Worman Columbia University
Richard B. Vallee
Richard B. Vallee Columbia University
Bruce L. Goode
Bruce L. Goode Brandeis University
I. Bernard Weinstein
I. Bernard Weinstein Columbia University
Bennett M. Shapiro
Bennett M. Shapiro VBL Therapeutics
Gary G. Borisy
Gary G. Borisy ADA Forsyth Institute
Guillaume Charras
Guillaume Charras London Centre for Nanotechnology
Oliver T. Fackler
Oliver T. Fackler University Hospital Heidelberg
Lynne Cassimeris
Lynne Cassimeris Lehigh University
Stephen P. Goff
Stephen P. Goff Columbia University Medical Center

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