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Genetics

D-Index
49
Citations
23180
World Ranking
3963
National Ranking
1710

Overview

Giorgio Sirugo is affiliated with the University of Pennsylvania in the United States. Their research primarily spans the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with a focus on Genetics, Infectious Diseases, Public Health, Environmental and Occupational Health, Epidemiology, and Molecular Biology.

The research areas studied by Giorgio Sirugo include:

  • Genomics and Rare Diseases
  • Genetic Associations and Epidemiology
  • SARS-CoV-2 and COVID-19 Research
  • Hemoglobinopathies and Related Disorders
  • COVID-19 Clinical Research Studies
  • Tuberculosis Research and Epidemiology
  • BRCA gene mutations in cancer

Some recent publications authored or co-authored by Giorgio Sirugo include:

  • Genome-wide analysis provides genetic evidence that ACE2 influences COVID-19 risk and yields risk scores associated with severe disease, 2022, Nature Genetics
  • The Penn Medicine BioBank: Towards a Genomics-Enabled Learning Healthcare System to Accelerate Precision Medicine in a Diverse Population, 2022, Journal of Personalized Medicine
  • Pan-ancestry exome-wide association analyses of COVID-19 outcomes in 586,157 individuals, 2021, The American Journal of Human Genetics
  • Malaria protection due to sickle haemoglobin depends on parasite genotype, 2021, Nature
  • Interaction between host genes and Mycobacterium tuberculosis lineage can affect tuberculosis severity: Evidence for coevolution?, 2020, PLoS Genetics

Giorgio Sirugo's frequent co-authors are:

  • Kirk A. Rockett
  • Dominic Kwiatkowski
  • Scott M. Williams
  • Daniel J. Rader
  • Anurag Verma

Common publication venues where Giorgio Sirugo has contributed multiple papers include:

  • Harvard Dataverse
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Zenodo (CERN European Organization for Nuclear Research)
  • OPAL (Open@LaTrobe) (La Trobe University)
  • Nature Genetics

Best Publications

  • Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls

    Paul R. Burton;David G. Clayton;Lon R. Cardon;Nick Craddock

  • Genome-wide association study identifies eight loci associated with blood pressure

    Christopher Newton-Cheh;Christopher Newton-Cheh;Toby Johnson;Toby Johnson;Vesela Gateva;Martin D. Tobin

  • Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants

    Paul R Burton;David G Clayton;Lon R Cardon;Nick Craddock

  • The Missing Diversity in Human Genetic Studies.

    Giorgio Sirugo;Scott M. Williams;Sarah A. Tishkoff

  • Induction of Apoptosis and Inhibition of Cell Proliferation bysurvivin Gene Targeting

    Grazia Ambrosini;Colette Adida;Giorgio Sirugo;Dario C. Altieri

  • Localization of type 1 diabetes susceptibility to the MHC class I genes HLA-B and HLA-A

    Sergey Nejentsev;Joanna M. M. Howson;Neil M. Walker;Jeffrey Szeszko

  • A Mal functional variant is associated with protection against invasive pneumococcal disease, bacteremia, malaria and tuberculosis.

    Chiea C Khor;Stephen J Chapman;Stephen J Chapman;Fredrik O Vannberg;Aisling Dunne

  • Genome-wide and fine-resolution association analysis of malaria in West Africa

    Muminatou Jallow;Yik Ying Teo;Yik Ying Teo;Kerrin S. Small;Kerrin S. Small;Kirk A. Rockett;Kirk A. Rockett

  • Genome-wide association analyses identifies a susceptibility locus for tuberculosis on chromosome 18q11.2.

    Thorsten Thye;Fredrik O. Vannberg;Sunny H. Wong;Ellis Owusu-Dabo

  • Reappraisal of known malaria resistance loci in a large multicenter study.

    Kirk A. Rockett;Geraldine M. Clarke;Kathryn Fitzpatrick

  • Common variants at 11p13 are associated with susceptibility to tuberculosis

    Thorsten Thye;Ellis Owusu-Dabo;Fredrik O Vannberg;Reinout van Crevel

  • DC-SIGN (CD209), pentraxin 3 and vitamin D receptor gene variants associate with pulmonary tuberculosis risk in West Africans.

    R Olesen;C Wejse;C Wejse;D R Velez;C Bisseye

  • Vitamin D Receptor Polymorphisms and Susceptibility to Tuberculosis in West Africa: A Case-Control and Family Study

    Liza Bornman;Sarah J Campbell;Katherine Fielding;Boubacar Bah

  • Variants in toll-like receptors 2 and 9 influence susceptibility to pulmonary tuberculosis in Caucasians, African-Americans, and West Africans

    Digna Rosa Velez;Christian Wejse;Christian Wejse;Martin E. Stryjewski;Eduardo Abbate

  • Evolution of haplotypes at the DRD2 locus.

    C. M. Castiglione;Amos S Deinard;W. C. Speed;G. Sirugo

  • Variants in the SP110 gene are associated with genetic susceptibility to tuberculosis in West Africa.

    Kerrie Tosh;Sarah J. Campbell;Katherine Fielding;Jackson Sillah

  • CD209 Genetic Polymorphism and Tuberculosis Disease

    Fredrik O. Vannberg;Stephen J Chapman;Chiea C. Khor;Kerrie Tosh

  • A global network for investigating the genomic epidemiology of malaria.

    Eric Akum Achidi;Tsiri Agbenyega;Stephen Allen;Olukemi Amodu

  • Friedreich's ataxia phenotype not linked to chromosome 9 and associated with selective autosomal recessive vitamin E deficiency in two inbred Tunisian families

    M. Ben Hamida;S. Belal;G. Sirugo;C. Ben Hamida

  • FTO gene variation and measures of body mass in an African population

    Branwen J Hennig;Anthony J Fulford;Giorgio Sirugo;Pura Rayco-Solon;Pura Rayco-Solon

Frequent Co-Authors

Dominic P. Kwiatkowski
Dominic P. Kwiatkowski University of Oxford
Scott M. Williams
Scott M. Williams Case Western Reserve University
Kirk A. Rockett
Kirk A. Rockett University of Oxford
David J. Conway
David J. Conway London School of Hygiene & Tropical Medicine
Adrian V. S. Hill
Adrian V. S. Hill University of Oxford
Melanie J. Newport
Melanie J. Newport Brighton and Sussex Medical School
Sarah A. Tishkoff
Sarah A. Tishkoff University of Pennsylvania
Andrew M. Prentice
Andrew M. Prentice London School of Hygiene & Tropical Medicine
Kenneth K. Kidd
Kenneth K. Kidd Yale University
Yik Ying Teo
Yik Ying Teo National University of Singapore

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