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Fumihiko Takeuchi

Fumihiko Takeuchi

D-Index & Metrics

Genetics

D-Index
67
Citations
29870
World Ranking
2490
National Ranking
97

Overview

Fumihiko Takeuchi is affiliated with Juntendo University in Japan and has made significant contributions to the fields of biochemistry, genetics, molecular biology, and medicine. Their research encompasses a broad range of subfields, including genetics, molecular biology, cardiology and cardiovascular medicine, endocrinology, diabetes and metabolism, and epidemiology.

Their recent publications reflect a strong focus on genetic associations and epidemiology, along with specific investigations into cancer-related molecular mechanisms research, liver disease diagnosis and treatment, hormonal regulation and hypertension, epigenetics and DNA methylation, renin-angiotensin system studies, and RNA modifications related to cancer.

Frequent publication venues for Takeuchi include UNC Libraries, bioRxiv (Cold Spring Harbor Laboratory), Heart Lung and Circulation, Nature, and Communications Biology. This range demonstrates a sustained commitment to disseminating research across a variety of platforms connected to genetics and medical sciences.

Recent papers include the following:

  • "Multi-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation," 2022, Nature Genetics
  • "Identification of type 2 diabetes loci in 433,540 East Asian individuals," 2020, Nature
  • "Genetic drivers of heterogeneity in type 2 diabetes pathophysiology," 2024, Nature
  • "A polygenic risk score improves risk stratification of coronary artery disease: a large-scale prospective Chinese cohort study," 2022, European Heart Journal
  • "Identification of genetic effects underlying type 2 diabetes in South Asian and European populations," 2022, Communications Biology

Takeuchi often collaborates with several researchers in the field, including Norihiro Kato, Masato Isono, Lauren E. Petty, Jirong Long, and Cassandra N. Spracklen. The frequency of these partnerships indicates a network focused on genetics and epidemiological studies.

Main topics addressed in Takeuchi's work cover:

  • Genetic Associations and Epidemiology
  • Cancer-related molecular mechanisms research
  • Liver Disease Diagnosis and Treatment
  • Hormonal Regulation and Hypertension
  • Epigenetics and DNA Methylation
  • Renin-Angiotensin System Studies
  • RNA modifications and cancer

The body of research highlights a multidisciplinary approach across genetics, molecular biology, and cardiovascular and metabolic medicine. This comprehensive research portfolio underscores Takeuchi's involvement in advancing understanding of complex diseases, particularly type 2 diabetes and coronary artery disease, from a genetic and epidemiological perspective.

Best Publications

  • Integrating common and rare genetic variation in diverse human populations

    D M Altshuler;R A Gibbs;L Peltonen

  • Genome and virulence determinants of high virulence community-acquired MRSA.

    Tadashi Baba;Fumihiko Takeuchi;Makoto Kuroda;Harumi Yuzawa

  • Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries

    Mary F. Feitosa;Aldi T. Kraja;Daniel I. Chasman;Yun J. Sung

  • Novel Type V Staphylococcal Cassette Chromosome mec Driven by a Novel Cassette Chromosome Recombinase, ccrC

    Teruyo Ito;Xiao Xue Ma;Fumihiko Takeuchi;Keiko Okuma

  • Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility.

    Anubha Mahajan;Min Jin Go;Weihua Zhang;Jennifer E. Below

  • The trans-ancestral genomic architecture of glycemic traits

    Ji Chen;Ji Chen;Cassandra N. Spracklen;Cassandra N. Spracklen;Gaëlle Marenne;Gaëlle Marenne;Arushi Varshney

  • Newly identified genetic risk variants for celiac disease related to the immune response

    Karen A Hunt;Alexandra Zhernakova;Graham Turner;Graham A R Heap

  • A genome-wide association study confirms VKORC1, CYP2C9, and CYP4F2 as principal genetic determinants of warfarin dose

    Fumihiko Takeuchi;Ralph McGinnis;Stephane Bourgeois;Chris P. Barnes

  • Meta-analysis of genome-wide association studies identifies eight new loci for type 2 diabetes in east Asians

    Yoon Shin Cho;Chien Hsiun Chen;Chien Hsiun Chen;Cheng Hu;Jirong Long

  • Genome Sequence of Staphylococcus aureus Strain Newman and Comparative Analysis of Staphylococcal Genomes: Polymorphism and Evolution of Two Major Pathogenicity Islands

    Tadashi Baba;Taeok Bae;Olaf Schneewind;Fumihiko Takeuchi

  • Two-component system VraSR positively modulates the regulation of cell-wall biosynthesis pathway in Staphylococcus aureus.

    Makoto Kuroda;Hiroko Kuroda;Taku Oshima;Fumihiko Takeuchi

  • Meta-analysis of genome-wide association studies identifies common variants associated with blood pressure variation in east Asians

    Norihiro Kato;Fumihiko Takeuchi;Yasuharu Tabara;Tanika N. Kelly

  • Genome-wide association study in individuals of South Asian ancestry identifies six new type 2 diabetes susceptibility loci

    Jaspal S Kooner;Danish Saleheen;Xueling Sim;Joban Sehmi;Joban Sehmi

  • Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function

    Cristian Pattaro;Alexander Teumer;Mathias Gorski;Audrey Y. Chu

  • Meta-analysis identifies common variants associated with body mass index in east Asians

    Wanqing Wen;Yoon Shin Cho;Wei Zheng;Rajkumar Dorajoo;Rajkumar Dorajoo

  • Impact of common genetic determinants of Hemoglobin A1c on type 2 diabetes risk and diagnosis in ancestrally diverse populations: A transethnic genome-wide meta-analysis

    Eleanor Wheeler;Aaron Leong;Ching-Ti Liu;Marie-France Hivert

  • Whole-Genome Sequencing of Staphylococcus haemolyticus Uncovers the Extreme Plasticity of Its Genome and the Evolution of Human-Colonizing Staphylococcal Species

    Fumihiko Takeuchi;Shinya Watanabe;Tadashi Baba;Harumi Yuzawa

  • Identification of type 2 diabetes loci in 433,540 East Asian individuals

    Cassandra N Spracklen;Cassandra N Spracklen;Momoko Horikoshi;Young Jin Kim;Kuang Lin

  • Trans-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation

    Mahajan A;Spracklen Cn;Zhang W;Ng Mc

  • Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility

    Anubha Mahajan;Min Jin Go;Weihua Zhang;Jennifer E. Below

Frequent Co-Authors

Norihiro Kato
Norihiro Kato National Center For Global Health and Medicine
Tien Yin Wong
Tien Yin Wong Tsinghua University
Jianjun Liu
Jianjun Liu Genome Institute of Singapore
Tomohiro Katsuya
Tomohiro Katsuya Osaka University
John C. Chambers
John C. Chambers Guy's and St Thomas' NHS Foundation Trust
Yik Ying Teo
Yik Ying Teo National University of Singapore
Chiea Chuen Khor
Chiea Chuen Khor Agency for Science, Technology and Research
Xueling Sim
Xueling Sim National University of Singapore
Weihua Zhang
Weihua Zhang Imperial College London
Jaspal S. Kooner
Jaspal S. Kooner Imperial College London

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